Name:
Cis-1 2-Dihydro-3-Methylcatechol 20w/v % Soln. in Ethyl Acetate
Synonym:
Cis-1,2-Dihydroxy-3-Methylcyclohexa-3,5-Diene
CAS:
141-78-6
Section 1 - Chemical Product
MSDS Name:Cis-1 2-Dihydro-3-Methylcatechol 20w/v % Soln. in Ethyl Acetate
Synonym:Cis-1,2-Dihydroxy-3-Methylcyclohexa-3,5-Diene
Synonym:Cis-1,2-Dihydroxy-3-Methylcyclohexa-3,5-Diene
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 141-78-6 | Ethyl acetate | 80 | 205-500-4 |
| Hazard Symbols: F Risk Phrases: 11 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable.
Potential Health Effects
Eye:
Causes eye irritation. Vapors may cause eye irritation.
Skin:
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
May cause irritation of the digestive tract. May cause liver and kidney damage. Ingestion of large amounts may cause central nervous depression. May cause headache, nausea, fatigue, and dizziness.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Inhalation of high concentrations may cause narcotic effects.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation. Chronic exposure may produce anemia, leukocytosis, cloudy swelling, and fatty degeneration of the viscera.
Highly flammable.
Potential Health Effects
Eye:
Causes eye irritation. Vapors may cause eye irritation.
Skin:
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
May cause irritation of the digestive tract. May cause liver and kidney damage. Ingestion of large amounts may cause central nervous depression. May cause headache, nausea, fatigue, and dizziness.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Inhalation of high concentrations may cause narcotic effects.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation. Chronic exposure may produce anemia, leukocytosis, cloudy swelling, and fatty degeneration of the viscera.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint.
Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. DO NOT USE DRY CHEMICAL for fires involving nitromethane or nitroethanes.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint.
Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. DO NOT USE DRY CHEMICAL for fires involving nitromethane or nitroethanes.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)
Wash thoroughly after handling. Use with adequate ventilation.
Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 141-78-6: United Kingdom, WEL - TWA: 200 ppm TWA United Kingdom, WEL - STEL: 400 ppm STEL United States OSHA: 400 ppm TWA; 1400 mg/m3 TWA Belgium - TWA: 400 ppm VLE; 1461 mg/m3 VLE France - VME: 400 ppm VME; 1400 mg/m3 VME Germany: 400 ppm TWA; 1500 mg/m3 TWA Japan: 200 ppm OEL; 720 mg/m3 OEL Malaysia: 400 ppm TWA; 1440 mg/m3 TWA Netherlands: 300 ppm STEL; 1100 mg/m3 STEL Netherlands: 150 ppm MAC; 550 mg/m3 MAC Russia: 200 mg/m3 TWA Spain: 400 ppm VLA-ED; 1460 mg/m3 VLA-ED CAS# 25506-13-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 141-78-6: United Kingdom, WEL - TWA: 200 ppm TWA United Kingdom, WEL - STEL: 400 ppm STEL United States OSHA: 400 ppm TWA; 1400 mg/m3 TWA Belgium - TWA: 400 ppm VLE; 1461 mg/m3 VLE France - VME: 400 ppm VME; 1400 mg/m3 VME Germany: 400 ppm TWA; 1500 mg/m3 TWA Japan: 200 ppm OEL; 720 mg/m3 OEL Malaysia: 400 ppm TWA; 1440 mg/m3 TWA Netherlands: 300 ppm STEL; 1100 mg/m3 STEL Netherlands: 150 ppm MAC; 550 mg/m3 MAC Russia: 200 mg/m3 TWA Spain: 400 ppm VLA-ED; 1460 mg/m3 VLA-ED CAS# 25506-13-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear brown
Odor: acetic odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: -4 deg C ( 24.80 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: .9460g/cm3
Molecular Formula: C7H10O2
Molecular Weight: 126.16
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
High temperatures, incompatible materials, ignition sources, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Chlorosulfonic acid, lithium aluminum hydride + 2-chloromethylfuran, lithium tetrahydroaluminate, oleum, potassium t-butoxide. Substance coming in contact with nitrates or strong acids/oxidizers/alkalies may cause fire.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
High temperatures, incompatible materials, ignition sources, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Chlorosulfonic acid, lithium aluminum hydride + 2-chloromethylfuran, lithium tetrahydroaluminate, oleum, potassium t-butoxide. Substance coming in contact with nitrates or strong acids/oxidizers/alkalies may cause fire.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 141-78-6: AH5425000 CAS# 25506-13-2 unlisted.
LD50/LC50:
CAS# 141-78-6: Inhalation, mouse: LC50 = 45 gm/m3/2H; Inhalation, rat: LC50 = 200 gm/m3; Oral, mouse: LD50 = 4100 mg/kg; Oral, rabbit: LD50 = 4935 mg/kg; Oral, rat: LD50 = 5620 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 25506-13-2.
Carcinogenicity:
Ethyl acetate - Not listed by ACGIH, IARC, or NTP.
Cis-1,2-Dihydro-3-Methylcatechol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 141-78-6: AH5425000 CAS# 25506-13-2 unlisted.
LD50/LC50:
CAS# 141-78-6: Inhalation, mouse: LC50 = 45 gm/m3/2H; Inhalation, rat: LC50 = 200 gm/m3; Oral, mouse: LD50 = 4100 mg/kg; Oral, rabbit: LD50 = 4935 mg/kg; Oral, rat: LD50 = 5620 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 25506-13-2.
Carcinogenicity:
Ethyl acetate - Not listed by ACGIH, IARC, or NTP.
Cis-1,2-Dihydro-3-Methylcatechol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: 230mg/L; 96HDaphnid LC50=2500 mg/L/96H Golden orfe LC50=270 mg/L/48H Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."
Fish: Fathead Minnow: 230mg/L; 96HDaphnid LC50=2500 mg/L/96H Golden orfe LC50=270 mg/L/48H Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FLAMMABLE LIQUID, N.O.S.*
Hazard Class: 3
UN Number: 1993
Packing Group: II
IMO
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3.2
UN Number: 1993
Packing Group: II
RID/ADR
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3
UN Number: 1993
Packing group: II
USA RQ: CAS# 141-78-6: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F
Risk Phrases:
R 11 Highly flammable.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 23 Do not inhale gas/fumes/vapour/spray.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 141-78-6: 1
CAS# 25506-13-2: No information available.
Canada
CAS# 141-78-6 is listed on Canadas DSL List.
CAS# 141-78-6 is listed on Canadas Ingredient Disclosure List.
CAS# 25506-13-2 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 141-78-6 is listed on the TSCA inventory.
CAS# 25506-13-2 is not listed on the TSCA inventory.
It is for research and development use only.
