Name:
Custom Made Multi-Element Standard
Synonym:
None
CAS:
1327-53-3
Section 1 - Chemical Product
MSDS Name:Custom Made Multi-Element Standard
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 1327-53-3 | Arsenic Trioxide | <1.0 | 215-481-4 |
| Hazard Symbols: T Risk Phrases: 20/21/22 49 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. May cause cancer by inhalation.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Repeated or prolonged skin contact may cause antimony measles characterized by itchy papules and pustules around the sweat and fat glands. Exposure to arsenic compounds may produce hyperpigmentation of the skin and hyperkeratoses of plantar and palmar surfaces as well as both primary irritation and sensitization types.
Ingestion:
Ingestion of arsenical compounds may cause burning of the lips, throat constriction, swallowing difficulties, severe abdominal pain, severe nausea, projectile vomiting, and profuse diarrhea. Ingestion of lead compounds can cause toxic effects in the blood-forming organs, kidneys and central nervous system. Ingestion of arsenic compounds can produce convulsions, coma, and possibly death within 24 hours. Ingestion of copper compounds may produce systemic toxic effects to the kidney and liver and central nervous excitation followed by depression.
Inhalation:
Inhalation of arsenic compounds may lead to irritation of the respiratory tract and to possible nasal perforation. Long-term exposure to arsenic compounds may produce impairment of peripheral circulation. Antimony compounds may enter the body through the lungs.
Chronic:
Chronic exposure to water insoluble hexavalent chromium compounds has been shown to be associated with lung cancer and gastrointestinal tract tumors. Chronic exposure to lead may result in plumbism which is characterized by lead line in gum, headache, muscle weakness, mental changes. Individuals with Wilsons disease are unable to metabolize copper. Thus, copper accumulates in various tissues and may result in liver, kidney, and brain damage. Cobalt compounds may cause cancer based upon animal studies. Arsenic trioxide can cause cancer in humans. Other long term effects include: anemia, liver and kidney damage. Cadmium and compounds may cause lung, liver and kidney damage and lung and prostate cancer in humans. Chronic exposure to arsenical dust may cause shortness of breath, nausea, chest pains, and garlic odor. Chronic copper poisoning in man is recognized in the form of Wilsons disease.
Symptoms of overexposure to nickel can cause sensitization, dermatitis, allergic asthma and pneumonitis. Inorganic arsenic compounds may cause skin and lung cancers in humans. Chronic expsoure to lead may cause adverse effects on human reproduction, embryonic and fetal development and postnatal (e.g., mental) development.
Harmful by inhalation, in contact with skin and if swallowed. May cause cancer by inhalation.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Repeated or prolonged skin contact may cause antimony measles characterized by itchy papules and pustules around the sweat and fat glands. Exposure to arsenic compounds may produce hyperpigmentation of the skin and hyperkeratoses of plantar and palmar surfaces as well as both primary irritation and sensitization types.
Ingestion:
Ingestion of arsenical compounds may cause burning of the lips, throat constriction, swallowing difficulties, severe abdominal pain, severe nausea, projectile vomiting, and profuse diarrhea. Ingestion of lead compounds can cause toxic effects in the blood-forming organs, kidneys and central nervous system. Ingestion of arsenic compounds can produce convulsions, coma, and possibly death within 24 hours. Ingestion of copper compounds may produce systemic toxic effects to the kidney and liver and central nervous excitation followed by depression.
Inhalation:
Inhalation of arsenic compounds may lead to irritation of the respiratory tract and to possible nasal perforation. Long-term exposure to arsenic compounds may produce impairment of peripheral circulation. Antimony compounds may enter the body through the lungs.
Chronic:
Chronic exposure to water insoluble hexavalent chromium compounds has been shown to be associated with lung cancer and gastrointestinal tract tumors. Chronic exposure to lead may result in plumbism which is characterized by lead line in gum, headache, muscle weakness, mental changes. Individuals with Wilsons disease are unable to metabolize copper. Thus, copper accumulates in various tissues and may result in liver, kidney, and brain damage. Cobalt compounds may cause cancer based upon animal studies. Arsenic trioxide can cause cancer in humans. Other long term effects include: anemia, liver and kidney damage. Cadmium and compounds may cause lung, liver and kidney damage and lung and prostate cancer in humans. Chronic exposure to arsenical dust may cause shortness of breath, nausea, chest pains, and garlic odor. Chronic copper poisoning in man is recognized in the form of Wilsons disease.
