Name:
Ammonia-Ammonium Chloride Buffer Solution
Synonym:
Non
CAS:
7664-41-7
Section 1 - Chemical Product
MSDS Name:Ammonia-Ammonium Chloride Buffer Solution
Synonym:Non
Synonym:Non
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 7664-41-7 | Ammonia | 57 | 231-635-3 |
| Hazard Symbols: C Risk Phrases: 34 37 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns. Irritating to respiratory system.Corrosive.
Potential Health Effects
Eye:
Contact with liquid or vapor causes severe burns and possible irreversible eye damage. May cause temporary blindness.
Skin:
Causes skin burns. May cause frostbite. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes severe digestive tract burns with abdominal pain, vomiting, and possible death.
Inhalation:
Causes chemical burns to the respiratory tract. Inhalation of high concentrations of ammonia vapors may cause shortness of breath, bronchospasm, chest pain and pulmonary edema which may be fatal.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.
Causes burns. Irritating to respiratory system.Corrosive.
Potential Health Effects
Eye:
Contact with liquid or vapor causes severe burns and possible irreversible eye damage. May cause temporary blindness.
Skin:
Causes skin burns. May cause frostbite. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes severe digestive tract burns with abdominal pain, vomiting, and possible death.
Inhalation:
Causes chemical burns to the respiratory tract. Inhalation of high concentrations of ammonia vapors may cause shortness of breath, bronchospasm, chest pain and pulmonary edema which may be fatal.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation. Effects may be delayed. Laboratory experiments have resulted in mutagenic effects.
Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney, or respiratory function may be more susceptible to the effects of this substance. Treat symptomatically and supportively.
Antidote: No specific antidote exists.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney, or respiratory function may be more susceptible to the effects of this substance. Treat symptomatically and supportively.
Antidote: No specific antidote exists.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. This product may be under pressure; cool before opening.
Discard contaminated shoes.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. This product may be under pressure; cool before opening.
Discard contaminated shoes.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 7664-41-7: United Kingdom, WEL - TWA: 25 ppm TWA (anhydrous); 18 mg/m3 TWA (anhydrous) United Kingdom, WEL - STEL: 35 ppm STEL (anhydrous); 25 mg/m3 STE (anhydrous) United States OSHA: 50 ppm TWA; 35 mg/m3 TWA Belgium - TWA: 20 ppm VLE; 14 mg/m3 VLE Belgium - STEL: 50 ppm VLE; 36 mg/m3 VLE France - VME: 25 ppm VME; 18 mg/m3 VME France - VLE: 50 ppm VLE; 36 mg/m3 VLE Germany: 50 ppm TWA; 35 mg/m3 TWA Japan: 25 ppm OEL; 17 mg/m3 OEL Malaysia: 25 ppm TWA; 17 mg/m3 TWA Netherlands: 50 ppm STEL; 36 mg/m3 STEL Netherlands: 20 ppm MAC; 14 mg/m3 MAC Russia: 20 mg/m3 TWA Spain: 20 ppm VLA-ED; 14 mg/m3 VLA-ED Spain: 50 ppm VLA-EC; 36 mg/m3 VLA-EC CAS# 7732-18-5: CAS# 12125-02-9: United Kingdom, WEL - TWA: 10 mg/m3 TWA (fume) United Kingdom, WEL - STEL: 20 mg/m3 STEL (fume) Belgium - TWA: 10 mg/m3 VLE (fumes) Belgium - STEL: 20 mg/m3 VLE (fumes) France - VME: 10 mg/m3 VME (fume) Malaysia: 10 mg/m3 TWA (fume) Netherlands: 10 mg/m3 MAC (smoke) Russia: 10 mg/m3 TWA (fumes) Spain: 10 mg/m3 VLA-ED (fume) Spain: 20 mg/m3 VLA-EC (fume) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 7664-41-7: United Kingdom, WEL - TWA: 25 ppm TWA (anhydrous); 18 mg/m3 TWA (anhydrous) United Kingdom, WEL - STEL: 35 ppm STEL (anhydrous); 25 mg/m3 STE (anhydrous) United States OSHA: 50 ppm TWA; 35 mg/m3 TWA Belgium - TWA: 20 ppm VLE; 14 mg/m3 VLE Belgium - STEL: 50 ppm VLE; 36 mg/m3 VLE France - VME: 25 ppm VME; 18 mg/m3 VME France - VLE: 50 ppm VLE; 36 mg/m3 VLE Germany: 50 ppm TWA; 35 mg/m3 TWA Japan: 25 ppm OEL; 17 mg/m3 OEL Malaysia: 25 ppm TWA; 17 mg/m3 TWA Netherlands: 50 ppm STEL; 36 mg/m3 STEL Netherlands: 20 ppm MAC; 14 mg/m3 MAC Russia: 20 mg/m3 TWA Spain: 20 ppm VLA-ED; 14 mg/m3 VLA-ED Spain: 50 ppm VLA-EC; 36 mg/m3 VLA-EC CAS# 7732-18-5: CAS# 12125-02-9: United Kingdom, WEL - TWA: 10 mg/m3 TWA (fume) United Kingdom, WEL - STEL: 20 mg/m3 STEL (fume) Belgium - TWA: 10 mg/m3 VLE (fumes) Belgium - STEL: 20 mg/m3 VLE (fumes) France - VME: 10 mg/m3 VME (fume) Malaysia: 10 mg/m3 TWA (fume) Netherlands: 10 mg/m3 MAC (smoke) Russia: 10 mg/m3 TWA (fumes) Spain: 10 mg/m3 VLA-ED (fume) Spain: 20 mg/m3 VLA-EC (fume) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: Pungent odor.
pH: Not available.
Vapor Pressure: 330 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Miscible.
Specific Gravity/Density: 0.93
Molecular Formula: Mixture
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, ammonium persulfate, acid chlorides, ammonium nitrate, bromine trifluoride, chlorine trifluoride, copper, ethylene oxide, galvanized iron, halogens, nitric acid, potassium chlorates, zinc, silver salts, hydrogen peroxides, acid anhydrides, chromium trioxide, chromyl chloride, calcium, nitrogen dioxide, alkalies, carbonates, bromine pentafluoride, interhalogens, chloroformates, 2,4-dinitrochlorobenzene, 4-chloronitrobenzene, boron halides, magnesium perchlorate, lead salts, heavy metal salts, tin, hydrogen cyanide, chloroformamideium nitrate, nitrogen trichloride, oxygen + platinum, tellurium tetrabromide, tellurium tetrachloride, thiotrithiazyl chloride, 2-chloronitrobenzene, stibine, tetramethylammonium amide, thicarbonyl azide thiocyanate, nitryl chloride, dichlorine oxide, trioxygen difluoride, nitric oxide, pentaborane.
Hazardous Decomposition Products:
Hydrogen chloride, irritating and toxic fumes and gases, nitrogen oxides (NOx) and ammonia (NH3).
Hazardous Polymerization: Has not been reported
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, ammonium persulfate, acid chlorides, ammonium nitrate, bromine trifluoride, chlorine trifluoride, copper, ethylene oxide, galvanized iron, halogens, nitric acid, potassium chlorates, zinc, silver salts, hydrogen peroxides, acid anhydrides, chromium trioxide, chromyl chloride, calcium, nitrogen dioxide, alkalies, carbonates, bromine pentafluoride, interhalogens, chloroformates, 2,4-dinitrochlorobenzene, 4-chloronitrobenzene, boron halides, magnesium perchlorate, lead salts, heavy metal salts, tin, hydrogen cyanide, chloroformamideium nitrate, nitrogen trichloride, oxygen + platinum, tellurium tetrabromide, tellurium tetrachloride, thiotrithiazyl chloride, 2-chloronitrobenzene, stibine, tetramethylammonium amide, thicarbonyl azide thiocyanate, nitryl chloride, dichlorine oxide, trioxygen difluoride, nitric oxide, pentaborane.
Hazardous Decomposition Products:
Hydrogen chloride, irritating and toxic fumes and gases, nitrogen oxides (NOx) and ammonia (NH3).
