MSDS Name:Atropine 99%
Synonym:DL-Hyoscyamine; Alpha-(Hydroxymethyl)Benzeneacetic Acid; 8-Methyl-8-Azabicyclo-(3.2.1)Oct-3-yl Ester

EMERGENCY OVERVIEW
Very toxic by inhalation and if swallowed.Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation. May cause lacrimation (tearing), blurred vision, and photophobia.
Skin:
May cause skin irritation. May cause skin rash and eruptions.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Ingestion of large amounts may cause pain, constipation or diarrhea.
Human fatalities have been reported from acute poisoning. May cause an abrupt rise in body temperature, convulsions, and coma. Ingestion may cause headache, nausea, and vomiting.
Inhalation:
May cause respiratory tract irritation. May cause cardiovascular disturbances, hearing abnormalities, central nervous system depression, muscle weakness, and possible death due to respiratory failure.
Chronic:
Adverse reproductive effects have been reported in humans. Exposure to large doses may cause central nervous system depression.

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Store protected from light.

Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 51-55-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Physical State: Crystalline powder
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 114.00 - 118.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 1g/455 ml
Specific Gravity/Density:
Molecular Formula: C17H23NO3
Molecular Weight: 289.36

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

RTECS#:
CAS# 51-55-8: CK0700000 LD50/LC50:
CAS# 51-55-8: Oral, mouse: LD50 = 75 mg/kg; Oral, rabbit: LD50 = 600 mg/kg; Oral, rat: LD50 = 500 mg/kg.
Carcinogenicity:
Atropine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Dispose of in a manner consistent with federal, state, and local regulations.

IATA
Shipping Name: ALKALOIDS, SOLID, N.O.S.*
Hazard Class: 6.1
UN Number: 1544
Packing Group: I
IMO
Shipping Name: ALKALOIDS, SOLID, N.O.S.
Hazard Class: 6.1
UN Number: 1544
Packing Group: I
RID/ADR
Shipping Name: ALKALOIDS, SOLID, N.O.S.
Hazard Class: 6.1
UN Number: 1544
Packing group: I

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26/28 Very toxic by inhalation and if swallowed.
Safety Phrases:
S 1 Keep locked up.
S 25 Avoid contact with eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 51-55-8: 3
Canada
CAS# 51-55-8 is listed on Canadas NDSL List.
CAS# 51-55-8 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 51-55-8 is listed on the TSCA inventory.