Symptoms of overexposure to nickel can cause sensitization, dermatitis, allergic asthma and pneumonitis. Inorganic arsenic compounds may cause skin and lung cancers in humans. Chronic expsoure to lead may cause adverse effects on human reproduction, embryonic and fetal development and postnatal (e.g., mental) development.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Blood cadmium levels are not indicative of exposure. Individuals with Wilsons disease are more susceptible to chronic copper poisoning.
Antidote: The use of a metal chelator should be determined only by qualified medical personnel.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Blood cadmium levels are not indicative of exposure. Individuals with Wilsons disease are more susceptible to chronic copper poisoning.
Antidote: The use of a metal chelator should be determined only by qualified medical personnel.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Non-combustible, substance itself does not burn but may decompose upon heating to produce irritating, corrosive and/or toxic fumes.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1327-53-3: United Kingdom, WEL - TWA: (listed as arsenic compounds, n.o.s.): mg/m3 TWA (except arsine, as As) United Kingdom, WEL - STEL: (listed as arsenic compounds, n.o.s.) 0.3 mg/m3 STEL (except arsine, as As) United States OSHA: 0.5 mg/m3 TWA (listed under Arsenic).5 ??g/m3 Action Level (as As); 10 ??g/m3 PEL (as As. Cancer hazard - see 2 CFR 1 910.1018. Arsine excepted) (listed under Arsenic, inorgani compounds).
Belgium - TWA: (listed as arsenic, inorganic compounds): 0.01 mg/ VLE (as As) France - VME: 0.2 mg/m3 VME (as As) Germany: 0.1 mg/m3 TWA (inhalable fraction) Japan: (listed as arsenic compounds, n.o.s.): 3 ??g/m3 OEL (refere value, as As) Malaysia: (listed as arsenic, inorganic compounds): 0.01 mg/m3 TW (as As, except arsine) Netherlands: (listed as arsenic, inorganic compounds): 0.1 mg/m3 (as As) Netherlands: (listed as arsenic, inorganic compounds): 0.050 mg/m MAC (as As) Russia: (listed as arsenic, inorganic compounds): 0.04 mg/m3 TWA As) Russia: (listed as arsenic, inorganic compounds): 0.01 mg/m3 STEL As) Spain: 0.1 mg/m3 VLA-ED (as As) CAS# 7439-92-1: United Kingdom, WEL - TWA: 0.15 mg/m3 TWA United Kingdom, WEL - STEL: 0.45 mg/m3 TWA United States OSHA: ; 50 ??g/m3 PEL (as Pb); 30 ??g/m3 Action Level Pb. Poison - see 29 CFR 1910.10 25) Belgium - TWA: (listed as lead, inorganic compounds): 0.15 mg/m3 (dust and fume) France - VME: 0.1 mg/m3 VME Germany: 0.1 mg/m3 TWA (inhalable fraction) Japan: 0.1 mg/m3 OEL Malaysia: 0.05 mg/m3 TWA Netherlands: 0.15 mg/m3 MAC Russia: 0.01 mg/m3 TWA Russia: 0.005 mg/m3 STEL Spain: 0.15 mg/m3 VLA-ED CAS# 7440-02-0: United Kingdom, WEL - TWA: 0.5 mg/m3 TWA United Kingdom, WEL - STEL: 1.5 mg/m3 STEL United States OSHA: 1 mg/m3 TWA Belgium - TWA: 1 mg/m3 VLE France - VME: 1 mg/m3 VME; 1 mg/m3 VME (metal gratings) Germany: 0.5 mg/m3 TWA (inhalable fraction) Japan: 1 mg/m3 OEL Malaysia: 1.5 mg/m3 TWA (inhalable fraction) Netherlands: 1 mg/m3 MAC Russia: 0.05 mg/m3 TWA Spain: 1 mg/m3 VLA-ED CAS# 7440-36-0: United Kingdom, WEL - TWA: 0.5 mg/m3 TWA United Kingdom, WEL - STEL: 1.5 mg/m3 