Name:
Dimethyl phthalate p.a.
Synonym:
Dimethyl 1,2-benzenedicarboxylate; Phthalic acid, dimethyl ester; DMP; plasticizer; Palatinol M; Fermine; Avolin; Mipax; Dimethyl o-phthalate
CAS:
131-11-3
Section 1 - Chemical Product
MSDS Name:Dimethyl phthalate p.a.
Synonym:Dimethyl 1,2-benzenedicarboxylate; Phthalic acid, dimethyl ester; DMP; plasticizer; Palatinol M; Fermine; Avolin; Mipax; Dimethyl o-phthalate
Synonym:Dimethyl 1,2-benzenedicarboxylate; Phthalic acid, dimethyl ester; DMP; plasticizer; Palatinol M; Fermine; Avolin; Mipax; Dimethyl o-phthalate
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 131-11-3 | Dimethyl phthalate | > 99.5 | 205-011-6 |
| Hazard Symbols: XI Risk Phrases: 36/37 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes and respiratory system.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause transient corneal injury.
Skin:
Prolonged and/or repeated contact may cause irritation and/or dermatitis. Dimethyl phthalate has low acute toxicity in experimental animals exposed by the oral, inhalation and dermal routes. In other words, it is not acutely toxic. However, repeated and/or prolonged skin contact may result in the absorption of harmful amounts. Dimethyl phthalate was not a sensitizer in guinea pigs and has not been reported to be a sensitizer from its use during WWII as an insect repellent; however, it has been called an allergen in one Russian study of human patch testing.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Exposure to dimethyl phthalate occurs from spray or mist, rather than from the vapor, unless heat is applied. Intermittent exposure produced blood, liver and kidney changes in rats.
Chronic:
Some adverse reproductive effects were seen in animal studies. Few defects occurred when rats were given injections of dimethyl phthalate intraperitoneally on gestational days 5, 10 and 15.
Irritating to eyes and respiratory system.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause transient corneal injury.
Skin:
Prolonged and/or repeated contact may cause irritation and/or dermatitis. Dimethyl phthalate has low acute toxicity in experimental animals exposed by the oral, inhalation and dermal routes. In other words, it is not acutely toxic. However, repeated and/or prolonged skin contact may result in the absorption of harmful amounts. Dimethyl phthalate was not a sensitizer in guinea pigs and has not been reported to be a sensitizer from its use during WWII as an insect repellent; however, it has been called an allergen in one Russian study of human patch testing.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Exposure to dimethyl phthalate occurs from spray or mist, rather than from the vapor, unless heat is applied. Intermittent exposure produced blood, liver and kidney changes in rats.
Chronic:
Some adverse reproductive effects were seen in animal studies. Few defects occurred when rats were given injections of dimethyl phthalate intraperitoneally on gestational days 5, 10 and 15.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid breathing spray or mist.
Storage:
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid breathing spray or mist.
Storage:
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 131-11-3: United Kingdom, OES - TWA: 5 mg/m3 TWA United Kingdom, OES - STEL: 10 mg/m3 STEL United States OSHA: 5 mg/m3 TWA Belgium - TWA: 5 mg/m3 VLE France - VME: 5 mg/m3 VME Malaysia: 5 mg/m3 TWA Russia: 0.3 mg/m3 TWA Spain: 5 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 131-11-3: United Kingdom, OES - TWA: 5 mg/m3 TWA United Kingdom, OES - STEL: 10 mg/m3 STEL United States OSHA: 5 mg/m3 TWA Belgium - TWA: 5 mg/m3 VLE France - VME: 5 mg/m3 VME Malaysia: 5 mg/m3 TWA Russia: 0.3 mg/m3 TWA Spain: 5 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless to light yellow
Odor: ester-like - weak odor
pH: Not available.
Vapor Pressure: .0015 mm Hg @ deg 20
Viscosity: 17.2 cP 25 deg C
Boiling Point: 282 deg C
Freezing/Melting Point: 2 deg C
Autoignition Temperature: 460 deg C ( 860.00 deg F)
Flash Point: 295 deg F ( 146.11 deg C)
Explosion Limits, lower: 0.9
Explosion Limits, upper: 8.0%
Decomposition Temperature: Not available.
Solubility in water: 0.4% (20 C) in water.
Specific Gravity/Density: 1.19
Molecular Formula: C10H10O4
Molecular Weight: 194.19
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
No specific conditions to avoid noted.
Incompatibilities with Other Materials:
Oxidizing agents, acids, bases, and nitrates.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable.
Conditions to Avoid:
No specific conditions to avoid noted.
Incompatibilities with Other Materials:
Oxidizing agents, acids, bases, and nitrates.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 131-11-3: TI1575000 LD50/LC50:
CAS# 131-11-3: Dermal, guinea pig: LD50 = >10 mL/kg; Draize test, rabbit, eye: 119 mg; Oral, mouse: LD50 = 6800 mg/kg; Oral, rabbit: LD50 = 4400 uL/kg; Oral, rat: LD50 = 6800 mg/kg; Skin, rabbit: LD50 = >20 mL/kg; Skin, rat: LD50 = >4800 mg/kg.
Carcinogenicity:
Dimethyl phthalate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 131-11-3: TI1575000 LD50/LC50:
CAS# 131-11-3: Dermal, guinea pig: LD50 = >10 mL/kg; Draize test, rabbit, eye: 119 mg; Oral, mouse: LD50 = 6800 mg/kg; Oral, rabbit: LD50 = 4400 uL/kg; Oral, rat: LD50 = 6800 mg/kg; Skin, rabbit: LD50 = >20 mL/kg; Skin, rat: LD50 = >4800 mg/kg.
Carcinogenicity:
Dimethyl phthalate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 131-11-3: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37 Irritating to eyes and respiratory system.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 39 Wear eye/face protection.
WGK (Water Danger/Protection)
CAS# 131-11-3: 1
Canada
CAS# 131-11-3 is listed on Canadas DSL List.
CAS# 131-11-3 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 131-11-3 is listed on the TSCA inventory.
