Name:
Tebbe reagent 0.5M solution in toluene
Synonym:
Bis(cyclopentadienyl-??-chloro(dimethylaluminum-??-methylenetitaniu
CAS:
108-88-3
Section 1 - Chemical Product
MSDS Name:Tebbe reagent 0.5M solution in toluene
Synonym:Bis(cyclopentadienyl-??-chloro(dimethylaluminum-??-methylenetitaniu
Synonym:Bis(cyclopentadienyl-??-chloro(dimethylaluminum-??-methylenetitaniu
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 108-88-3 | Toluene | 71.4 | 203-625-9 |
| Hazard Symbols: T F Risk Phrases: 11 23/24/25 34 63 67 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Toxic by inhalation, in contact with skin and if swallowed. Causes burns. Possible risk of harm to the unborn child.
Vapours may cause drowsiness and dizziness.Moisture sensitive.Air sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. Toxic in contact with skin.
Ingestion:
May cause irritation of the digestive tract. Causes gastrointestinal tract burns. Toxic if swallowed.
Inhalation:
Causes chemical burns to the respiratory tract. Toxic if inhaled.
May cause chest pain and lung irritation.
Chronic:
Prolonged or repeated exposure affects the nervous system.
Highly flammable. Toxic by inhalation, in contact with skin and if swallowed. Causes burns. Possible risk of harm to the unborn child.
Vapours may cause drowsiness and dizziness.Moisture sensitive.Air sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. Toxic in contact with skin.
Ingestion:
May cause irritation of the digestive tract. Causes gastrointestinal tract burns. Toxic if swallowed.
Inhalation:
Causes chemical burns to the respiratory tract. Toxic if inhaled.
May cause chest pain and lung irritation.
Chronic:
Prolonged or repeated exposure affects the nervous system.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Containers may explode in the heat of a fire.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Containers may explode in the heat of a fire.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool.
Section 7 - HANDLING and STORAGE
Handling:
Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep under a nitrogen blanket.
Flammables-area.
Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep under a nitrogen blanket.
Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 108-88-3: United Kingdom, WEL - TWA: 50 ppm TWA; 191 mg/m3 TWA United Kingdom, WEL - STEL: 150 ppm STEL; 574 mg/m3 STEL United States OSHA: 200 ppm TWA; 300 ppm Ceiling Belgium - TWA: 50 ppm VLE; 191 mg/m3 VLE France - VME: 100 ppm VME; 375 mg/m3 VME France - VLE: 150 ppm VLE; 550 mg/m3 VLE Germany: 50 ppm TWA; 190 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 188 mg/m3 OEL Malaysia: 50 ppm TWA; 188 mg/m3 TWA Netherlands: 40 ppm MAC; 150 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 191 mg/m3 VLA-ED CAS# 67719-69-1: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 108-88-3: United Kingdom, WEL - TWA: 50 ppm TWA; 191 mg/m3 TWA United Kingdom, WEL - STEL: 150 ppm STEL; 574 mg/m3 STEL United States OSHA: 200 ppm TWA; 300 ppm Ceiling Belgium - TWA: 50 ppm VLE; 191 mg/m3 VLE France - VME: 100 ppm VME; 375 mg/m3 VME France - VLE: 150 ppm VLE; 550 mg/m3 VLE Germany: 50 ppm TWA; 190 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 188 mg/m3 OEL Malaysia: 50 ppm TWA; 188 mg/m3 TWA Netherlands: 40 ppm MAC; 150 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 191 mg/m3 VLA-ED CAS# 67719-69-1: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: dark red
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 4 deg C ( 39.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 0.927
Molecular Formula: C13H18AlCllTi
Molecular Weight: 284.62
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, aluminum oxide, oxides of titanium.
Hazardous Polymerization: Has not been reported
Not available.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, aluminum oxide, oxides of titanium.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 108-88-3: XS5250000 CAS# 67719-69-1 unlisted.
LD50/LC50:
CAS# 108-88-3: Draize test, rabbit, eye: 870 ug Mild; Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 435 mg Mild; Draize test, rabbit, skin: 500 mg Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 400 ppm/24H; Inhalation, mouse: LC50 = 30000 mg/m3/2H; Inhalation, mouse: LC50 = 19900 mg/m3/7H; Inhalation, mouse: LC50 = 10000 mg/m3; Inhalation, rat: LC50 = 49 gm/m3/4H; Oral, rat: LD50 = 636 mg/kg; Skin, rabbit: LD50 = 14100 uL/kg.
CAS# 67719-69-1.
Carcinogenicity:
Toluene - Not listed by ACGIH, IARC, or NTP.
Tebbe reagent - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 108-88-3: XS5250000 CAS# 67719-69-1 unlisted.
LD50/LC50:
CAS# 108-88-3: Draize test, rabbit, eye: 870 ug Mild; Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 435 mg Mild; Draize test, rabbit, skin: 500 mg Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 400 ppm/24H; Inhalation, mouse: LC50 = 30000 mg/m3/2H; Inhalation, mouse: LC50 = 19900 mg/m3/7H; Inhalation, mouse: LC50 = 10000 mg/m3; Inhalation, rat: LC50 = 49 gm/m3/4H; Oral, rat: LD50 = 636 mg/kg; Skin, rabbit: LD50 = 14100 uL/kg.
CAS# 67719-69-1.
Carcinogenicity:
Toluene - Not listed by ACGIH, IARC, or NTP.
Tebbe reagent - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.*
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
IMO
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
RID/ADR
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3 (8)
UN Number: 2924
Packing group: II
USA RQ: CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T F
Risk Phrases:
R 11 Highly flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 34 Causes burns.
R 63 Possible risk of harm to the unborn child.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 25 Avoid contact with eyes.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
CAS# 67719-69-1: No information available.
Canada
CAS# 108-88-3 is listed on Canadas DSL List.
CAS# 108-88-3 is listed on Canadas Ingredient Disclosure List.
CAS# 67719-69-1 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 108-88-3 is listed on the TSCA inventory.
CAS# 67719-69-1 is not listed on the TSCA inventory.
It is for research and development use only.
