Name:
Tolylene-2 4-Diisocyanate Tech. 80%
Synonym:
4-Methyl-1,3-phenylene diisocyanate; TDI; Toluene-2,4-diisocyanate
CAS:
584-84-9
Section 1 - Chemical Product
MSDS Name:Tolylene-2 4-Diisocyanate Tech. 80%
Synonym:4-Methyl-1,3-phenylene diisocyanate; TDI; Toluene-2,4-diisocyanate
Synonym:4-Methyl-1,3-phenylene diisocyanate; TDI; Toluene-2,4-diisocyanate
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 584-84-9 | Tolylene-2,4-diisocyanate | 80 | 209-544-5 |
| Hazard Symbols: T+ Risk Phrases: 26 36/37/38 40 42/43 52/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Very toxic by inhalation. Irritating to eyes, respiratory system and skin. Possible risks of irreversible effects. May cause sensitization by inhalation and skin contact. Harmful to aquatic organisms; may cause long-term adverse effects in the aquatic environment.Cancer suspect agent.Lachrymator (substance which increases the flow of tears).Light sensitive.Water-Reactive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Causes gastrointestinal tract irritation.
Inhalation:
May be fatal if inhaled. Causes respiratory tract irritation.
Chronic:
Chronic overexposure to isocyanates has been reported to cause lung damage, including decreased lung fuction, which may be permanent.
Very toxic by inhalation. Irritating to eyes, respiratory system and skin. Possible risks of irreversible effects. May cause sensitization by inhalation and skin contact. Harmful to aquatic organisms; may cause long-term adverse effects in the aquatic environment.Cancer suspect agent.Lachrymator (substance which increases the flow of tears).Light sensitive.Water-Reactive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Causes gastrointestinal tract irritation.
Inhalation:
May be fatal if inhaled. Causes respiratory tract irritation.
Chronic:
Chronic overexposure to isocyanates has been reported to cause lung damage, including decreased lung fuction, which may be permanent.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Get medical aid if symptoms occur.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation.
Antidote: Always have a cyanide antidote kit on hand when working with cyanide compounds. Get medical advice to use.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Get medical aid if symptoms occur.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation.
Antidote: Always have a cyanide antidote kit on hand when working with cyanide compounds. Get medical advice to use.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For large fires, use water spray or fog. Do NOT get water inside containers. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. For small fires, use dry chemical or carbon dioxide.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For large fires, use water spray or fog. Do NOT get water inside containers. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. For small fires, use dry chemical or carbon dioxide.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Do not expose spill to water. Do not get water inside containers. Approach spill from upwind.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Do not expose spill to water. Do not get water inside containers. Approach spill from upwind.
Section 7 - HANDLING and STORAGE
Handling:
Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Avoid breathing dust, vapor, mist, or gas. Do not allow contact with water.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store under an inert atmosphere.
Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Avoid breathing dust, vapor, mist, or gas. Do not allow contact with water.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store under an inert atmosphere.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear chemical goggles.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear chemical goggles.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: clear to yellow
Odor: pungent odor - sharp odor
pH: Not available.
Vapor Pressure: 1 mm Hg @ 80 deg C
Viscosity: Not available.
Boiling Point: 484 deg F
Freezing/Melting Point: 19.5-21.5 deg C
Autoignition Temperature: Not available.
Flash Point: 121 deg C ( 249.80 deg F)
Explosion Limits, lower: 0.9 vol%
Explosion Limits, upper: 9.5 vol%
Decomposition Temperature:
Solubility in water: Reacts.
Specific Gravity/Density: 1.2200g/cm3
Molecular Formula: C9H6N2O2
Molecular Weight: 174.16
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Hazardous polymerization and/or hazardous decomposition may occur on contact with water or on exposure to heat.
Conditions to Avoid:
Light, contact with water, heat.
