Name:
Diisopropyl fluorophosphate
Synonym:
DFP; Diisopropyl phosphorofluoridate; Isofluorphat
CAS:
55-91-4
Section 1 - Chemical Product
MSDS Name:Diisopropyl fluorophosphate
Synonym:DFP; Diisopropyl phosphorofluoridate; Isofluorphat
Synonym:DFP; Diisopropyl phosphorofluoridate; Isofluorphat
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 55-91-4 | Diisopropyl fluorophosphate | 100.0 | 200-247-6 |
| Hazard Symbols: T+ Risk Phrases: 26/27/28 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be absorbed through the skin in harmful amounts.
Ingestion:
May be fatal if swallowed.
Inhalation:
Harmful if inhaled. Dust is irritating to the respiratory tract.
Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Causes irritation of mucous membrane.
Chronic:
Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion.
Very toxic by inhalation, in contact with skin and if swallowed.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be absorbed through the skin in harmful amounts.
Ingestion:
May be fatal if swallowed.
Inhalation:
Harmful if inhaled. Dust is irritating to the respiratory tract.
Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Causes irritation of mucous membrane.
Chronic:
Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
For large fires, use water spray, fog, or alcohol-resistant foam.
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Water may be ineffective.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
For large fires, use water spray, fog, or alcohol-resistant foam.
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Water may be ineffective.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Do not exceed 30C (86F).
Wash thoroughly after handling. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Do not exceed 30C (86F).
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use only under a chemical fume hood.
Exposure Limits CAS# 55-91-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use only under a chemical fume hood.
Exposure Limits CAS# 55-91-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: 0.579 mmHg @ 20
Viscosity: Not available.
Boiling Point: 62 deg C @ 9.00mmHg
Freezing/Melting Point: -82 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 1.54 WT% (25C)
Specific Gravity/Density: 1.0550g/cm3
Molecular Formula: C6H14FO3P
Molecular Weight: 184.15
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, moisture, excess heat, temperatures above 30C.
Incompatibilities with Other Materials:
Strong bases - strong oxidizing agents, contact with moisture may generate hydrogen fluoride.
Hazardous Decomposition Products:
Phosphine, carbon monoxide, oxides of phosphorus, carbon dioxide, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, moisture, excess heat, temperatures above 30C.
Incompatibilities with Other Materials:
Strong bases - strong oxidizing agents, contact with moisture may generate hydrogen fluoride.
Hazardous Decomposition Products:
Phosphine, carbon monoxide, oxides of phosphorus, carbon dioxide, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 55-91-4: TE5075000 LD50/LC50:
CAS# 55-91-4: Inhalation, mouse: LC50 = 440 mg/m3/10M; Inhalation, rat: LC50 = 360 mg/m3/10M; Oral, mouse: LD50 = 2 mg/kg; Oral, rabbit: LD50 = 4 mg/kg; Oral, rat: LD50 = 5 mg/kg; Skin, rabbit: LD50 = >117 mg/kg.
Carcinogenicity:
Diisopropyl fluorophosphate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 55-91-4: TE5075000 LD50/LC50:
CAS# 55-91-4: Inhalation, mouse: LC50 = 440 mg/m3/10M; Inhalation, rat: LC50 = 360 mg/m3/10M; Oral, mouse: LD50 = 2 mg/kg; Oral, rabbit: LD50 = 4 mg/kg; Oral, rat: LD50 = 5 mg/kg; Skin, rabbit: LD50 = >117 mg/kg.
Carcinogenicity:
Diisopropyl fluorophosphate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2810
Packing Group: I
IMO
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: I
RID/ADR
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing group: I
USA RQ: CAS# 55-91-4: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 55-91-4: No information available.
Canada
CAS# 55-91-4 is listed on Canadas DSL List.
CAS# 55-91-4 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 55-91-4 is listed on the TSCA inventory.
