Name:
Bromoform spectro grade (inhibitor: ethanol) 99%
Synonym:
Tribromomethane; Methenyl tribromide
CAS:
75-25-2
Section 1 - Chemical Product
MSDS Name:Bromoform spectro grade (inhibitor: ethanol) 99%
Synonym:Tribromomethane; Methenyl tribromide
Synonym:Tribromomethane; Methenyl tribromide
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 75-25-2 | Bromoform | 99 | 200-854-6 |
| Hazard Symbols: T N Risk Phrases: 23 36/38 51/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation. Irritating to eyes and skin. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
Causes eye irritation. Lachrymator (substance which increases the flow of tears). May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be absorbed through the skin in harmful amounts.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression. Human fatalities have been reported from acute poisoning.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause narcotic effects in high concentration. Can produce delayed pulmonary edema.
Chronic:
Repeated exposure may cause central nervous system damage. Effects may be delayed.
Toxic by inhalation. Irritating to eyes and skin. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
Causes eye irritation. Lachrymator (substance which increases the flow of tears). May cause chemical conjunctivitis.
Skin:
Causes skin irritation. May be absorbed through the skin in harmful amounts.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system depression. Human fatalities have been reported from acute poisoning.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause narcotic effects in high concentration. Can produce delayed pulmonary edema.
Chronic:
Repeated exposure may cause central nervous system damage. Effects may be delayed.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub eyes or keep eyes closed.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Use extinguishing media appropriate to the surrounding fire. Substance is noncombustible.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Do NOT get water inside containers. For large fires, use water spray, fog or regular foam. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Use extinguishing media appropriate to the surrounding fire. Substance is noncombustible.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. Do NOT get water inside containers. For large fires, use water spray, fog or regular foam. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from metals. Do not store in metal containers. Keep away from strong bases.
Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from metals. Do not store in metal containers. Keep away from strong bases.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear to yellow
Odor: chloroform-like
pH: Not available.
Vapor Pressure: 4.4 mm Hg @20 C
Viscosity: Not available.
Boiling Point: 302 deg F
Freezing/Melting Point: 7.3-8.8 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: 0.1%
Specific Gravity/Density: 2.89
Molecular Formula: CHBr3
Molecular Weight: 252.73
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, metals, excess heat, strong oxidants, bases.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, metals, excess heat, strong oxidants, bases.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 75-25-2: PB5600000 LD50/LC50:
CAS# 75-25-2: Inhalation, mouse: LC50 = 12100 mg/m3/2H; Oral, mouse: LD50 = 1072 mg/kg; Oral, rat: LD50 = 933 mg/kg.
Carcinogenicity:
Bromoform - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 4/1/91 Other:
See actual entry in RTECS for complete information.
CAS# 75-25-2: PB5600000 LD50/LC50:
CAS# 75-25-2: Inhalation, mouse: LC50 = 12100 mg/m3/2H; Oral, mouse: LD50 = 1072 mg/kg; Oral, rat: LD50 = 933 mg/kg.
Carcinogenicity:
Bromoform - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 4/1/91 Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: BROMOFORM
Hazard Class: 6.1
UN Number: 2515
Packing Group: III
IMO
Shipping Name: BROMOFORM
Hazard Class: 6.1
UN Number: 2515
Packing Group: III
RID/ADR
Shipping Name: BROMOFORM
Hazard Class: 6.1
UN Number: 2515
Packing group: III
USA RQ:CAS# 75-25-2: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 23 Toxic by inhalation.
R 36/38 Irritating to eyes and skin.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 75-25-2: No information available.
United Kingdom Occupational Exposure Limits
CAS# 75-25-2: OES-United Kingdom, TWA 0.5 ppm TWA; 5.3 mg/m3 TWA
United Kingdom Maximum Exposure Limits
Canada
CAS# 75-25-2 is listed on Canadas DSL List.
CAS# 75-25-2 is listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 75-25-2: OEL-AUSTRALIA:TWA 0.5 ppm (5 mg/m3);Skin
OEL-BELGIUM:TWA 0.5 ppm (5.2 mg/m3);Skin
OEL-DENMARK:TWA 0.5 ppm (5 mg/m3);Skin
OEL-FINLAND:TWA 0.5 ppm (5 mg/m3);STEL 1.5 ppm (1 mg/m3);Skin
OEL-FRANCE:TWA 0.5 ppm (5 mg/m3);Skin
OEL-THE NETHERLANDS:TWA 0.5 ppm (5 mg/m3);Skin
OEL-THE PHILIPPINES:TWA 0.5 ppm (5 mg/m3);Skin
OEL-RUSSIA:STEL 5 mg/m3
OEL-SWITZERLAND:TWA 0.5 ppm (5 mg/m3);Skin
OEL-UNITED KINGDOM:TWA 0.5 ppm (5 mg/m3);Skin
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 75-25-2 is listed on the TSCA inventory.