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7664-41-7: BO0875000 CAS# 7732-18-5: ZC0110000 CAS# 12125-02-9: BP4550000 BP4570000 LD50/LC50:
CAS# 7664-41-7: Inhalation, mouse: LC50 = 4230 ppm/1H; Inhalation, mouse: LC50 = 4600 mg/m3/2H; Inhalation, rabbit: LC50 = 7 gm/m3/1H; Inhalation, rat: LC50 = 2000 ppm/4H; Inhalation, rat: LC50 = 18600 mg/m3/5M; Inhalation, rat: LC50 = 7040 mg/m3/30M; Skin, rat: LD50 = 112000 mg/m3/15M; Skin, rat: LD50 = 71900 mg/m3/30M; Skin, rat: LD50 = 4840 mg/m3/60M.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 12125-02-9: Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, eye: 100 mg Severe; Oral, mouse: LD50 = 1300 mg/kg; Oral, rat: LD50 = 1650 mg/kg.
Carcinogenicity:
Ammonia - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Ammonium chloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 7664-41-7: BO0875000 CAS# 7732-18-5: ZC0110000 CAS# 12125-02-9: BP4550000 BP4570000 LD50/LC50:
CAS# 7664-41-7: Inhalation, mouse: LC50 = 4230 ppm/1H; Inhalation, mouse: LC50 = 4600 mg/m3/2H; Inhalation, rabbit: LC50 = 7 gm/m3/1H; Inhalation, rat: LC50 = 2000 ppm/4H; Inhalation, rat: LC50 = 18600 mg/m3/5M; Inhalation, rat: LC50 = 7040 mg/m3/30M; Skin, rat: LD50 = 112000 mg/m3/15M; Skin, rat: LD50 = 71900 mg/m3/30M; Skin, rat: LD50 = 4840 mg/m3/60M.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 12125-02-9: Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, eye: 100 mg Severe; Oral, mouse: LD50 = 1300 mg/kg; Oral, rat: LD50 = 1650 mg/kg.
Carcinogenicity:
Ammonia - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Ammonium chloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Goldfish: LC60 = 2.0-2.5 ppm; 1-4 days; CAS# 7664-41-7: UnspecifiedFish: Rainbow trout: TLm = 0.41 ppm; 48 Hr; CAS# 7664-41-7: Continuous flowFish: Fathead Minnow: TLm = 8.2 ppm; 96 Hr; CAS# 7664-41-7: UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 2.0 mg/L; 5 min.; CAS# 7664-41-7: Microtox test @ 15CCAS# 7664-41-7: Ammonia is strongly adsorbed on soil, and on sediment particles and colloids in water. This adsorption results in high concentrations of sorbed ammonia in oxidized sediments. Under anoxic conditions, the adsorptive capacity of sediments is less, resulting in the release of ammonia to either the water column or an oxidized
Fish: Goldfish: LC60 = 2.0-2.5 ppm; 1-4 days; CAS# 7664-41-7: UnspecifiedFish: Rainbow trout: TLm = 0.41 ppm; 48 Hr; CAS# 7664-41-7: Continuous flowFish: Fathead Minnow: TLm = 8.2 ppm; 96 Hr; CAS# 7664-41-7: UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 2.0 mg/L; 5 min.; CAS# 7664-41-7: Microtox test @ 15CCAS# 7664-41-7: Ammonia is strongly adsorbed on soil, and on sediment particles and colloids in water. This adsorption results in high concentrations of sorbed ammonia in oxidized sediments. Under anoxic conditions, the adsorptive capacity of sediments is less, resulting in the release of ammonia to either the water column or an oxidized
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: AMMONIA SOLUTION
Hazard Class: 8
UN Number: 2672
Packing Group: III
IMO
Shipping Name: AMMONIA SOLUTION
Hazard Class: 8
UN Number: 2672
Packing Group: III
RID/ADR
Shipping Name: AMMONIA SOLUTION
Hazard Class: 8
UN Number: 2672
Packing group: III
USA RQ: CAS# 7664-41-7: 100 lb final RQ; 45.4 kg final RQ
USA RQ: CAS# 12125-02-9: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
R 37 Irritating to respiratory system.
Safety Phrases:
S 7 Keep container tightly closed.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
WGK (Water Danger/Protection)
CAS# 7664-41-7: 2
CAS# 7732-18-5: No information available.
CAS# 12125-02-9: 1
Canada
CAS# 7664-41-7 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 12125-02-9 is listed on Canadas DSL List.
CAS# 7664-41-7 is listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 12125-02-9 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7664-41-7 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 12125-02-9 is listed on the TSCA inventory.
