Name:
Cyanocobalamin
Synonym:
Anacobin; Vitamin B12; 1H-Benzimidazole, 5,6-dimethyl-1-(3-O-phosphono-alpha-d-ribofuranosyl)-, monoester with cobinamide cyanide hydroxide, inner salt; Cyanocobalamin
CAS:
68-19-9
Section 1 - Chemical Product
MSDS Name:Cyanocobalamin
Synonym:Anacobin; Vitamin B12; 1H-Benzimidazole, 5,6-dimethyl-1-(3-O-phosphono-alpha-d-ribofuranosyl)-, monoester with cobinamide cyanide hydroxide, inner salt; Cyanocobalamin
Synonym:Anacobin; Vitamin B12; 1H-Benzimidazole, 5,6-dimethyl-1-(3-O-phosphono-alpha-d-ribofuranosyl)-, monoester with cobinamide cyanide hydroxide, inner salt; Cyanocobalamin
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 68-19-9 | Cyanocobalamin | >96 | 200-680-0 |
| Hazard Symbols: None Listed. Risk Phrases: None Listed. |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Light sensitive.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Contact may cause transient eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause convulsions, tremors, muscular contractions or spasticity, diarrhea, or fever.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Not available.
Light sensitive.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Contact may cause transient eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause convulsions, tremors, muscular contractions or spasticity, diarrhea, or fever.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid breathing dust.
Storage:
Store protected from moisture. Store protected from light.
Refrigeration has been recommended.
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid breathing dust.
Storage:
Store protected from moisture. Store protected from light.
Refrigeration has been recommended.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 68-19-9: United Kingdom, WEL - TWA: (listed as cobalt compounds): 0.1 mg/m TWA (as Co) United Kingdom, WEL - STEL: (listed as cobalt compounds): 0.3 mg/ STEL (as Co) Japan: (listed as cobalt compounds): 0.05 mg/m3 OEL (as Co) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 68-19-9: United Kingdom, WEL - TWA: (listed as cobalt compounds): 0.1 mg/m TWA (as Co) United Kingdom, WEL - STEL: (listed as cobalt compounds): 0.3 mg/ STEL (as Co) Japan: (listed as cobalt compounds): 0.05 mg/m3 OEL (as Co) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystalline powder
Color: dark red
Odor: odorless
pH: aq solns are neutral
Vapor Pressure: Negligible.
Viscosity: Not available.
Boiling Point: > 300 deg C
Freezing/Melting Point: > 300 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Moderately soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: C63H88CoN14O14P
Molecular Weight: 1355.38
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. May decompose when exposed to light. Darkens at 210 - 220C.
Conditions to Avoid:
Light, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizers, strong acids.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of phosphorus, carbon dioxide, oxides of cobalt.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures. May decompose when exposed to light. Darkens at 210 - 220C.
Conditions to Avoid:
Light, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizers, strong acids.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, oxides of phosphorus, carbon dioxide, oxides of cobalt.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 68-19-9: GG3750000 LD50/LC50:
Not available.
Carcinogenicity:
Cyanocobalamin - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 68-19-9: GG3750000 LD50/LC50:
Not available.
Carcinogenicity:
Cyanocobalamin - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 68-19-9: No information available.
Canada
CAS# 68-19-9 is listed on Canadas DSL List.
CAS# 68-19-9 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 68-19-9 is listed on the TSCA inventory.
