Name:
Allylmagnesium bromide 1m solution in diethylether
Synonym:
Diethyl ether; diethyl oxide; ether, ethyl oxide; 1,1-oxybisethane
CAS:
60-29-7
Section 1 - Chemical Product
MSDS Name:Allylmagnesium bromide 1m solution in diethylether
Synonym:Diethyl ether; diethyl oxide; ether, ethyl oxide; 1,1-oxybisethane
Synonym:Diethyl ether; diethyl oxide; ether, ethyl oxide; 1,1-oxybisethane
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 60-29-7 | Ethyl ether | Balance | 200-467-2 |
| Hazard Symbols: XI F+ Risk Phrases: 11 19 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. May form explosive peroxides. Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).Air sensitive.Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation. Causes moderate eye irritation. Causes redness and pain.
Skin:
May cause skin irritation. Harmful if absorbed through the skin.
Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May be absorbed through the skin. Causes severe skin irritation and possible burns.
Ingestion:
Aspiration hazard. May cause irritation of the digestive tract.
Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May be harmful if swallowed. May be harmful if swallowed.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Vapors may cause dizziness or suffocation. May be absorbed through the lungs. Causes irritation of the mucous membrane and upper respiratory tract.
Inhalation may cause irritation of the nose and throat, vomiting, irregular respiration, dizziness, drowsiness, unconsciousness and possible death due to respiratory paralysis.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. May cause kidney damage. Prolonged exposure to high vapor concentrations may cause eye injury.
Highly flammable. May form explosive peroxides. Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).Air sensitive.Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation. Causes moderate eye irritation. Causes redness and pain.
Skin:
May cause skin irritation. Harmful if absorbed through the skin.
Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May be absorbed through the skin. Causes severe skin irritation and possible burns.
Ingestion:
Aspiration hazard. May cause irritation of the digestive tract.
Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May be harmful if swallowed. May be harmful if swallowed.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Vapors may cause dizziness or suffocation. May be absorbed through the lungs. Causes irritation of the mucous membrane and upper respiratory tract.
Inhalation may cause irritation of the nose and throat, vomiting, irregular respiration, dizziness, drowsiness, unconsciousness and possible death due to respiratory paralysis.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. May cause kidney damage. Prolonged exposure to high vapor concentrations may cause eye injury.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Possible aspiration hazard. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat symptomatically and supportively.
Skin:
Get medical aid immediately. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Possible aspiration hazard. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
May be ignited by heat, sparks, and flame. Will be easily ignited by heat, sparks or flame. Containers may explode when heated. May re-ignite after fire is extinguished.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
May be ignited by heat, sparks, and flame. Will be easily ignited by heat, sparks or flame. Containers may explode when heated. May re-ignite after fire is extinguished.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not ingest or inhale. Store protected from light. Handle under an inert atmosphere. Store protected from air. If peroxide formation is suspected, do not open or move container. Do not use if the material has evaporated to dryness. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Keep refrigerated. (Store below 4C/39F.) Do not expose to air. Store protected from moisture. Store protected from light. Store under an inert atmosphere. Keep away from oxidizing agents.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not ingest or inhale. Store protected from light. Handle under an inert atmosphere. Store protected from air. If peroxide formation is suspected, do not open or move container. Do not use if the material has evaporated to dryness. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Keep refrigerated. (Store below 4C/39F.) Do not expose to air. Store protected from moisture. Store protected from light. Store under an inert atmosphere. Keep away from oxidizing agents.