MSDS Name:T4 Polynucleotide Kinase
Synonym:None Known

EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation.
Chronic:
No information found.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide. For large fires, use water spray, fog or alcohol-resistant foam.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Handling:
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store at -20C.

Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 0-01-1: CAS# 56-81-5: United Kingdom, WEL - TWA: 10 mg/m3 TWA (mist) United Kingdom, WEL - STEL: 30 mg/m3 STEL (mist) United States OSHA: 15 mg/m3 TWA (total dust); 5 mg/m3 TWA (respirable fraction) Belgium - TWA: 10 mg/m3 VLE (mist) France - VME: 10 mg/m3 VME Malaysia: 10 mg/m3 TWA (mist) Netherlands: 10 mg/m3 MAC (mist) Spain: 10 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Physical State: Liquid
Color: colorless
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: 400 deg C ( 752.00 deg F)
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0

Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Excess heat, exposure to flame, pressure.
Incompatibilities with Other Materials:
Oxidizing agents, acids, alkalis.
Hazardous Decomposition Products:
None.
Hazardous Polymerization: Has not been reported.

RTECS#:
CAS# 0-01-1 unlisted.
CAS# 56-81-5: MA8050000 LD50/LC50:
Not available.
CAS# 56-81-5: Draize test, rabbit, eye: 126 mg Mild; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >570 mg/m3/1H; Oral, mouse: LD50 = 4090 mg/kg; Oral, rabbit: LD50 = 27 gm/kg; Oral, rat: LD50 = 12600 mg/kg; Skin, rabbit: LD50 = >10 gm/kg.
Carcinogenicity:
No hazardous ingredients per 29 CFR 1910.1200 - Not listed by ACGIH, IARC, or NTP.
Glycerol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

IATA
Shipping Name: CARBON DIOXIDE, SOLID
Hazard Class: 9
UN Number: 1845
Packing Group: III
IMO
Shipping Name: CARBON DIOXIDE, SOLID
Hazard Class: 9
UN Number: 1845
Packing Group: III
RID/ADR
Shipping Name: CARBON DIOXIDE, SOLID
Hazard Class: 9
UN Number: 1845
Packing group: III

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 0-01-1: No information available.
CAS# 56-81-5: 0
Canada
CAS# 56-81-5 is listed on Canadas DSL List.
CAS# 0-01-1 is not listed on Canadas Ingredient Disclosure List.
CAS# 56-81-5 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 0-01-1 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 56-81-5 is listed on the TSCA inventory.