STEL United States OSHA: 0.5 mg/m3 TWA Belgium - TWA: 0.5 mg/m3 VLE France - VME: 0.5 mg/m3 VME Germany: 0.5 mg/m3 TWA (inhalable fraction) Japan: 0.1 mg/m3 OEL Malaysia: 0.5 mg/m3 TWA Netherlands: 0.5 mg/m3 MAC Russia: 0.5 mg/m3 TWA Russia: 0.2 mg/m3 STEL Spain: 0.5 mg/m3 VLA-ED CAS# 7440-43-9: United Kingdom, WEL - TWA: 0.025 mg/m3 TWA United Kingdom, WEL - STEL: 0.075 mg/m3 STEL United States OSHA: 0.2 mg/m3 TWA (dust); 0.1 mg/m3 TWA (fume); 0 mg/m3 Ceiling (dust); 0.3 mg/m3 Ceiling (fume); 2.5 ??g/m3 Action Level; 5 ??g/m3 TWA (Do not eat, drink or chew tobacco or gum or apply cosmetics in regulated areas. Carcinogen - dust can cause l and kidn Belgium - TWA: 0.002 mg/m3 VLE (respirable particulates); 0.01 mg VLE (inhalable particulate France - VME: 0.05 mg/m3 VME Germany: 0.03 mg/m3 TWA (dusts/aerosols, inhalable fraction, batt production - thermal Japan: 0.05 mg/m3 OEL Malaysia: 0.01 mg/m3 TWA; 0.002 mg/m3 TWA (respirable fraction) Netherlands: (listed as chromium compounds): 0.01 mg/m3 STEL Netherlands: 0.005 mg/m3 MAC Russia: 0.05 mg/m3 TWA Russia: 0.01 mg/m3 STEL Spain: 0.01 mg/m3 VLA-ED (inhalable fraction); 0.002 mg/m3 VLA-ED (respirable fraction) CAS# 7440-47-3: United Kingdom, WEL - TWA: 0.5 mg/m3 TWA United Kingdom, WEL - STEL: 1.5 mg/m3 STEL United States OSHA: 1 mg/m3 TWA Belgium - TWA: 0.5 mg/m3 VLE France - VME: 0.5 mg/m3 VME Japan: 0.5 mg/m3 OEL Malaysia: 0.5 mg/m3 TWA Netherlands: (listed as chromium compounds): 0.01 mg/m3 STEL Netherlands: 0.5 mg/m3 MAC Spain: 0.5 mg/m3 VLA-ED CAS# 7440-48-4: United Kingdom, WEL - TWA: 0.1 mg/m3 TWA United Kingdom, WEL - STEL: 0.3 mg/m3 STEL United States OSHA: 0.1 mg/m3 TWA (dust and fume) Belgium - TWA: 0.02 mg/m3 VLE (dust and fume) Germany: 0.5 mg/m3 TWA (inhalable fraction, production of cobalt powder and catalysts, tu Japan: 0.05 mg/m3 OEL Malaysia: 0.02 mg/m3 TWA Netherlands: 0.02 mg/m3 MAC (dust and smoke, as Co) Russia: 0.5 mg/m3 TWA (dust and/or fumes) Spain: 0.02 mg/m3 VLA-ED CAS# 7440-50-8: United Kingdom, WEL - TWA: 0.2 mg/m3 TWA (fume); 1 mg/m3 TWA (dus and mist) United Kingdom, WEL - STEL: 0.6 mg/m3 STEL (fume); 2 mg/m3 STEL ( and mist) United States OSHA: 0.1 mg/m3 TWA (fume); 1 mg/m3 TWA (dusts and mists) Belgium - TWA: 0.2 mg/m3 VLE (fume); 1 mg/m3 VLE (dust and mist) France - VME: 0.2 mg/m3 VME (fume); 1 mg/m3 VME (dust, as Cu) France - VLE: 2 mg/m3 VLE (dust, as Cu) Germany: 1 mg/m3 TWA (inhalable fraction); 0.1 mg/m3 TWA (respira fraction, smoke) Malaysia: 0.2 mg/m3 TWA (fume, as Cu); 1 mg/m3 TWA (dust and mist Cu) Netherlands: 0.2 mg/m3 MAC (smoke); 1 mg/m3 MAC (dust) Russia: 1 mg/m3 TWA (dust) Russia: 0.5 mg/m3 STEL (dust) Spain: 0.2 mg/m3 VLA-ED (fume); 1 mg/m3 VLA-ED (dust and mist, as CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1327-53-3: United Kingdom, WEL - TWA: (listed as arsenic compounds, n.o.s.): mg/m3 TWA (except arsine, as As) United Kingdom, WEL - STEL: (listed as arsenic compounds, n.o.s.) 0.3 mg/m3 STEL (except arsine, as As) United States OSHA: 0.5 mg/m3 TWA (listed under Arsenic).5 ??g/m3 Action Level (as As); 10 ??g/m3 PEL (as As. Cancer hazard - see 2 CFR 1 910.1018. Arsine excepted) (listed under Arsenic, inorgani compounds).
