Name:
Dimethyl phosphite (Pract) 98% (Titr.)
Synonym:
Bis(hydroxymethyl)phosphine oxide; Dimethoxyphosphine oxide; Dimethyl acid phosphite; Dimethylphosphonate; Dimethyl hydrogen phosphite; Phosphonic acid, dimethyl ester
CAS:
67-56-1
Section 1 - Chemical Product
MSDS Name:Dimethyl phosphite (Pract) 98% (Titr.)
Synonym:Bis(hydroxymethyl)phosphine oxide; Dimethoxyphosphine oxide; Dimethyl acid phosphite; Dimethylphosphonate; Dimethyl hydrogen phosphite; Phosphonic acid, dimethyl ester
Synonym:Bis(hydroxymethyl)phosphine oxide; Dimethoxyphosphine oxide; Dimethyl acid phosphite; Dimethylphosphonate; Dimethyl hydrogen phosphite; Phosphonic acid, dimethyl ester
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 67-56-1 | Methyl alcohol | 0.5 | 200-659-6 |
| Hazard Symbols: XI Risk Phrases: 10 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Effects may be delayed.
Flammable. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Effects may be delayed.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 67-56-1: United Kingdom, WEL - TWA: 200 ppm TWA; 266 mg/m3 TWA United Kingdom, WEL - STEL: 250 ppm STEL; 333 mg/m3 STEL United States OSHA: 200 ppm TWA; 260 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 266 mg/m3 VLE Belgium - STEL: 250 ppm VLE; 333 mg/m3 VLE France - VME: 200 ppm VME; 260 mg/m3 VME France - VLE: 1000 ppm VLE; 1300 mg/m3 VLE Germany: 200 ppm TWA; 270 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 260 mg/m3 OEL Malaysia: 200 ppm TWA; 262 mg/m3 TWA Netherlands: 200 ppm MAC; 260 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 200 ppm VLA-ED; 266 mg/m3 VLA-ED Spain: 250 ppm VLA-EC; 333 mg/m3 VLA-EC CAS# 512-56-1: CAS# 756-79-6: CAS# 868-85-9: Russia: 0.5 mg/m3 TWA Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 67-56-1: United Kingdom, WEL - TWA: 200 ppm TWA; 266 mg/m3 TWA United Kingdom, WEL - STEL: 250 ppm STEL; 333 mg/m3 STEL United States OSHA: 200 ppm TWA; 260 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 266 mg/m3 VLE Belgium - STEL: 250 ppm VLE; 333 mg/m3 VLE France - VME: 200 ppm VME; 260 mg/m3 VME France - VLE: 1000 ppm VLE; 1300 mg/m3 VLE Germany: 200 ppm TWA; 270 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 260 mg/m3 OEL Malaysia: 200 ppm TWA; 262 mg/m3 TWA Netherlands: 200 ppm MAC; 260 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 200 ppm VLA-ED; 266 mg/m3 VLA-ED Spain: 250 ppm VLA-EC; 333 mg/m3 VLA-EC CAS# 512-56-1: CAS# 756-79-6: CAS# 868-85-9: Russia: 0.5 mg/m3 TWA Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: mild odor
pH: Not available.
Vapor Pressure: 4.52 mm Hg @ 25 deg C
Viscosity: Not available.
Boiling Point: 170.5 deg C @ 760 mm Hg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 54 deg C ( 129.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 1.2 g/ml
Molecular Formula: C2H7O3P
Molecular Weight: 110.05
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Ignition sources, moisture, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases, acid chlorides.
Hazardous Decomposition Products:
Phosphine, carbon monoxide, oxides of phosphorus, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Ignition sources, moisture, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases, acid chlorides.
