Name:
4-Nitroanisole 99+%
Synonym:
1-Methoxy-4-nitrobenzene
CAS:
100-17-4
Section 1 - Chemical Product
MSDS Name:4-Nitroanisole 99+%
Synonym:1-Methoxy-4-nitrobenzene
Synonym:1-Methoxy-4-nitrobenzene
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 100-17-4 | 4-Nitroanisole | >99 | 202-825-3 |
| Hazard Symbols: XN Risk Phrases: 40 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Limited evidence of a carcinogenic effect.
Potential Health Effects
Eye:
May cause eye irritation. May cause eye burns.
Skin:
May cause skin irritation. If absorbed, causes symptoms similar to those of ingestion. May cause skin burns. Effects may be delayed.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Effects may be delayed. May cause respiratory tract irritation.
Chronic:
Not available.
Limited evidence of a carcinogenic effect.
Potential Health Effects
Eye:
May cause eye irritation. May cause eye burns.
Skin:
May cause skin irritation. If absorbed, causes symptoms similar to those of ingestion. May cause skin burns. Effects may be delayed.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Effects may be delayed. May cause respiratory tract irritation.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
For large fires, use water spray, fog, or alcohol-resistant foam.
For small fires, use dry chemical, carbon dioxide, halon, or water spray.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
For large fires, use water spray, fog, or alcohol-resistant foam.
For small fires, use dry chemical, carbon dioxide, halon, or water spray.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Do not get water inside containers.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Do not get water inside containers.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use only in a well-ventilated area.
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use only in a well-ventilated area.
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 100-17-4: Russia: 3 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 100-17-4: Russia: 3 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 260 deg C
Freezing/Melting Point: 54 deg C
Autoignition Temperature: 458 deg C ( 856.40 deg F)
Flash Point: 130 deg C ( 266.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density: 1.2330
Molecular Formula: C7H7NO3
Molecular Weight: 153.14
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 100-17-4: BZ8800000 LD50/LC50:
CAS# 100-17-4: Oral, rat: LD50 = 2300 mg/kg; Skin, rat: LD50 = >16 gm/kg.
Carcinogenicity:
4-Nitroanisole - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 100-17-4: BZ8800000 LD50/LC50:
CAS# 100-17-4: Oral, rat: LD50 = 2300 mg/kg; Skin, rat: LD50 = >16 gm/kg.
Carcinogenicity:
4-Nitroanisole - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Water danger/protection: WGK2 Invertebrate toxicity: EC50 (24 hr) Daphnia magna 13 mg/l (nominal value) [Kuehn, R. et al Water Res.
1989, 23(4), 501-510]
Water danger/protection: WGK2 Invertebrate toxicity: EC50 (24 hr) Daphnia magna 13 mg/l (nominal value) [Kuehn, R. et al Water Res.
1989, 23(4), 501-510]
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: NITROANISOLE, SOLID
Hazard Class: 6.1
UN Number: 2730
Packing Group: III
IMO
Shipping Name: NITROANISOLE, SOLID
Hazard Class: 6.1
UN Number: 2730
Packing Group: III
RID/ADR
Shipping Name: NITROANISOLE
Hazard Class: 6.1
UN Number: 2730
Packing group: III
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 100-17-4: 1
Canada
CAS# 100-17-4 is listed on Canadas NDSL List.
CAS# 100-17-4 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 100-17-4 is listed on the TSCA inventory.
