Name:
Ethyl chloroacetate p.a.
Synonym:
Chloroacetic acid ethyl ester; Ethyl alpha-chloroacetate; Ethyl chlorethanoate; Ethyl monochloroacetate; Acetic acid, chloro-, ethyl este
CAS:
105-39-5
Section 1 - Chemical Product
MSDS Name:Ethyl chloroacetate p.a.
Synonym:Chloroacetic acid ethyl ester; Ethyl alpha-chloroacetate; Ethyl chlorethanoate; Ethyl monochloroacetate; Acetic acid, chloro-, ethyl este
Synonym:Chloroacetic acid ethyl ester; Ethyl alpha-chloroacetate; Ethyl chlorethanoate; Ethyl monochloroacetate; Acetic acid, chloro-, ethyl este
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 105-39-5 | Ethyl cloroacetate, p.a. | 100 | 203-294-0 |
| Hazard Symbols: T N Risk Phrases: 10 23/24/25 50 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Toxic by inhalation, in contact with skin and if swallowed. Very toxic to aquatic organisms.Lachrymator (substance which increases the flow of tears).Dangerous for the environment.
Potential Health Effects
Eye:
Causes severe eye irritation. Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. Causes digestive tract irritation.
Inhalation:
Causes respiratory tract irritation. Vapors may cause dizziness or suffocation. Harmful if inhaled.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Halogenated acid ester compounds have the potential to produce pulmonary edema.
Flammable. Toxic by inhalation, in contact with skin and if swallowed. Very toxic to aquatic organisms.Lachrymator (substance which increases the flow of tears).Dangerous for the environment.
Potential Health Effects
Eye:
Causes severe eye irritation. Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. Causes digestive tract irritation.
Inhalation:
Causes respiratory tract irritation. Vapors may cause dizziness or suffocation. Harmful if inhaled.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Halogenated acid ester compounds have the potential to produce pulmonary edema.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Skin:
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May ignite or explode on contact with steam or moist air.
Extinguishing Media:
Use water spray to cool fire-exposed containers. DO NOT USE WATER! For large fires, use water spray, fog or alcohol-resistant foam. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Contact professional fire-fighters immediately.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors may form an explosive mixture with air. Vapors can travel to a source of ignition and flash back. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May ignite or explode on contact with steam or moist air.
Extinguishing Media:
Use water spray to cool fire-exposed containers. DO NOT USE WATER! For large fires, use water spray, fog or alcohol-resistant foam. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Contact professional fire-fighters immediately.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not expose spill to water. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not expose spill to water. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Flammables-area.
Wash thoroughly after handling. Do not allow water to get into the container because of violent reaction. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Do not allow contact with water. Use only in a chemical fume hood. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water. Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: clear, colorless - colorless liquid
Odor: pungent odor - fruity odor
pH: Not available.
Vapor Pressure: 3.3 mm Hg @ 20 C
Viscosity: Not available.
Boiling Point: 144 deg C @ 760.00mm Hg
Freezing/Melting Point: -27 deg C
Autoignition Temperature: Not available.
Flash Point: 54 deg C ( 129.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density: 1.1450g/cm3
Molecular Formula: C4H7ClO2
Molecular Weight: 122.55
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Combines vigorously or explosively with water. Volatile in steam.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, exposure to moist air or water, steam.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, strong bases, strong acids.
Hazardous Decomposition Products:
Hydrogen chloride, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Combines vigorously or explosively with water. Volatile in steam.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, exposure to moist air or water, steam.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, strong bases, strong acids.
Hazardous Decomposition Products:
Hydrogen chloride, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 105-39-5: AF9110000 LD50/LC50:
CAS# 105-39-5: Draize test, rabbit, eye: 250 ug Severe; Draize test, rabbit, eye: 250 ug/24H Severe; Inhalation, rat: LC50 = 3330 uL/m3/4H; Oral, mouse: LD50 = 350 mg/kg; Oral, rat: LD50 = 180 mg/kg; Skin, rabbit: LD50 = 230 mg/kg; Skin, rat: LD50 = 161 mg/kg.
Carcinogenicity:
Ethyl cloroacetate, p.a. - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
CAS# 105-39-5: AF9110000 LD50/LC50:
CAS# 105-39-5: Draize test, rabbit, eye: 250 ug Severe; Draize test, rabbit, eye: 250 ug/24H Severe; Inhalation, rat: LC50 = 3330 uL/m3/4H; Oral, mouse: LD50 = 350 mg/kg; Oral, rat: LD50 = 180 mg/kg; Skin, rabbit: LD50 = 230 mg/kg; Skin, rat: LD50 = 161 mg/kg.
Carcinogenicity:
Ethyl cloroacetate, p.a. - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Ethyl chloroacetate is not expected to adsorb to sediments in water or bioconcentrate in fish and no significant volatilization is expected to occur. It is expected to leach extensively in soil and reach the ground water where it sould hydrolyze completely. Ethyl chloroacetate is also expected to degrade ultimately to small, oxygenated organic molecules in the atmosphere.
Ethyl chloroacetate is not expected to adsorb to sediments in water or bioconcentrate in fish and no significant volatilization is expected to occur. It is expected to leach extensively in soil and reach the ground water where it sould hydrolyze completely. Ethyl chloroacetate is also expected to degrade ultimately to small, oxygenated organic molecules in the atmosphere.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ETHYL CHLOROACETATE
Hazard Class: 6.1
UN Number: 1181
Packing Group: II
IMO
Shipping Name: ETHYL CHLOROACETATE
Hazard Class: 6.1
UN Number: 1181
Packing Group: II
RID/ADR
Shipping Name: ETHYL CHLOROACETATE
Dangerous Goods Code: 6.1(16B)
UN Number: 1181
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 10 Flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 105-39-5: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 105-39-5 is listed on Canadas DSL List.
CAS# 105-39-5 is listed on Canadas Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 105-39-5 is listed on the TSCA inventory.