Hazardous Decomposition Products:
Phosphine, carbon monoxide, oxides of phosphorus, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 67-56-1: PC1400000 CAS# 512-56-1: TC8225000 CAS# 756-79-6: SZ9120000 CAS# 868-85-9: SZ7710000 LD50/LC50:
CAS# 67-56-1: Draize test, rabbit, eye: 40 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, rabbit: LC50 = 81000 mg/m3/14H; Inhalation, rat: LC50 = 64000 ppm/4H; Oral, mouse: LD50 = 7300 mg/kg; Oral, rabbit: LD50 = 14200 mg/kg; Oral, rat: LD50 = 5600 mg/kg; Skin, rabbit: LD50 = 15800 mg/kg.
CAS# 512-56-1: Oral, mouse: LD50 = 1470 mg/kg; Oral, rabbit: LD50 = 1275 mg/kg; Oral, rat: LD50 = 840 mg/kg; Skin, rabbit: LD50 = 2830 uL/kg.
CAS# 756-79-6: Oral, mouse: LD50 = >6810 mg/kg; Oral, rat: LD50 = 8210 mg/kg.
CAS# 868-85-9: Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >20 gm/m3; Oral, mouse: LD50 = 1831 mg/kg; Oral, rat: LD50 = 3040 mg/kg; Skin, rabbit: LD50 = 681 mg/kg.
Carcinogenicity:
Methyl alcohol - Not listed by ACGIH, IARC, or NTP.
Trimethylphosphate - California: carcinogen, initial date 5/1/96 Dimethyl methylphosphonate - Not listed by ACGIH, IARC, or NTP.
Dimethyl hydrogen phosphite - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 67-56-1: PC1400000 CAS# 512-56-1: TC8225000 CAS# 756-79-6: SZ9120000 CAS# 868-85-9: SZ7710000 LD50/LC50:
CAS# 67-56-1: Draize test, rabbit, eye: 40 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, rabbit: LC50 = 81000 mg/m3/14H; Inhalation, rat: LC50 = 64000 ppm/4H; Oral, mouse: LD50 = 7300 mg/kg; Oral, rabbit: LD50 = 14200 mg/kg; Oral, rat: LD50 = 5600 mg/kg; Skin, rabbit: LD50 = 15800 mg/kg.
CAS# 512-56-1: Oral, mouse: LD50 = 1470 mg/kg; Oral, rabbit: LD50 = 1275 mg/kg; Oral, rat: LD50 = 840 mg/kg; Skin, rabbit: LD50 = 2830 uL/kg.
CAS# 756-79-6: Oral, mouse: LD50 = >6810 mg/kg; Oral, rat: LD50 = 8210 mg/kg.
CAS# 868-85-9: Draize test, rabbit, eye: 20 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >20 gm/m3; Oral, mouse: LD50 = 1831 mg/kg; Oral, rat: LD50 = 3040 mg/kg; Skin, rabbit: LD50 = 681 mg/kg.
Carcinogenicity:
Methyl alcohol - Not listed by ACGIH, IARC, or NTP.
Trimethylphosphate - California: carcinogen, initial date 5/1/96 Dimethyl methylphosphonate - Not listed by ACGIH, IARC, or NTP.
Dimethyl hydrogen phosphite - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 10 Flammable.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 33 Take precautionary measures against static
discharges.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 67-56-1: 1
CAS# 512-56-1: 1
CAS# 756-79-6: 1
CAS# 868-85-9: 1
Canada
CAS# 67-56-1 is listed on Canadas DSL List.
CAS# 512-56-1 is listed on Canadas DSL List.
CAS# 756-79-6 is listed on Canadas DSL List.
CAS# 868-85-9 is listed on Canadas NDSL List.
CAS# 67-56-1 is listed on Canadas Ingredient Disclosure List.
CAS# 512-56-1 is listed on Canadas Ingredient Disclosure List.
CAS# 756-79-6 is not listed on Canadas Ingredient Disclosure List.
CAS# 868-85-9 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-56-1 is listed on the TSCA inventory.
CAS# 512-56-1 is listed on the TSCA inventory.
CAS# 756-79-6 is listed on the TSCA inventory.
CAS# 868-85-9 is listed on the TSCA inventory.
