Name:
Aniline 99.8%
Synonym:
Aminobenzene; Aminophen; Aniline oil; Benzenamine; Benzene, amino; Phenylamin
CAS:
62-53-3
Section 1 - Chemical Product
MSDS Name:Aniline 99.8%
Synonym:Aminobenzene; Aminophen; Aniline oil; Benzenamine; Benzene, amino; Phenylamin
Synonym:Aminobenzene; Aminophen; Aniline oil; Benzenamine; Benzene, amino; Phenylamin
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 62-53-3 | Aniline | 99.8 | 200-539-3 |
| Hazard Symbols: T N Risk Phrases: 20/21/22 40 48/23/24/25 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Possible risks of irreversible effects. Toxic : danger of serious damage to health by prolonged exposure through inhalation, contact with skin and if swallowed.Combustible liquid.Hygroscopic.Light sensitive.Dangerous for the environment.
Potential Health Effects
Eye:
Causes severe eye irritation. May cause lacrimation (tearing), blurred vision, and photophobia. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes moderate skin irritation. Harmful if absorbed through the skin. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause effects similar to those of acute inhalation. May cause central nervous system depression, convulsions, coma, and possible death due to respiratory paralysis.
May cause cardiac effects such as heart blocks, arrhythmias, shock and possible death due to cardiovascular collapse.
Inhalation:
Effects may be delayed. Causes respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea (labored breathing), and death. Aspiration may lead to pulmonary edema.
Chronic:
May cause liver and kidney damage. May cause fetal effects. Repeated exposure may cause sensitization dermatitis. Chronic exposure may cause hemolysis of the red blood cells followed by stimulation of the bone marrow. Laboratory experiments have resulted in mutagenic effects. May cause cyanosis - a blue-gray coloring of the skin and lips caused by a lack of oxygen. Animal studies have reported the development of tumors.
Harmful by inhalation, in contact with skin and if swallowed.
Possible risks of irreversible effects. Toxic : danger of serious damage to health by prolonged exposure through inhalation, contact with skin and if swallowed.Combustible liquid.Hygroscopic.Light sensitive.Dangerous for the environment.
Potential Health Effects
Eye:
Causes severe eye irritation. May cause lacrimation (tearing), blurred vision, and photophobia. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes moderate skin irritation. Harmful if absorbed through the skin. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause effects similar to those of acute inhalation. May cause central nervous system depression, convulsions, coma, and possible death due to respiratory paralysis.
May cause cardiac effects such as heart blocks, arrhythmias, shock and possible death due to cardiovascular collapse.
Inhalation:
Effects may be delayed. Causes respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea (labored breathing), and death. Aspiration may lead to pulmonary edema.
Chronic:
May cause liver and kidney damage. May cause fetal effects. Repeated exposure may cause sensitization dermatitis. Chronic exposure may cause hemolysis of the red blood cells followed by stimulation of the bone marrow. Laboratory experiments have resulted in mutagenic effects. May cause cyanosis - a blue-gray coloring of the skin and lips caused by a lack of oxygen. Animal studies have reported the development of tumors.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation. Cleansing of the entire contaminated area of the body is of utmost importance. Do not administer alcohol in any form. Individuals with liver or kidney disorders, impaired cardiovascular status, or a history of alcoholism may be more susceptible to the effects of this product.
Effects may be delayed. If cyanosis is severe, intravenous injection of Methylene blue, 1mg/kg of body weight may be of value.
Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Absorption of this product into the body may cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation. Cleansing of the entire contaminated area of the body is of utmost importance. Do not administer alcohol in any form. Individuals with liver or kidney disorders, impaired cardiovascular status, or a history of alcoholism may be more susceptible to the effects of this product.
Effects may be delayed. If cyanosis is severe, intravenous injection of Methylene blue, 1mg/kg of body weight may be of value.
Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use extinguishing media most appropriate for the surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Containers may explode when heated.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use extinguishing media most appropriate for the surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Store protected from light. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep away from acids. Material darkens in color on storage. Store protected from moisture. Store protected from light.
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Store protected from light. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep away from acids. Material darkens in color on storage. Store protected from moisture. Store protected from light.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use only under a chemical fume hood.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Use only under a chemical fume hood.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: oily liquid - colorless liquid
Odor: amine-like - characteristic odor
pH: 8.1
Vapor Pressure: 0.49 mm Hg @ 20 deg C
Viscosity: 4.435 cp @ 20 deg C
Boiling Point: 184 deg C @ 760.00 mmHg
Freezing/Melting Point: -6 deg C
Autoignition Temperature: 615 deg C ( 1,139.00 deg F)
Flash Point: 70 deg C ( 158.00 deg F)
Explosion Limits, lower: 1.30 vol %
Explosion Limits, upper: 20.00 vol %
Decomposition Temperature:
Solubility in water: IN WATER: 0.3 G/L (20C)
Specific Gravity/Density: 1.0216g/cm3
Molecular Formula: C6H7N
Molecular Weight: 93.13
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Volatile in steam.
Sensitive to light. May discolor on exposure to air and light.
Conditions to Avoid:
Incompatible materials, light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, bases, aluminum, fluorine, formaldehyde, iron, nitric acid, silver perchlorate, sodium peroxide, sulfuric acid, zinc, hydrogen peroxides, ozone, acid anhydrides, chlorosulfonic acid, oleum, perchromates, nitromethane, dibenzoyl peroxide, benzenediazonium-2-carboxylate, boron trichloride, tetranitromethane, trichloronitromethane, diisopropyl peroxydicarbonate, hexachloromelamine, peroxomonosulfuric acid, albumin, iron salts, perchloric acid, nitrobenzene, alkalis, moisture, potassium peroxide, glycerine, fuming nitric acid, N-chloro compounds, N-bromoimides (e.g. n-bromosuccinimide), peroxydisulfuric acid, nitrosyl fluoride, toluene diisocyanate.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures. Volatile in steam.
Sensitive to light. May discolor on exposure to air and light.
Conditions to Avoid:
Incompatible materials, light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, bases, aluminum, fluorine, formaldehyde, iron, nitric acid, silver perchlorate, sodium peroxide, sulfuric acid, zinc, hydrogen peroxides, ozone, acid anhydrides, chlorosulfonic acid, oleum, perchromates, nitromethane, dibenzoyl peroxide, benzenediazonium-2-carboxylate, boron trichloride, tetranitromethane, trichloronitromethane, diisopropyl peroxydicarbonate, hexachloromelamine, peroxomonosulfuric acid, albumin, iron salts, perchloric acid, nitrobenzene, alkalis, moisture, potassium peroxide, glycerine, fuming nitric acid, N-chloro compounds, N-bromoimides (e.g. n-bromosuccinimide), peroxydisulfuric acid, nitrosyl fluoride, toluene diisocyanate.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 62-53-3: BW6650000 LD50/LC50:
CAS# 62-53-3: Dermal, guinea pig: LD50 = 1290 mg/kg; Draize test, rabbit, eye: 102 mg Severe; Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 175 ppm/7H; Oral, mouse: LD50 = 464 mg/kg; Oral, rat: LD50 = 250 mg/kg; Skin, rabbit: LD50 = 820 uL/kg; Skin, rat: LD50 = 1400 mg/kg.
Carcinogenicity:
Aniline - ACGIH: A3 - Animal Carcinogen California: carcinogen; initial date 1/1/90 NIOSH: occupational carcinogen IARC: Group 3 carcinogen Other:
See actual entry in RTECS for complete information.
