Name:
Borane-tetrahydrofuran complex 1M solution in tetrahydrofuran
Synonym:
Trihydro(tetrahydrofuran)boron in THF
CAS:
109-99-9
Section 1 - Chemical Product
MSDS Name:Borane-tetrahydrofuran complex 1M solution in tetrahydrofuran
Synonym:Trihydro(tetrahydrofuran)boron in THF
Synonym:Trihydro(tetrahydrofuran)boron in THF
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 109-99-9 | Tetrahydrofuran | 91 | 203-726-8 |
| Hazard Symbols: XI F Risk Phrases: 11 15 19 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Contact with water liberates extremely flammable gases. May form explosive peroxides. Irritating to eyes, respiratory system and skin.Water-reactive.Moisture sensitive.Stench.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause irritation of the digestive tract. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
May cause headache. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May cause effects similar to those described for ingestion. May be harmful if inhaled. Exposure to high concentrations may produce narcosis, nausea and loss of consciousness.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis.
Highly flammable. Contact with water liberates extremely flammable gases. May form explosive peroxides. Irritating to eyes, respiratory system and skin.Water-reactive.Moisture sensitive.Stench.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause irritation of the digestive tract. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
May cause headache. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May cause effects similar to those described for ingestion. May be harmful if inhaled. Exposure to high concentrations may produce narcosis, nausea and loss of consciousness.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Reacts violently with water giving off flammable gas which may explode. Extremely flammable liquid and vapor. This substance reacts with water to form gases which might cause closed containers to rupture. Will be easily ignited by heat, sparks or flame. Vapors may form an explosive mixture with air. Containers may explode when heated. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use dry chemical to fight fire. DO NOT USE WATER!
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Reacts violently with water giving off flammable gas which may explode. Extremely flammable liquid and vapor. This substance reacts with water to form gases which might cause closed containers to rupture. Will be easily ignited by heat, sparks or flame. Vapors may form an explosive mixture with air. Containers may explode when heated. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use dry chemical to fight fire. DO NOT USE WATER!
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Approach spill from upwind.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Approach spill from upwind.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Container should be opened by a technically qualified person. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Avoid breathing vapor.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a dry area.
Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator/flammables.
Regularly check inhibitor levels to maintain peroxide levels below 1%. After opening, purge container with nitrogen before reclosing.
Periodically test for peroxide formation on long-term storage.
Addition of water or appropriate reducing materials will lessen peroxide formation. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Container should be opened by a technically qualified person. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Avoid breathing vapor.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a dry area.
Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator/flammables.
Regularly check inhibitor levels to maintain peroxide levels below 1%. After opening, purge container with nitrogen before reclosing.
Periodically test for peroxide formation on long-term storage.
Addition of water or appropriate reducing materials will lessen peroxide formation. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 14044-65-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 14044-65-6: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: Stench.
pH: Not available.
Vapor Pressure: 145 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 66 deg C
Freezing/Melting Point: -108 deg C
Autoignition Temperature: 321 deg F ( 160.56 deg C)
Flash Point: -17 deg C ( 1.40 deg F)
Explosion Limits, lower: 2.0%
Explosion Limits, upper: 11.8%
Decomposition Temperature:
Solubility in water: reacts
Specific Gravity/Density: .8980g/cm3
Molecular Formula: C4H11BO
Molecular Weight: 85.94
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Unstable. This material may be sensitive to peroxide formation.
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
High temperatures, mechanical shock, incompatible materials, ignition sources, moisture, contact with water, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Acids, acid chlorides, acid anhydrides, oxidizing agents, alcohols, and water.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of boron, borane, hydrogen gas.
Hazardous Polymerization: May occur.
Unstable. This material may be sensitive to peroxide formation.
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
High temperatures, mechanical shock, incompatible materials, ignition sources, moisture, contact with water, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Acids, acid chlorides, acid anhydrides, oxidizing agents, alcohols, and water.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, oxides of boron, borane, hydrogen gas.
Hazardous Polymerization: May occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 109-99-9: LU5950000 CAS# 14044-65-6 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 14044-65-6.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Borane-tetrahydrofuran complex - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 109-99-9: LU5950000 CAS# 14044-65-6 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 14044-65-6.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Borane-tetrahydrofuran complex - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Cas# 109-00-0: LC50(96Hr.) Fathead Minnow = 2160 mg/L
Cas# 109-00-0: LC50(96Hr.) Fathead Minnow = 2160 mg/L
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ORGANOMETALLIC COMPOUND, WATER-REACTIVE, FLAMMABLE
, N.O.S.*
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: II
IMO
Shipping Name: ORGANOMETALLIC COMPOUND, WATER-REACTIVE, FLAMMABLE
, N.O.S.
Hazard Class: 4.3
UN Number: 3207
Packing Group: II
RID/ADR
Shipping Name: ORGANOMETALLIC COMPOUND, WATER-REACTIVE, FLAMMABLE
, N.O.S.
Hazard Class: 4.3
UN Number: 3207
Packing group: II
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F
Risk Phrases:
R 11 Highly flammable.
R 15 Contact with water liberates extremely
flammable gases.
R 19 May form explosive peroxides.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 109-99-9: 1
CAS# 14044-65-6: No information available.
Canada
CAS# 109-99-9 is listed on Canadas DSL List.
CAS# 14044-65-6 is listed on Canadas NDSL List.
CAS# 109-99-9 is listed on Canadas Ingredient Disclosure List.
CAS# 14044-65-6 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 14044-65-6 is listed on the TSCA inventory.
