Name:
Acetonitrile-d3 packaged in 0.5 ml ampules 100.0 atom % D
Synonym:
CAS:
2206-26-0
Section 1 - Chemical Product
MSDS Name:Acetonitrile-d3 packaged in 0.5 ml ampules 100.0 atom % D
Synonym:
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 2206-26-0 | Acetonitrile-d3 | 218-616-5 |
| Hazard Symbols: XN F Risk Phrases: 11 20/21/22 36 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin. May cause dermatitis.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, and death. May cause effects similar to those for inhalation exposure. May cause central nervous system depression.
Inhalation:
Harmful if inhaled. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death.
Causes irritation of mucous membrane. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Causes upper respiratory tract irritation. Inhalation may lead to dizziness, weakness, and drowsiness, leading to stupor, unconsciousness, and even death. Inhalation may lead to hematemesis, convulsions, shock, coma, and possible death.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause liver and kidney damage. May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration. Chronic exposure may cause dizziness, dry throat, sleepiness, anorexia, and nausea.
Highly flammable. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin. May cause dermatitis.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, and death. May cause effects similar to those for inhalation exposure. May cause central nervous system depression.
Inhalation:
Harmful if inhaled. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death.
Causes irritation of mucous membrane. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Causes upper respiratory tract irritation. Inhalation may lead to dizziness, weakness, and drowsiness, leading to stupor, unconsciousness, and even death. Inhalation may lead to hematemesis, convulsions, shock, coma, and possible death.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause liver and kidney damage. May be metabolized to cyanide which in turn acts by inhibiting cytochrome oxidase impairing cellular respiration. Chronic exposure may cause dizziness, dry throat, sleepiness, anorexia, and nausea.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Exposure should be treated as a cyanide poisoning. Effects may be delayed. May be partially metabolized to cyanide in the body. For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood.
Antidote: Always have a cyanide antidote kit on hand when working with cyanide compounds. Get medical advice to use. The combination of sodium thiosulfate and hydroxycobalamin has been used as an effective antidote.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Exposure should be treated as a cyanide poisoning. Effects may be delayed. May be partially metabolized to cyanide in the body. For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood.
Antidote: Always have a cyanide antidote kit on hand when working with cyanide compounds. Get medical advice to use. The combination of sodium thiosulfate and hydroxycobalamin has been used as an effective antidote.
Section 5 - FIRE FIGHTING MEASURES
General Information:
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Flammable liquid and vapor.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide.
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Flammable liquid and vapor.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool.
Provide ventilation.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep from contact with oxidizing materials. Flammables-area. Store protected from moisture.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Keep from contact with oxidizing materials. Flammables-area. Store protected from moisture.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 2206-26-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 2206-26-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Clear liquid
Color: colorless
Odor: aromatic odor - sweetish odor
pH: Not available.
Vapor Pressure: 97 mbar @ 20 deg C
Viscosity: 0.39 cP 20 deg C
Boiling Point: 79-81 deg C @ 760 mmHg
Freezing/Melting Point: -46 deg C
Autoignition Temperature: 525 deg C ( 977.00 deg F)
Flash Point: 2 deg C ( 35.60 deg F)
Explosion Limits, lower: 3.00 vol %
Explosion Limits, upper: 16.00 vol %
Decomposition Temperature:
Solubility in water: Miscible.
Specific Gravity/Density: .8440g/cm3
Molecular Formula: CD3CN
Molecular Weight: 44.0487
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, acids, bases, alkali metals, nitric acid, perchlorates, sulfuric acid, chlorosulfonic acid, oleum, dinitrogen tetraoxide, indium, iodine, sulfur trioxide.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, acids, bases, alkali metals, nitric acid, perchlorates, sulfuric acid, chlorosulfonic acid, oleum, dinitrogen tetraoxide, indium, iodine, sulfur trioxide.
Hazardous Decomposition Products:
Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 2206-26-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Acetonitrile-d3 - Not listed by ACGIH, IARC, or NTP.
CAS# 2206-26-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Acetonitrile-d3 - Not listed by ACGIH, IARC, or NTP.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ACETONITRILE
Hazard Class: 3
UN Number: 1648
Packing Group: II
IMO
Shipping Name: ACETONITRILE
Hazard Class: 3
UN Number: 1648
Packing Group: II
RID/ADR
Shipping Name: ACETONITRILE
Hazard Class: 3
UN Number: 1648
Packing group: II
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN F
Risk Phrases:
R 11 Highly flammable.
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36 Irritating to eyes.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 36/37 Wear suitable protective clothing and
gloves.
WGK (Water Danger/Protection)
CAS# 2206-26-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 2206-26-0 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 2206-26-0 is not listed on the TSCA inventory.
It is for research and development use only.
