Name:
Ethyl acetate
Synonym:
Acetic acid, ethyl ester; Acetic ether; Acetidin; Acetoxyethane; Ethyl acetic ester; Ethyl ethanoate; Vinegar naphtha
CAS:
141-78-6
Section 1 - Chemical Product
MSDS Name:Ethyl acetate
Synonym:Acetic acid, ethyl ester; Acetic ether; Acetidin; Acetoxyethane; Ethyl acetic ester; Ethyl ethanoate; Vinegar naphtha
Synonym:Acetic acid, ethyl ester; Acetic ether; Acetidin; Acetoxyethane; Ethyl acetic ester; Ethyl ethanoate; Vinegar naphtha
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 141-78-6 | Ethyl acetate | >99 | 205-500-4 |
| Hazard Symbols: XI F Risk Phrases: 11 36 66 67 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Irritating to eyes. Repeated exposure may cause skin dryness or cracking. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
Causes eye irritation. Vapors may cause eye irritation.
Skin:
May cause skin irritation. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
May cause irritation of the digestive tract. Ingestion of large amounts may cause central nervous depression. May cause headache, nausea, fatigue, and dizziness.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Inhalation of high concentrations may cause narcotic effects.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation.
Highly flammable. Irritating to eyes. Repeated exposure may cause skin dryness or cracking. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
Causes eye irritation. Vapors may cause eye irritation.
Skin:
May cause skin irritation. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
May cause irritation of the digestive tract. Ingestion of large amounts may cause central nervous depression. May cause headache, nausea, fatigue, and dizziness.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Inhalation of high concentrations may cause narcotic effects.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Water may be ineffective. Use water spray, alcohol foam, CO2, dry chemical.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Water may be ineffective. Use water spray, alcohol foam, CO2, dry chemical.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition.
Provide ventilation. Use only non-sparking tools and equipment.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition.
Provide ventilation. Use only non-sparking tools and equipment.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Wash thoroughly after handling. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 141-78-6: United Kingdom, WEL - TWA: 200 ppm TWA United Kingdom, WEL - STEL: 400 ppm STEL United States OSHA: 400 ppm TWA; 1400 mg/m3 TWA Belgium - TWA: 400 ppm VLE; 1461 mg/m3 VLE France - VME: 400 ppm VME; 1400 mg/m3 VME Germany: 400 ppm TWA; 1500 mg/m3 TWA Japan: 200 ppm OEL; 720 mg/m3 OEL Malaysia: 400 ppm TWA; 1440 mg/m3 TWA Netherlands: 300 ppm STEL; 1100 mg/m3 STEL Netherlands: 150 ppm MAC; 550 mg/m3 MAC Russia: 200 mg/m3 TWA Spain: 400 ppm VLA-ED; 1460 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 141-78-6: United Kingdom, WEL - TWA: 200 ppm TWA United Kingdom, WEL - STEL: 400 ppm STEL United States OSHA: 400 ppm TWA; 1400 mg/m3 TWA Belgium - TWA: 400 ppm VLE; 1461 mg/m3 VLE France - VME: 400 ppm VME; 1400 mg/m3 VME Germany: 400 ppm TWA; 1500 mg/m3 TWA Japan: 200 ppm OEL; 720 mg/m3 OEL Malaysia: 400 ppm TWA; 1440 mg/m3 TWA Netherlands: 300 ppm STEL; 1100 mg/m3 STEL Netherlands: 150 ppm MAC; 550 mg/m3 MAC Russia: 200 mg/m3 TWA Spain: 400 ppm VLA-ED; 1460 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: sweet, fruity odor
pH: Not available.
Vapor Pressure: 73 mm Hg @ 20 deg C
Viscosity: 0.44 cps @ 25 deg C
Boiling Point: 77 deg C
Freezing/Melting Point: -83 deg C
Autoignition Temperature: 426 deg C ( 798.80 deg F)
Flash Point: -4 deg C ( 24.80 deg F)
Explosion Limits, lower: 2.0
Explosion Limits, upper: 11.5
Decomposition Temperature: Not available.
Solubility in water: Slightly soluble.
Specific Gravity/Density: 0.9 (Water=1)
Molecular Formula: C4H8O2
Molecular Weight: 88.11
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Ignition sources, moisture, excess heat, attacks some plastics, rubber, and coatings, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, ethyl alcohol, acetic acid.
Hazardous Polymerization: Will not occur.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Ignition sources, moisture, excess heat, attacks some plastics, rubber, and coatings, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, ethyl alcohol, acetic acid.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 141-78-6: AH5425000 LD50/LC50:
CAS# 141-78-6: Inhalation, mouse: LC50 = 45 gm/m3/2H; Inhalation, rat: LC50 = 200 gm/m3; Oral, mouse: LD50 = 4100 mg/kg; Oral, rabbit: LD50 = 4935 mg/kg; Oral, rat: LD50 = 5620 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
Not available.
Carcinogenicity:
Ethyl acetate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 141-78-6: AH5425000 LD50/LC50:
CAS# 141-78-6: Inhalation, mouse: LC50 = 45 gm/m3/2H; Inhalation, rat: LC50 = 200 gm/m3; Oral, mouse: LD50 = 4100 mg/kg; Oral, rabbit: LD50 = 4935 mg/kg; Oral, rat: LD50 = 5620 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
Not available.
Carcinogenicity:
Ethyl acetate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: 230mg/L; 96HDaphnid LC50=2500 mg/L/96H Golden orfe LC50=270 mg/L/48H
Fish: Fathead Minnow: 230mg/L; 96HDaphnid LC50=2500 mg/L/96H Golden orfe LC50=270 mg/L/48H
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ETHYL ACETATE
Hazard Class: 3
UN Number: 1173
Packing Group: II
IMO
Shipping Name: ETHYL ACETATE
Hazard Class: 3
UN Number: 1173
Packing Group: II
RID/ADR
Shipping Name: ETHYL ACETATE
Hazard Class: 3
UN Number: 1173
Packing group: II
USA RQ: CAS# 141-78-6: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F
Risk Phrases:
R 11 Highly flammable.
R 36 Irritating to eyes.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 141-78-6: 1
Canada
CAS# 141-78-6 is listed on Canadas DSL List.
CAS# 141-78-6 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 141-78-6 is listed on the TSCA inventory.