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 60-29-7: United Kingdom, WEL - TWA: 100 ppm TWA; 310 mg/m3 TWA United Kingdom, WEL - STEL: 200 ppm STEL; 620 mg/m3 STEL United States OSHA: 400 ppm TWA; 1200 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 308 mg/m3 VLE Belgium - STEL: 200 ppm VLE; 616 mg/m3 VLE France - VME: 400 ppm VME; 1200 mg/m3 VME France - VLE: 500 ppm VLE; 1500 mg/m3 VLE Germany: 400 ppm TWA; 1200 mg/m3 TWA Japan: 400 ppm OEL; 1200 mg/m3 OEL Malaysia: 400 ppm TWA; 1210 mg/m3 TWA Netherlands: 200 ppm STEL; 616 mg/m3 STEL Netherlands: 100 ppm MAC; 308 mg/m3 MAC Russia: 300 mg/m3 TWA Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 616 mg/m3 VLA-EC CAS# 1730-25-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 60-29-7: United Kingdom, WEL - TWA: 100 ppm TWA; 310 mg/m3 TWA United Kingdom, WEL - STEL: 200 ppm STEL; 620 mg/m3 STEL United States OSHA: 400 ppm TWA; 1200 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 308 mg/m3 VLE Belgium - STEL: 200 ppm VLE; 616 mg/m3 VLE France - VME: 400 ppm VME; 1200 mg/m3 VME France - VLE: 500 ppm VLE; 1500 mg/m3 VLE Germany: 400 ppm TWA; 1200 mg/m3 TWA Japan: 400 ppm OEL; 1200 mg/m3 OEL Malaysia: 400 ppm TWA; 1210 mg/m3 TWA Netherlands: 200 ppm STEL; 616 mg/m3 STEL Netherlands: 100 ppm MAC; 308 mg/m3 MAC Russia: 300 mg/m3 TWA Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 616 mg/m3 VLA-EC CAS# 1730-25-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: Color (apha):10 max
Odor: Sweet, aromatic.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: 356 deg F ( 180.00 deg C)
Flash Point: -49 deg F ( -45.00 deg C)
Explosion Limits, lower: 1.9
Explosion Limits, upper: 36.0
Decomposition Temperature: Not available.
Solubility in water: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C3H5BrMg
Molecular Weight: 145.244
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Not stable during routine use and handling conditions. Prolonged exposure to air and sunlight may form unstable peroxides. Has not been fully evaluated.
Conditions to Avoid:
Incompatible materials, light, ignition sources, exposure to air, excess heat, strong acids, exposure to moist air or water, oxidizers.
Incompatibilities with Other Materials:
Strong oxidizing agents, bromine trifluoride, chlorine trifluoride, halogens, nitric acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen peroxides, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate, moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid, peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, peroxides, bromine fumes.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures. Not stable during routine use and handling conditions. Prolonged exposure to air and sunlight may form unstable peroxides. Has not been fully evaluated.
Conditions to Avoid:
Incompatible materials, light, ignition sources, exposure to air, excess heat, strong acids, exposure to moist air or water, oxidizers.
Incompatibilities with Other Materials:
Strong oxidizing agents, bromine trifluoride, chlorine trifluoride, halogens, nitric acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen peroxides, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate, moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid, peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, peroxides, bromine fumes.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 60-29-7: KI5775000 CAS# 1730-25-2 unlisted.
LD50/LC50:
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, mouse: LD50 = 1760 mg/kg; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 1730-25-2.
Carcinogenicity:
Ethyl ether - Not listed by ACGIH, IARC, or NTP.
Allylmagnesium bromide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 60-29-7: KI5775000 CAS# 1730-25-2 unlisted.
LD50/LC50:
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, mouse: LD50 = 1760 mg/kg; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 1730-25-2.
Carcinogenicity:
Ethyl ether - Not listed by ACGIH, IARC, or NTP.
Allylmagnesium bromide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox testIf ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox testIf ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 60-29-7: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F+
Risk Phrases:
R 11 Highly flammable.
R 19 May form explosive peroxides.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 60-29-7: 1
CAS# 1730-25-2: No information available.
Canada
CAS# 60-29-7 is listed on Canadas DSL List.
CAS# 60-29-7 is listed on Canadas Ingredient Disclosure List.
CAS# 1730-25-2 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 60-29-7 is listed on the TSCA inventory.
CAS# 1730-25-2 is not listed on the TSCA inventory.
It is for research and development use only.
