Name:
DMSO/NMP (Dimethylsulfoxide/1-Methyl-2-pyrrolidone)
Synonym:
CAS:
67-68-5
Section 1 - Chemical Product
MSDS Name:DMSO/NMP (Dimethylsulfoxide/1-Methyl-2-pyrrolidone)
Synonym:
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 67-68-5 | Dimethylsulfoxide | 81% | 200-664-3 |
| Hazard Symbols: XI Risk Phrases: 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).Light sensitive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).Light sensitive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustible liquid.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustible liquid.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container.
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 67-68-5: Germany: 160 mg/m3 TWA Germany: Skin absorber Netherlands: 50 ppm MAC; 150 mg/m3 MAC Russia: 20 mg/m3 TWA CAS# 872-50-4: United Kingdom, WEL - TWA: 25 ppm TWA; 103 mg/m3 TWA United Kingdom, WEL - STEL: 75 ppm STEL; 309 mg/m3 STEL Germany: 19 ppm TWA (steam); 80 mg/m3 TWA (steam) Germany: Skin absorber Japan: 1 ppm OEL; 4 mg/m3 OEL Netherlands: 20 ppm MAC; 80 mg/m3 MAC (fume) Russia: 100 mg/m3 TWA Spain: 25 ppm VLA-ED; 103 mg/m3 VLA-ED Spain: 75 ppm VLA-EC; 309 mg/m3 VLA-EC Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 67-68-5: Germany: 160 mg/m3 TWA Germany: Skin absorber Netherlands: 50 ppm MAC; 150 mg/m3 MAC Russia: 20 mg/m3 TWA CAS# 872-50-4: United Kingdom, WEL - TWA: 25 ppm TWA; 103 mg/m3 TWA United Kingdom, WEL - STEL: 75 ppm STEL; 309 mg/m3 STEL Germany: 19 ppm TWA (steam); 80 mg/m3 TWA (steam) Germany: Skin absorber Japan: 1 ppm OEL; 4 mg/m3 OEL Netherlands: 20 ppm MAC; 80 mg/m3 MAC (fume) Russia: 100 mg/m3 TWA Spain: 25 ppm VLA-ED; 103 mg/m3 VLA-ED Spain: 75 ppm VLA-EC; 309 mg/m3 VLA-EC Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: garlic-like odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: > 85 deg C (> 185.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials, light, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, reducing agents, acids, metals.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.
Hazardous Polymerization: Has not been reported
Not available.
Conditions to Avoid:
Incompatible materials, light, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, reducing agents, acids, metals.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, sulfur oxides (SOx), including sulfur oxide and sulfur dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 67-68-5: PV6210000 CAS# 872-50-4: UY5790000 LD50/LC50:
CAS# 67-68-5: Draize test, rabbit, eye: 100 mg; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, mouse: LD50 = 7920 mg/kg; Oral, rat: LD50 = 14500 mg/kg; Skin, rat: LD50 = 40 gm/kg.
CAS# 872-50-4: Draize test, rabbit, eye: 100 mg Moderate; Oral, mouse: LD50 = 5130 mg/kg; Oral, rat: LD50 = 3914 mg/kg; Skin, rabbit: LD50 = 8 gm/kg.
Carcinogenicity:
Dimethylsulfoxide - Not listed by ACGIH, IARC, or NTP.
1-Methyl-2-pyrrolidone - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 67-68-5: PV6210000 CAS# 872-50-4: UY5790000 LD50/LC50:
CAS# 67-68-5: Draize test, rabbit, eye: 100 mg; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Oral, mouse: LD50 = 7920 mg/kg; Oral, rat: LD50 = 14500 mg/kg; Skin, rat: LD50 = 40 gm/kg.
CAS# 872-50-4: Draize test, rabbit, eye: 100 mg Moderate; Oral, mouse: LD50 = 5130 mg/kg; Oral, rat: LD50 = 3914 mg/kg; Skin, rabbit: LD50 = 8 gm/kg.
Carcinogenicity:
Dimethylsulfoxide - Not listed by ACGIH, IARC, or NTP.
1-Methyl-2-pyrrolidone - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 41 In case of fire and/or explosion do not breathe
fumes.
WGK (Water Danger/Protection)
CAS# 67-68-5: 1
CAS# 872-50-4: 1
Canada
CAS# 67-68-5 is listed on Canadas DSL List.
CAS# 872-50-4 is listed on Canadas DSL List.
CAS# 67-68-5 is listed on Canadas Ingredient Disclosure List.
CAS# 872-50-4 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-68-5 is listed on the TSCA inventory.
CAS# 872-50-4 is listed on the TSCA inventory.
