MSDS Name:Cyclohexylmagnesium chloride 1.3M solution in THF/toluene
Synonym:None Known

EMERGENCY OVERVIEW
Highly flammable. Reacts violently with water liberating extremely flammable gases. May form explosive peroxides. Causes burns. Harmful by inhalation. Possible risk of harm to the unborn child. Vapours may cause drowsiness and dizziness.Moisture sensitive.Light sensitive.Water-reactive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns. May be absorbed through the skin.
Ingestion:
Causes gastrointestinal tract burns. May cause central nervous system depression. May be harmful if swallowed.
Inhalation:
Harmful if inhaled. Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes chemical burns to the respiratory tract. Inhalation may cause coughing, difficulty breathing and loss of consciousness. Inhalation of vapors may cause drowsiness and dizziness. Inhalation of high concentrations (>200 ppm) of toluene are clearly associated with CNS encephalopathy, headache, depression, lassitude (weakness, exhaustion), impaired coordination, transient memory loss, and impaired reaction time.
Chronic:
Prolonged or repeated eye contact may cause conjunctivitis.
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause liver and kidney damage. May cause lung damage.
Narcotic in high concentrations. Chronic exposure may cause effects similar to those of acute exposure. in cases of occupational toluene exposure, there has been at least one report of renal toxicity following a 40-year occupational toluene exposure.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. If water-reactive products are embedded in the skin, no water should be applied. The embedded products should be covered with a light oil.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively. Persons with skin problems or liver, kidney, lung, or blood diseases may be at increased risk from exposure to this substance.

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Water Reactive. Material will react with water and may release a flammable and/or toxic gas. Extremely flammable liquid and vapor. May form explosive peroxides. Vapors are heavier than air and may travel to a source of ignition and flash back.
Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide. Do NOT use carbon dioxide. DO NOT USE WATER OR FOAM. Smother with dry sand, dry clay, dry ground limestone (CaCO3), or use approved Class D extinguishers.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. Do not expose spill to water.

Handling:
Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Do not ingest or inhale.
Do not allow contact with water. Use only in a chemical fume hood.
Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep away from heat, sparks and flame.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Flammables-area. Corrosives area. Water free area. Store under nitrogen. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.

Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 108-88-3: United Kingdom, WEL - TWA: 50 ppm TWA; 191 mg/m3 TWA United Kingdom, WEL - STEL: 150 ppm STEL; 574 mg/m3 STEL United States OSHA: 200 ppm TWA; 300 ppm Ceiling Belgium - TWA: 50 ppm VLE; 191 mg/m3 VLE France - VME: 100 ppm VME; 375 mg/m3 VME France - VLE: 150 ppm VLE; 550 mg/m3 VLE Germany: 50 ppm TWA; 190 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 188 mg/m3 OEL Malaysia: 50 ppm TWA; 188 mg/m3 TWA Netherlands: 40 ppm MAC; 150 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 191 mg/m3 VLA-ED CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 931-51-1: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Physical State: Liquid
Color: dark brown
Odor: solvent odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: vigorous reaction
Specific Gravity/Density: 0.950
Molecular Formula: C6H11ClMg
Molecular Weight: 142.91

Chemical Stability:
Reacts violently with water. Moisture sensitive. Light sensitive.
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation. THF should never be distilled to dryness.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, exposure to moist air or water, evaporating to near dryness, confined spaces, direct sunlight..
Incompatibilities with Other Materials:
Water, acids, alcohols, oxidizing agents.
Hazardous Decomposition Products:
Chlorine, carbon monoxide, carbon dioxide, ammonia and hydrochloric acid fumes, hydrogen fluoride gas, hydrogen bromide, benzene, oxides of magnesium, bromine, fluorine, organic fluorides.
Hazardous Polymerization: Has not been reported

RTECS#:
CAS# 108-88-3: XS5250000 CAS# 109-99-9: LU5950000 CAS# 931-51-1 unlisted.
LD50/LC50:
CAS# 108-88-3: Draize test, rabbit, eye: 870 ug Mild; Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 435 mg Mild; Draize test, rabbit, skin: 500 mg Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 400 ppm/24H; Inhalation, mouse: LC50 = 30000 mg/m3/2H; Inhalation, mouse: LC50 = 19900 mg/m3/7H; Inhalation, mouse: LC50 = 10000 mg/m3; Inhalation, rat: LC50 = 49 gm/m3/4H; Oral, rat: LD50 = 636 mg/kg; Skin, rabbit: LD50 = 14100 uL/kg.
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 931-51-1.
Carcinogenicity:
Toluene - Not listed by ACGIH, IARC, or NTP.
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Magnesium, chlorocyclohexyl- - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Ecotoxicity:
Fish: Fathead Minnow: LC50 = 2160 mg/L; 96 Hr; Flow through bioassay (pH 7.5)Water flea Daphnia: EC50 =5930 mg/L; 24 HrFish: Pseudomonas putida:

Dispose of in a manner consistent with federal, state, and local regulations.

IATA
Shipping Name: ORGANOMETALLIC COMPOUND DISPERSION, WATER-REACTIVE
, FLAMMABLE, N.O.S.*
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: I
IMO
Shipping Name: ORGANOMETALLIC COMPOUND DISPERSION, WATER-REACTIVE
, FLAMMABLE, N.O.S.
Hazard Class: 4.3 (3)
UN Number: 3207
Packing Group: I
RID/ADR
Shipping Name: ORGANOMETALLIC COMPOUND DISPERSION, WATER-REACTIVE
, FLAMMABLE, N.O.S.
Hazard Class: 4.3 (3)
UN Number: 3207
Packing group: I
USA RQ: CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 14/15 Reacts violently with water liberating
extremely flammable gases.
R 19 May form explosive peroxides.
R 20 Harmful by inhalation.
R 34 Causes burns.
R 63 Possible risk of harm to the unborn child.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 6A Keep under nitrogen.
S 8 Keep container dry.
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 43B In case of fire, use fire-fighting equipment
on basis of sodium chloride, sodium bicarbonate (never
use water).
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
CAS# 109-99-9: 1
CAS# 931-51-1: No information available.
Canada
CAS# 108-88-3 is listed on Canadas DSL List.
CAS# 109-99-9 is listed on Canadas DSL List.
CAS# 931-51-1 is listed on Canadas NDSL List.
CAS# 108-88-3 is listed on Canadas Ingredient Disclosure List.
CAS# 109-99-9 is listed on Canadas Ingredient Disclosure List.
CAS# 931-51-1 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 108-88-3 is listed on the TSCA inventory.
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 931-51-1 is listed on the TSCA inventory.