Belgium - TWA: (listed as arsenic, inorganic compounds): 0.01 mg/ VLE (as As) France - VME: 0.2 mg/m3 VME (as As) Germany: 0.1 mg/m3 TWA (inhalable fraction) Japan: (listed as arsenic compounds, n.o.s.): 3 ??g/m3 OEL (refere value, as As) Malaysia: (listed as arsenic, inorganic compounds): 0.01 mg/m3 TW (as As, except arsine) Netherlands: (listed as arsenic, inorganic compounds): 0.1 mg/m3 (as As) Netherlands: (listed as arsenic, inorganic compounds): 0.050 mg/m MAC (as As) Russia: (listed as arsenic, inorganic compounds): 0.04 mg/m3 TWA As) Russia: (listed as arsenic, inorganic compounds): 0.01 mg/m3 STEL As) Spain: 0.1 mg/m3 VLA-ED (as As) CAS# 7439-92-1: United Kingdom, WEL - TWA: 0.15 mg/m3 TWA United Kingdom, WEL - STEL: 0.45 mg/m3 TWA United States OSHA: ; 50 ??g/m3 PEL (as Pb); 30 ??g/m3 Action Level Pb. Poison - see 29 CFR 1910.10 25) Belgium - TWA: (listed as lead, inorganic compounds): 0.15 mg/m3 (dust and fume) France - VME: 0.1 mg/m3 VME Germany: 0.1 mg/m3 TWA (inhalable fraction) Japan: 0.1 mg/m3 OEL Malaysia: 0.05 mg/m3 TWA Netherlands: 0.15 mg/m3 MAC Russia: 0.01 mg/m3 TWA Russia: 0.005 mg/m3 STEL Spain: 0.15 mg/m3 VLA-ED CAS# 7440-02-0: United Kingdom, WEL - TWA: 0.5 mg/m3 TWA United Kingdom, WEL - STEL: 1.5 mg/m3 STEL United States OSHA: 1 mg/m3 TWA Belgium - TWA: 1 mg/m3 VLE France - VME: 1 mg/m3 VME; 1 mg/m3 VME (metal gratings) Germany: 0.5 mg/m3 TWA (inhalable fraction) Japan: 1 mg/m3 OEL Malaysia: 1.5 mg/m3 TWA (inhalable fraction) Netherlands: 1 mg/m3 MAC Russia: 0.05 mg/m3 TWA Spain: 1 mg/m3 VLA-ED CAS# 7440-36-0: United Kingdom, WEL - TWA: 0.5 mg/m3 TWA United Kingdom, WEL - STEL: 1.5 mg/m3 STEL United States OSHA: 0.5 mg/m3 TWA Belgium - TWA: 0.5 mg/m3 VLE France - VME: 0.5 mg/m3 VME Germany: 0.5 mg/m3 TWA (inhalable fraction) Japan: 0.1 mg/m3 OEL Malaysia: 0.5 mg/m3 TWA Netherlands: 0.5 mg/m3 MAC Russia: 0.5 mg/m3 TWA Russia: 0.2 mg/m3 STEL Spain: 0.5 mg/m3 VLA-ED CAS# 7440-43-9: United Kingdom, WEL - TWA: 0.025 mg/m3 TWA United Kingdom, WEL - STEL: 0.075 mg/m3 STEL United States OSHA: 0.2 mg/m3 TWA (dust); 0.1 mg/m3 TWA (fume); 0 mg/m3 Ceiling (dust); 0.3 mg/m3 Ceiling (fume); 2.5 ??g/m3 Action Level; 5 ??g/m3 TWA (Do not eat, drink or chew tobacco or gum or apply cosmetics in regulated areas. Carcinogen - dust can cause l