Name:
tert-Butylmagnesium chloride 2.0M solution in diethyl ether
Synonym:
None Known
CAS:
60-29-7
Section 1 - Chemical Product
MSDS Name:tert-Butylmagnesium chloride 2.0M solution in diethyl ether
Synonym:None Known
Synonym:None Known
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 60-29-7 | Ethyl ether | 72 | 200-467-2 |
| Hazard Symbols: F+ C Risk Phrases: 12 14/15 19 22 34 66 67 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Extremely flammable. Reacts violently with water liberating extremely flammable gases. May form explosive peroxides. Harmful if swallowed. Causes burns. Repeated exposure may cause skin dryness or cracking. Vapours may cause drowsiness and dizziness.Water-reactive.Light sensitive.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. Causes redness and pain.
Skin:
Causes skin burns. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
Harmful if swallowed. Aspiration hazard. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma.
Causes gastrointestinal tract burns. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Causes chemical burns to the respiratory tract. Exposure to high concentrations may produce narcosis, nausea and loss of consciousness. Inhalation of vapors may cause drowsiness and dizziness.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure to high vapor concentrations may cause eye injury. Repeated exposures may be habit forming.
Extremely flammable. Reacts violently with water liberating extremely flammable gases. May form explosive peroxides. Harmful if swallowed. Causes burns. Repeated exposure may cause skin dryness or cracking. Vapours may cause drowsiness and dizziness.Water-reactive.Light sensitive.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. Causes redness and pain.
Skin:
Causes skin burns. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
Harmful if swallowed. Aspiration hazard. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma.
Causes gastrointestinal tract burns. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Causes chemical burns to the respiratory tract. Exposure to high concentrations may produce narcosis, nausea and loss of consciousness. Inhalation of vapors may cause drowsiness and dizziness.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure to high vapor concentrations may cause eye injury. Repeated exposures may be habit forming.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively. Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance.
Skin:
In case of contact, immediately flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively. Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Will burn if involved in a fire. Extremely flammable. Material will readily ignite at room temperature. Water Reactive. Material will react with water and may release a flammable and/or toxic gas.
Containers may explode in the heat of a fire. May form explosive peroxides. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire.
Extinguishing Media:
Use approved class D extinguishing agents or smother with dry sand, clay, or sodium bicarbonate. DO NOT USE WATER OR FOAM.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Will burn if involved in a fire. Extremely flammable. Material will readily ignite at room temperature. Water Reactive. Material will react with water and may release a flammable and/or toxic gas.
Containers may explode in the heat of a fire. May form explosive peroxides. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire.
Extinguishing Media:
Use approved class D extinguishing agents or smother with dry sand, clay, or sodium bicarbonate. DO NOT USE WATER OR FOAM.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Do not expose spill to water. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Do not expose spill to water. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas.
Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Do not allow contact with water. Use only in a chemical fume hood. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Avoid breathing vapor.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Flammables-area. Corrosives area. Water free area. Store under nitrogen. Keep away from oxidizing agents. Containers should be dated when opened and tested periodically for the presence of peroxides.
Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas.
Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Do not allow contact with water. Use only in a chemical fume hood. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Avoid breathing vapor.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Flammables-area. Corrosives area. Water free area. Store under nitrogen. Keep away from oxidizing agents. Containers should be dated when opened and tested periodically for the presence of peroxides.
Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 60-29-7: United Kingdom, WEL - TWA: 100 ppm TWA; 310 mg/m3 TWA United Kingdom, WEL - STEL: 200 ppm STEL; 620 mg/m3 STEL United States OSHA: 400 ppm TWA; 1200 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 308 mg/m3 VLE Belgium - STEL: 200 ppm VLE; 616 mg/m3 VLE France - VME: 400 ppm VME; 1200 mg/m3 VME France - VLE: 500 ppm VLE; 1500 mg/m3 VLE Germany: 400 ppm TWA; 1200 mg/m3 TWA Japan: 400 ppm OEL; 1200 mg/m3 OEL Malaysia: 400 ppm TWA; 1210 mg/m3 TWA Netherlands: 200 ppm STEL; 616 mg/m3 STEL Netherlands: 100 ppm MAC; 308 mg/m3 MAC Russia: 300 mg/m3 TWA Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 616 mg/m3 VLA-EC CAS# 677-22-5: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 60-29-7: United Kingdom, WEL - TWA: 100 ppm TWA; 310 mg/m3 TWA United Kingdom, WEL - STEL: 200 ppm STEL; 620 mg/m3 STEL United States OSHA: 400 ppm TWA; 1200 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 308 mg/m3 VLE Belgium - STEL: 200 ppm VLE; 616 mg/m3 VLE France - VME: 400 ppm VME; 1200 mg/m3 VME France - VLE: 500 ppm VLE; 1500 mg/m3 VLE Germany: 400 ppm TWA; 1200 mg/m3 TWA Japan: 400 ppm OEL; 1200 mg/m3 OEL Malaysia: 400 ppm TWA; 1210 mg/m3 TWA Netherlands: 200 ppm STEL; 616 mg/m3 STEL Netherlands: 100 ppm MAC; 308 mg/m3 MAC Russia: 300 mg/m3 TWA Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 616 mg/m3 VLA-EC CAS# 677-22-5: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: gray to brown black
Odor: pungent odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: vigorous reaction
Specific Gravity/Density: 0.800
Molecular Formula: C4H9ClMg
Molecular Weight: 116.87
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Reacts violently with water. Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess heat, exposure to moist air or water, direct sunlight..
Incompatibilities with Other Materials:
Water, oxidizing agents, bases, acids, acidic conditions, alcohols, nitric acid.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, peroxides, chloride fumes, oxides of magnesium.
Hazardous Polymerization: Has not been reported
Reacts violently with water. Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess heat, exposure to moist air or water, direct sunlight..
Incompatibilities with Other Materials:
Water, oxidizing agents, bases, acids, acidic conditions, alcohols, nitric acid.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide, peroxides, chloride fumes, oxides of magnesium.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 60-29-7: KI5775000 CAS# 677-22-5 unlisted.
LD50/LC50:
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, mouse: LD50 = 1760 mg/kg; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 677-22-5.
Carcinogenicity:
Ethyl ether - Not listed by ACGIH, IARC, or NTP.
tert-Butylmagnesium chloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 60-29-7: KI5775000 CAS# 677-22-5 unlisted.
LD50/LC50:
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, mouse: LD50 = 1760 mg/kg; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 677-22-5.
Carcinogenicity:
Ethyl ether - Not listed by ACGIH, IARC, or NTP.
tert-Butylmagnesium chloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox testIf ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox testIf ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ORGANOMETALLIC COMPOUND DISPERSION, WATER-REACTIVE
, FLAMMABLE, N.O.S.*
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: I
IMO
Shipping Name: ORGANOMETALLIC COMPOUND DISPERSION, WATER-REACTIVE
, FLAMMABLE, N.O.S.
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: I
RID/ADR
Shipping Name: ORGANOMETALLIC COMPOUND DISPERSION, WATER-REACTIVE
, FLAMMABLE, N.O.S.
Hazard Class: 4.3 (3)
UN Number: 3207
Packing group: I
USA RQ: CAS# 60-29-7: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F+ C
Risk Phrases:
R 12 Extremely flammable.
R 14/15 Reacts violently with water liberating
extremely flammable gases.
R 19 May form explosive peroxides.
R 22 Harmful if swallowed.
R 34 Causes burns.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 6A Keep under nitrogen.
S 8 Keep container dry.
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 43B In case of fire, use fire-fighting equipment
on basis of sodium chloride, sodium bicarbonate (never
use water).
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 60-29-7: 1
CAS# 677-22-5: No information available.
Canada
CAS# 60-29-7 is listed on Canadas DSL List.
CAS# 60-29-7 is listed on Canadas Ingredient Disclosure List.
CAS# 677-22-5 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 60-29-7 is listed on the TSCA inventory.
CAS# 677-22-5 is not listed on the TSCA inventory.
It is for research and development use only.
