Name:
Urea DNase RNase and Protease free
Synonym:
Carbamide; carbonyldiamide
CAS:
57-13-6
Section 1 - Chemical Product
MSDS Name:Urea DNase RNase and Protease free
Synonym:Carbamide; carbonyldiamide
Synonym:Carbamide; carbonyldiamide
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 57-13-6 | Urea | 200-315-5 |
| Hazard Symbols: None Listed. Risk Phrases: None Listed. |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. Causes redness and pain.
Skin:
May cause skin irritation. Causes redness and pain.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac disturbances. May cause disturbed blood electrolyte balance.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Prolonged or repeated exposure may cause adverse reproductive effects. Prolonged or repeated exposure may cause permanent eye damage. Laboratory experiments have resulted in mutagenic effects.
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. Causes redness and pain.
Skin:
May cause skin irritation. Causes redness and pain.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac disturbances. May cause disturbed blood electrolyte balance.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Prolonged or repeated exposure may cause adverse reproductive effects. Prolonged or repeated exposure may cause permanent eye damage. Laboratory experiments have resulted in mutagenic effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Weak acids such as acetic acid and propionic acid can be used as chemical antidotes, demulcents and stimulants. Treat symptomatically and supportively.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Weak acids such as acetic acid and propionic acid can be used as chemical antidotes, demulcents and stimulants. Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 57-13-6: Russia: 10 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure. Wear impervious gloves.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 57-13-6: Russia: 10 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure. Wear impervious gloves.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystals
Color: white
Odor: ammonia-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 133 - 135 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >132 deg C
Solubility in water: SOLUBLE IN WATER: 1080 G/L (20C)
Specific Gravity/Density:
Molecular Formula: H2NCONH2
Molecular Weight: 60.06
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, temperatures above 130C.
Incompatibilities with Other Materials:
Oxidizing agents, dichromates, nitrates, permanganates, sodium hypochlorite, calcium hypochlorite, chromyl chloride, nitrosyl perchlorate, sodium nitrite, liquid chloride.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide, ammonia.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, temperatures above 130C.
Incompatibilities with Other Materials:
Oxidizing agents, dichromates, nitrates, permanganates, sodium hypochlorite, calcium hypochlorite, chromyl chloride, nitrosyl perchlorate, sodium nitrite, liquid chloride.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide, ammonia.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 57-13-6: YR6250000 LD50/LC50:
CAS# 57-13-6: Oral, mouse: LD50 = 11 gm/kg; Oral, rat: LD50 = 8471 mg/kg.
Carcinogenicity:
Urea - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 57-13-6: YR6250000 LD50/LC50:
CAS# 57-13-6: Oral, mouse: LD50 = 11 gm/kg; Oral, rat: LD50 = 8471 mg/kg.
Carcinogenicity:
Urea - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Daphnia: Daphnia: LC50 >1000mg/LFish Toxicity: Gold Minnow: LC50: >10000 mg/L
Daphnia: Daphnia: LC50 >1000mg/LFish Toxicity: Gold Minnow: LC50: >10000 mg/L
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 57-13-6: 1
Canada
CAS# 57-13-6 is listed on Canadas DSL List.
CAS# 57-13-6 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 57-13-6 is listed on the TSCA inventory.