and kidn Belgium - TWA: 0.002 mg/m3 VLE (respirable particulates); 0.01 mg VLE (inhalable particulate France - VME: 0.05 mg/m3 VME Germany: 0.03 mg/m3 TWA (dusts/aerosols, inhalable fraction, batt production - thermal Japan: 0.05 mg/m3 OEL Malaysia: 0.01 mg/m3 TWA; 0.002 mg/m3 TWA (respirable fraction) Netherlands: (listed as chromium compounds): 0.01 mg/m3 STEL Netherlands: 0.005 mg/m3 MAC Russia: 0.05 mg/m3 TWA Russia: 0.01 mg/m3 STEL Spain: 0.01 mg/m3 VLA-ED (inhalable fraction); 0.002 mg/m3 VLA-ED (respirable fraction) CAS# 7440-47-3: United Kingdom, WEL - TWA: 0.5 mg/m3 TWA United Kingdom, WEL - STEL: 1.5 mg/m3 STEL United States OSHA: 1 mg/m3 TWA Belgium - TWA: 0.5 mg/m3 VLE France - VME: 0.5 mg/m3 VME Japan: 0.5 mg/m3 OEL Malaysia: 0.5 mg/m3 TWA Netherlands: (listed as chromium compounds): 0.01 mg/m3 STEL Netherlands: 0.5 mg/m3 MAC Spain: 0.5 mg/m3 VLA-ED CAS# 7440-48-4: United Kingdom, WEL - TWA: 0.1 mg/m3 TWA United Kingdom, WEL - STEL: 0.3 mg/m3 STEL United States OSHA: 0.1 mg/m3 TWA (dust and fume) Belgium - TWA: 0.02 mg/m3 VLE (dust and fume) Germany: 0.5 mg/m3 TWA (inhalable fraction, production of cobalt powder and catalysts, tu Japan: 0.05 mg/m3 OEL Malaysia: 0.02 mg/m3 TWA Netherlands: 0.02 mg/m3 MAC (dust and smoke, as Co) Russia: 0.5 mg/m3 TWA (dust and/or fumes) Spain: 0.02 mg/m3 VLA-ED CAS# 7440-50-8: United Kingdom, WEL - TWA: 0.2 mg/m3 TWA (fume); 1 mg/m3 TWA (dus and mist) United Kingdom, WEL - STEL: 0.6 mg/m3 STEL (fume); 2 mg/m3 STEL ( and mist) United States OSHA: 0.1 mg/m3 TWA (fume); 1 mg/m3 TWA (dusts and mists) Belgium - TWA: 0.2 mg/m3 VLE (fume); 1 mg/m3 VLE (dust and mist) France - VME: 0.2 mg/m3 VME (fume); 1 mg/m3 VME (dust, as Cu) France - VLE: 2 mg/m3 VLE (dust, as Cu) Germany: 1 mg/m3 TWA (inhalable fraction); 0.1 mg/m3 TWA (respira fraction, smoke) Malaysia: 0.2 mg/m3 TWA (fume, as Cu); 1 mg/m3 TWA (dust and mist Cu) Netherlands: 0.2 mg/m3 MAC (smoke); 1 mg/m3 MAC (dust) Russia: 1 mg/m3 TWA (dust) Russia: 0.5 mg/m3 STEL (dust) Spain: 0.2 mg/m3 VLA-ED (fume); 1 mg/m3 VLA-ED (dust and mist, as CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: almost colorless
Odor: practically odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: > 100 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Slightly soluble.