Incompatibilities with Other Materials:
Water, oxidizing agents, bases, alcohols, amines, organic acids, organometallic compounds.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.
Stable under normal temperatures and pressures. Hazardous polymerization and/or hazardous decomposition may occur on contact with water or on exposure to heat.
Conditions to Avoid:
Light, contact with water, heat.
Incompatibilities with Other Materials:
Water, oxidizing agents, bases, alcohols, amines, organic acids, organometallic compounds.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 584-84-9: CZ6300000 LD50/LC50:
CAS# 584-84-9: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg/24H Moderate; Inhalation, mouse: LC50 = 10 ppm/4H; Inhalation, rabbit: LC50 = 11 ppm/4H; Inhalation, rat: LC50 = 14 ppm/4H; Oral, rat: LD50 = 5800 mg/kg; Skin, rabbit: LD50 = >16 mL/kg.
Carcinogenicity:
Tolylene-2,4-diisocyanate - ACGIH: A4 - Not Classifiable as a Human Carcinogen NIOSH: occupational carcinogen See actual entry in RTECS for complete information.
CAS# 584-84-9: CZ6300000 LD50/LC50:
CAS# 584-84-9: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg/24H Moderate; Inhalation, mouse: LC50 = 10 ppm/4H; Inhalation, rabbit: LC50 = 11 ppm/4H; Inhalation, rat: LC50 = 14 ppm/4H; Oral, rat: LD50 = 5800 mg/kg; Skin, rabbit: LD50 = >16 mL/kg.
Carcinogenicity:
Tolylene-2,4-diisocyanate - ACGIH: A4 - Not Classifiable as a Human Carcinogen NIOSH: occupational carcinogen See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing Group: II
IMO
Shipping Name: TOLUENE DIISOCYANATE
Hazard Class: 6.1
UN Number: 2078
Packing Group: II
RID/ADR
Shipping Name: TOLUENE DIISOCYANATE
Dangerous Goods Code: 6.1(19B)
UN Number: 2078
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26 Very toxic by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 40 Possible risks of irreversible effects.
R 42/43 May cause sensitization by inhalation and
skin contact.
R 52/53 Harmful to aquatic organisms; may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 584-84-9: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 584-84-9 is listed on Canadas DSL List.
CAS# 584-84-9 is listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 584-84-9: OEL-ARAB Republic of Egypt:TWA 0.02 ppm (0.14 mg/m3)
OEL-BELGIUM:TWA 0.005 ppm (0.036 mg/m3);STEL 0.02 ppm
OEL-CZECHOSLOVAKIA:TWA 0.07 mg/m3;STEL 0.14 mg/m3
OEL-DENMARK:TWA 0.005 ppm (0.035 mg/m3);Carcinoge
OEL-FRANCE:TWA 0.01 ppm (0.08 mg/m3);STEL 0.02 pp (0.16 mg/m3)
OEL-GERMANY:TWA 0.01 ppm (0.07 mg/m3)
OEL-HUNGARY:STEL 0.04 mg/m3
OEL-JAPAN:TWA 0.02 ppm (0.14 mg/m3)
OEL-THE NETHERLANDS:TWA 0.02 ppm (0.14 mg/m3);Ski
OEL-THE PHILIPPINES:TWA 0.02 ppm (0.14 mg/m3)
OEL-RUSSIA:STEL 0.05 mg/m3
OEL-SWEDEN:TWA 0.005 ppm (0.04 mg/m3);STEL 0.01 ppm (0.07 mg/m3)
OEL-SWITZERLAND:TWA 0.005 ppm (0.04 mg/m3);STEL 0.01 ppm
OEL-THAILAND:TWA 0.02 ppm (0.14 mg/m3)
OEL-TURKEY:TWA 0.02 ppm (0.14 mg/m3)
OEL-UNITED KINGDOM:TWA 0.02 mg/m3;STEL 0.07 mg/m3
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 584-84-9 is listed on the TSCA inventory.
