Name:
Tris Borate EDTA 10X Powder
Synonym:
Tris-Boric Acid-ETDA Powder; TBE Powde
CAS:
60-00-4
Section 1 - Chemical Product
MSDS Name:Tris Borate EDTA 10X Powder
Synonym:Tris-Boric Acid-ETDA Powder; TBE Powde
Synonym:Tris-Boric Acid-ETDA Powder; TBE Powde
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 60-00-4 | Ethylenediaminetetraacetic acid | 3.5 | 200-449-4 |
| Hazard Symbols: T Risk Phrases: 36/37/38 60 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. May impair fertility.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin irritation. May be absorbed through damaged or abraded skin in harmful amounts.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause gastric disturbances and electrolytic imbalance. May cause central nervous system effects. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Inhalation:
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic poisoning by boron compounds, borism, may be little more than dry skin and mucous membranes, followed by appearance of a red tongue, patchy alopecia (hair loss), cracked lips, and conjunctivitis.
Infants and young children are more susceptible to boric acid poisoning than adults. May cause adverse reproductive effects.
Irritating to eyes, respiratory system and skin. May impair fertility.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin irritation. May be absorbed through damaged or abraded skin in harmful amounts.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause gastric disturbances and electrolytic imbalance. May cause central nervous system effects. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Inhalation:
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic poisoning by boron compounds, borism, may be little more than dry skin and mucous membranes, followed by appearance of a red tongue, patchy alopecia (hair loss), cracked lips, and conjunctivitis.
Infants and young children are more susceptible to boric acid poisoning than adults. May cause adverse reproductive effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Antidote: None reported.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Antidote: None reported.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 60-00-4: CAS# 77-86-1: CAS# 10043-35-3: Russia: 10 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 60-00-4: CAS# 77-86-1: CAS# 10043-35-3: Russia: 10 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: Mixture
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Decarboxylates above 150C.
Conditions to Avoid:
High temperatures, incompatible materials, dust generation.
Incompatibilities with Other Materials:
Reaction with strong reducing agents, such as metal hydrides or alkali metals, will generate hydrogen gas, which could create an explosion hazard., caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), acetic anhydride, alkali carbonates.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, nitrogen oxides (NOx) and ammonia (NH3), oxides of boron.
Hazardous Polymerization: Has not been reported.
Stable at room temperature in closed containers under normal storage and handling conditions. Decarboxylates above 150C.
Conditions to Avoid:
High temperatures, incompatible materials, dust generation.
Incompatibilities with Other Materials:
Reaction with strong reducing agents, such as metal hydrides or alkali metals, will generate hydrogen gas, which could create an explosion hazard., caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), acetic anhydride, alkali carbonates.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, nitrogen oxides (NOx) and ammonia (NH3), oxides of boron.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 60-00-4: AH4025000 CAS# 77-86-1: TY2900000 CAS# 10043-35-3: ED4550000 ED4560000 LD50/LC50:
CAS# 60-00-4: Oral, mouse: LD50 = 30 mg/kg.
CAS# 77-86-1: Oral, rat: LD50 = 5900 mg/kg.
CAS# 10043-35-3: Oral, mouse: LD50 = 3450 mg/kg; Oral, rat: LD50 = 2660 mg/kg; Oral, rat: LD50 = 2500 mg/kg.
Carcinogenicity:
Ethylenediaminetetraacetic acid - Not listed by ACGIH, IARC, or NTP.
Tris (hydroxymethyl) aminomethane - Not listed by ACGIH, IARC, or NTP.
Boric acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 60-00-4: AH4025000 CAS# 77-86-1: TY2900000 CAS# 10043-35-3: ED4550000 ED4560000 LD50/LC50:
CAS# 60-00-4: Oral, mouse: LD50 = 30 mg/kg.
CAS# 77-86-1: Oral, rat: LD50 = 5900 mg/kg.
CAS# 10043-35-3: Oral, mouse: LD50 = 3450 mg/kg; Oral, rat: LD50 = 2660 mg/kg; Oral, rat: LD50 = 2500 mg/kg.
Carcinogenicity:
Ethylenediaminetetraacetic acid - Not listed by ACGIH, IARC, or NTP.
Tris (hydroxymethyl) aminomethane - Not listed by ACGIH, IARC, or NTP.
Boric acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Water flea Daphnia: LC50 = 115.0-153.0 mg/L; 48 Hr.; Static ConditionFish: Rainbow trout: LC50=150mg B/L; 24-dayFish: Goldfish: LC50=46mg B/L; 7-dayMosquito fish (fresh water) TLm=1800 ppm/24H Mosquito fish (fresh water) TLm=1800 ppm/24H
Water flea Daphnia: LC50 = 115.0-153.0 mg/L; 48 Hr.; Static ConditionFish: Rainbow trout: LC50=150mg B/L; 24-dayFish: Goldfish: LC50=46mg B/L; 7-dayMosquito fish (fresh water) TLm=1800 ppm/24H Mosquito fish (fresh water) TLm=1800 ppm/24H
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 60-00-4: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 60 May impair fertility.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 60-00-4: 2
CAS# 77-86-1: 1
CAS# 10043-35-3: 1
Canada
CAS# 60-00-4 is listed on Canadas DSL List.
CAS# 77-86-1 is listed on Canadas DSL List.
CAS# 10043-35-3 is listed on Canadas DSL List.
CAS# 60-00-4 is not listed on Canadas Ingredient Disclosure List.
CAS# 77-86-1 is not listed on Canadas Ingredient Disclosure List.
CAS# 10043-35-3 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 60-00-4 is listed on the TSCA inventory.
CAS# 77-86-1 is listed on the TSCA inventory.
CAS# 10043-35-3 is listed on the TSCA inventory.