Specific Gravity/Density: >1.000
Molecular Formula: Solution
Molecular Weight: 0
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, acids, excess heat, bases.
Incompatibilities with Other Materials:
Strong acids, strong bases, water reactive substances (e.g. acetic anyhdride, alkyl aluminum chloride, calcium carbide, ethyl dichlorosilane).
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, antimony/antimony oxides, nickel oxide, lead/lead oxides, cadmium fumes, copper fumes, arsenic fumes, chromium fumes, cobalt/cobalt oxides.
Hazardous Polymerization: Will not occur.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, acids, excess heat, bases.
Incompatibilities with Other Materials:
Strong acids, strong bases, water reactive substances (e.g. acetic anyhdride, alkyl aluminum chloride, calcium carbide, ethyl dichlorosilane).
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, antimony/antimony oxides, nickel oxide, lead/lead oxides, cadmium fumes, copper fumes, arsenic fumes, chromium fumes, cobalt/cobalt oxides.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1327-53-3: CG3325000 CAS# 7439-92-1: OF7525000 CAS# 7440-02-0: QR5950000 QR6126100 QR6555000 QR7120000 CAS# 7440-36-0: CC4025000 CAS# 7440-43-9: EU9800000 CAS# 7440-47-3: GB4200000 CAS# 7440-48-4: GF8750000 GF8850000 GG0375000 CAS# 7440-50-8: GL5325000 GL7440000 GL7590000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 1327-53-3: Oral, mouse: LD50 = 20 mg/kg; Oral, rabbit: LD50 = 20190 ug/kg; Oral, rat: LD50 = 10 mg/kg.
CAS# 7439-92-1.
CAS# 7440-02-0.
CAS# 7440-36-0: Oral, rat: LD50 = 7 gm/kg.
CAS# 7440-43-9: Inhalation, rat: LC50 = 25 mg/m3/30M; Oral, mouse: LD50 = 890 mg/kg; Oral, rat: LD50 = 2330 mg/kg.
CAS# 7440-47-3.
CAS# 7440-48-4: Oral, rat: LD50 = 6171 mg/kg.
CAS# 7440-50-8.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Arsenic Trioxide - California: carcinogen, initial date 2/27/87 (listed as Arsenic, inorg NTP: Known carcinogen (listed as Arsenic, inorganic compounds).
IARC: Group 1 carcinogen (listed as Arsenic).
Lead - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 10/1/92 NTP: Suspect carcinogen IARC: Group 2B carcinogen Nickel - California: carcinogen, initial date 10/1/89 NTP: Suspect carcinogen IARC: Group 1 carcinogen (listed as Nickel compounds).
Antimony - Not listed by ACGIH, IARC, or NTP.
Cadmium - ACGIH: A2 - Suspected Human Carcinogen (listed as Cadmium compoun California: carcinogen, initial date 10/1/87 NTP: Known carcinogen IARC: Group 1 carcinogen Chromium - Not listed by ACGIH, IARC, or NTP.
Cobalt - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 7/1/92 (powder) IARC: Group 2B carcinogen Copper - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 1327-53-3: CG3325000 CAS# 7439-92-1: OF7525000 CAS# 7440-02-0: QR5950000 QR6126100 QR6555000 QR7120000 CAS# 7440-36-0: CC4025000 CAS# 7440-43-9: EU9800000 CAS# 7440-47-3: GB4200000 CAS# 7440-48-4: GF8750000 GF8850000 GG0375000 CAS# 7440-50-8: GL5325000 GL7440000 GL7590000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 1327-53-3: Oral, mouse: LD50 = 20 mg/kg; Oral, rabbit: LD50 = 20190 ug/kg; Oral, rat: LD50 = 10 mg/kg.
CAS# 7439-92-1.
CAS# 7440-02-0.
CAS# 7440-36-0: Oral, rat: LD50 = 7 gm/kg.
CAS# 7440-43-9: Inhalation, rat: LC50 = 25 mg/m3/30M; Oral, mouse: LD50 = 890 mg/kg; Oral, rat: LD50 = 2330 mg/kg.