CAS# 62-53-3: BW6650000 LD50/LC50:
CAS# 62-53-3: Dermal, guinea pig: LD50 = 1290 mg/kg; Draize test, rabbit, eye: 102 mg Severe; Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 175 ppm/7H; Oral, mouse: LD50 = 464 mg/kg; Oral, rat: LD50 = 250 mg/kg; Skin, rabbit: LD50 = 820 uL/kg; Skin, rat: LD50 = 1400 mg/kg.
Carcinogenicity:
Aniline - ACGIH: A3 - Animal Carcinogen California: carcinogen; initial date 1/1/90 NIOSH: occupational carcinogen IARC: Group 3 carcinogen Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Water flea Daphnia: LC50 = 0.10 mg/L; 48 Hr; UnspecifiedFish: Rainbow trout: LC50 = 8.2 mg/L; Max. exposure = 7 days; UnspecifiedFish: Bluegill/Sunfish: 1020 ppm; 1 Hr; UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 425-488 mg/L; 5,15 min; Microtox test at 14.9-15.1C Other Dangerous to aquatic life in high concentrations.
Water flea Daphnia: LC50 = 0.10 mg/L; 48 Hr; UnspecifiedFish: Rainbow trout: LC50 = 8.2 mg/L; Max. exposure = 7 days; UnspecifiedFish: Bluegill/Sunfish: 1020 ppm; 1 Hr; UnspecifiedBacteria: Phytobacterium phosphoreum: EC50 = 425-488 mg/L; 5,15 min; Microtox test at 14.9-15.1C Other Dangerous to aquatic life in high concentrations.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing Group: II
IMO
Shipping Name: ANILINE
Hazard Class: 6.1
UN Number: 1547
Packing Group: II
RID/ADR
Shipping Name: ANILINE
Dangerous Goods Code: 6.1(12B)
UN Number: 1547
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 40 Possible risks of irreversible effects.
R 48/23/24/25 Toxic : danger of serious damage to
health by prolonged exposure through inhalation,
contact with skin and if swallowed.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 62-53-3: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 62-53-3 is listed on Canadas DSL List.
CAS# 62-53-3 is listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 62-53-3: OEL-ARAB Republic of Egypt:TWA 2 ppm (10 mg/m3);Skin
OEL-AUSTRALIA:TWA 2 ppm (10 mg/m3);Skin
OEL-AUSTRIA:TWA 2 ppm (8 mg/m3);Skin
OEL-BELGIUM:TWA 2 ppm (7.6 mg/m3);Skin
OEL-CZECHOSLOVAKIA:TWA 5 mg/m3;STEL 20 mg/m3 JAN9
OEL-DENMARK:TWA 1 ppm (4 mg/m3);Skin
OEL-FINLAND:TWA 2 ppm (7.6 mg/m3);STEL 4 ppm (15 mg/m3);Skin;CAR
OEL-FRANCE:TWA 2 ppm (10 mg/m3);Skin
OEL-GERMANY:TWA 2 ppm (8 mg/m3);Skin;Carcinogen
OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3;Skin
OEL-INDIA:TWA 0.2 mg/m3;Skin
OEL-JAPAN:TWA 1 ppm (3.8 mg/m3);Skin
OEL-THE NETHERLANDS:TWA 5 ppm (19 mg/m3);Skin
OEL-THE PHILIPPINES:TWA 5 ppm (19 mg/m3);Skin
OEL-POLAND:TWA 5 mg/m3;STEL 20 mg/m3;Skin
OEL-RUSSIA:TWA 1 ppm;STEL 0.1 mg/m3;Skin
OEL-SWEDEN:TWA 1 ppm (4 mg/m3);STEL 2 ppm (8 mg/m3);Skin
OEL-SWITZERLAND:TWA 2 ppm (8 mg/m3);STEL 10 ppm (40 mg/m3);Skin
OEL-TURKEY:TWA 5 ppm (19 mg/m3);Skin
OEL-UNITED KINGDOM:TWA 2 ppm (10 mg/m3);STEL 5 ppm;Skin
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 62-53-3 is listed on the TSCA inventory.