CAS# 7440-47-3.
CAS# 7440-48-4: Oral, rat: LD50 = 6171 mg/kg.
CAS# 7440-50-8.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Arsenic Trioxide - California: carcinogen, initial date 2/27/87 (listed as Arsenic, inorg NTP: Known carcinogen (listed as Arsenic, inorganic compounds).
IARC: Group 1 carcinogen (listed as Arsenic).
Lead - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 10/1/92 NTP: Suspect carcinogen IARC: Group 2B carcinogen Nickel - California: carcinogen, initial date 10/1/89 NTP: Suspect carcinogen IARC: Group 1 carcinogen (listed as Nickel compounds).
Antimony - Not listed by ACGIH, IARC, or NTP.
Cadmium - ACGIH: A2 - Suspected Human Carcinogen (listed as Cadmium compoun California: carcinogen, initial date 10/1/87 NTP: Known carcinogen IARC: Group 1 carcinogen Chromium - Not listed by ACGIH, IARC, or NTP.
Cobalt - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 7/1/92 (powder) IARC: Group 2B carcinogen Copper - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOXIC LIQUID, INORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 3287
Packing Group: III
IMO
Shipping Name: TOXIC LIQUID, INORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 3287
Packing Group: III
RID/ADR
Shipping Name: TOXIC LIQUID, INORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 3287
Packing group: III
USA RQ: CAS# 1327-53-3: 1 lb final RQ; 0.454 kg final RQ
USA RQ: CAS# 7439-92-1: 10 lb final RQ (no reporting of releases of this hazardo
USA RQ: CAS# 7440-02-0: 100 lb final RQ (no reporting of releases of this hazard
USA RQ: CAS# 7440-36-0: 5000 lb final RQ (no reporting of releases of this hazar
USA RQ: CAS# 7440-43-9: 10 lb final RQ (no reporting of releases of this hazardo
USA RQ: CAS# 7440-47-3: 5000 lb final RQ (no reporting of releases of this hazar
USA RQ: CAS# 7440-50-8: 5000 lb final RQ (no reporting of releases of this hazar
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 49 May cause cancer by inhalation.
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1327-53-3: 3
CAS# 7439-92-1: No information available.
CAS# 7440-02-0: No information available.
CAS# 7440-36-0: No information available.
CAS# 7440-43-9: No information available.
CAS# 7440-47-3: No information available.
CAS# 7440-48-4: 1
CAS# 7440-50-8: 0
CAS# 7732-18-5: No information available.
Canada
CAS# 1327-53-3 is listed on Canadas DSL List.
CAS# 7439-92-1 is listed on Canadas DSL List.
CAS# 7440-02-0 is listed on Canadas DSL List.
CAS# 7440-36-0 is listed on Canadas DSL List.
CAS# 7440-43-9 is listed on Canadas DSL List.
CAS# 7440-47-3 is listed on Canadas DSL List.
CAS# 7440-48-4 is listed on Canadas DSL List.
CAS# 7440-50-8 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 1327-53-3 is listed on Canadas Ingredient Disclosure List.
CAS# 7439-92-1 is listed on Canadas Ingredient Disclosure List.
CAS# 7440-02-0 is listed on Canadas Ingredient Disclosure List.
CAS# 7440-36-0 is listed on Canadas Ingredient Disclosure List.
CAS# 7440-43-9 is listed on Canadas Ingredient Disclosure List.
CAS# 7440-47-3 is listed on Canadas Ingredient Disclosure List.
CAS# 7440-48-4 is listed on Canadas Ingredient Disclosure List.
CAS# 7440-50-8 is listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1327-53-3 is listed on the TSCA inventory.
CAS# 7439-92-1 is listed on the TSCA inventory.
CAS# 7440-02-0 is listed on the TSCA inventory.
CAS# 7440-36-0 is listed on the TSCA inventory.
CAS# 7440-43-9 is listed on the TSCA inventory.
CAS# 7440-47-3 is listed on the TSCA inventory.
CAS# 7440-48-4 is listed on the TSCA inventory.
CAS# 7440-50-8 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
