Name:
Ethyl Ether
Synonym:
Ethane, 1,1-oxybis-; Anesthetic ether; Diethyl ether; Ethoxyethane; Diethyl oxide; Ethyl ether; Ether; Ethyl oxide
CAS:
60-29-7
Section 1 - Chemical Product
MSDS Name:Ethyl Ether
Synonym:Ethane, 1,1-oxybis-; Anesthetic ether; Diethyl ether; Ethoxyethane; Diethyl oxide; Ethyl ether; Ether; Ethyl oxide
Synonym:Ethane, 1,1-oxybis-; Anesthetic ether; Diethyl ether; Ethoxyethane; Diethyl oxide; Ethyl ether; Ether; Ethyl oxide
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 60-29-7 | Ethyl ether | > 98 | 200-467-2 |
| Hazard Symbols: XN F+ Risk Phrases: |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Extremely flammable. May form explosive peroxides. Harmful if swallowed. Repeated exposure may cause skin dryness or cracking.
Vapors may cause drowsiness and dizziness.Hygroscopic.Air sensitive.Light sensitive.
Potential Health Effects
Eye:
Causes moderate eye irritation. Causes redness and pain.
Skin:
Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
Aspiration hazard. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Exposure to high concentrations may produce narcosis, nausea and loss of consciousness. Inhalation of vapors may cause drowsiness and dizziness.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure to high vapor concentrations may cause eye injury. Repeated exposures may be habit forming.
Extremely flammable. May form explosive peroxides. Harmful if swallowed. Repeated exposure may cause skin dryness or cracking.
Vapors may cause drowsiness and dizziness.Hygroscopic.Air sensitive.Light sensitive.
Potential Health Effects
Eye:
Causes moderate eye irritation. Causes redness and pain.
Skin:
Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
Aspiration hazard. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Exposure to high concentrations may produce narcosis, nausea and loss of consciousness. Inhalation of vapors may cause drowsiness and dizziness.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure to high vapor concentrations may cause eye injury. Repeated exposures may be habit forming.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat symptomatically and supportively.
Skin:
In case of contact, immediately flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool.
Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. May form explosive peroxides. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished.
Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool.
Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. May form explosive peroxides. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished.
Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as saw dust. Use a spark-proof tool.
Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as saw dust. Use a spark-proof tool.
Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges.
Keep container tightly closed. Avoid contact with heat, sparks and flame. Handle under an inert atmosphere. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Avoid breathing vapor.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Do not expose to air. Store protected from light.
Store under an inert atmosphere. Keep away from oxidizing agents.
Store at room temperature or below. Do not exceed 86F. Do not open unless emsdss are at 72F or below for at least 24 hours. Ethyl ether may form explosive peroxides on long standing or after exposure to air or light.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges.
Keep container tightly closed. Avoid contact with heat, sparks and flame. Handle under an inert atmosphere. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation.
Avoid breathing vapor.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Do not expose to air. Store protected from light.
Store under an inert atmosphere. Keep away from oxidizing agents.
Store at room temperature or below. Do not exceed 86F. Do not open unless emsdss are at 72F or below for at least 24 hours. Ethyl ether may form explosive peroxides on long standing or after exposure to air or light.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Use explosion-proof ventilation equipment.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Personal Protective Equipment Eyes: Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Use explosion-proof ventilation equipment.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Personal Protective Equipment Eyes: Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Clear liquid
Color: APHA: 10 max
Odor: sweetish odor - aromatic odor
pH: Not available.
Vapor Pressure: 442 mm Hg @ 20C
Viscosity: 0.2448 cp @ 20C
Boiling Point: 34.6 deg C
Freezing/Melting Point: -116.3 deg C
Autoignition Temperature: 180-190 deg C
Flash Point: -45 deg C ( -49.00 deg F)
Explosion Limits, lower: 1.9 vol %
Explosion Limits, upper: 36.0 vol %
Decomposition Temperature:
Solubility in water: Slightly soluble.
Specific Gravity/Density: 0.7110g/cm3
Molecular Formula: C4H10O
Molecular Weight: 74.12
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Prolonged exposure to air and sunlight may form unstable peroxides.
Conditions to Avoid:
Light, ignition sources, exposure to air, electrical sparks, exposure to flame, heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, bromine trifluoride, chlorine trifluoride, halogens, nitric acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen peroxides, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate, moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid, peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, peroxides.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures. Prolonged exposure to air and sunlight may form unstable peroxides.
Conditions to Avoid:
Light, ignition sources, exposure to air, electrical sparks, exposure to flame, heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, bromine trifluoride, chlorine trifluoride, halogens, nitric acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen peroxides, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate, moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid, peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, peroxides.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 60-29-7: KI5775000 CAS# 128-37-0: GO7875000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 128-37-0: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/48H Moderate; Oral, mouse: LD50 = 650 mg/kg; Oral, rat: LD50 = 890 mg/kg.
CAS# 7732-18-5.
Carcinogenicity:
Ethyl ether - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Butylated hydroxy toluene - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Water - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
CAS# 60-29-7: KI5775000 CAS# 128-37-0: GO7875000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 128-37-0: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/48H Moderate; Oral, mouse: LD50 = 650 mg/kg; Oral, rat: LD50 = 890 mg/kg.
CAS# 7732-18-5.
Carcinogenicity:
Ethyl ether - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Butylated hydroxy toluene - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Water - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox testIf ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; Microtox testIf ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN F+
Risk Phrases:
R 12 Extremely flammable.
R 19 May form explosive peroxides.
R 22 Harmful if swallowed.
R 66 Repeated exposure may cause skin dryness or
cracking.
R 67 Vapors may cause drowsiness and dizziness.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 60-29-7: 1
CAS# 128-37-0: 1
CAS# 7732-18-5: No information available.
United Kingdom Occupational Exposure Limits
United Kingdom Maximum Exposure Limits
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 60-29-7 is not listed on Canadas Ingredient Disclosure List.
CAS# 128-37-0 is not listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 60-29-7: OEL-AUSTRALIA:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (150
0 mg/m3)
OEL-AUSTRIA:TWA 400 ppm (1200 mg/m3)
OEL-BELGIUM:TWA 400 ppm (1210 mg/m3);STEL 500 ppm (1520 mg/m3)
OEL-CZECHOSLOVAKIA:TWA 500 mg/m3;STEL 1500 mg/m3
OEL-DENMARK:TWA 400 ppm (1200 mg/m3)
OEL-FINLAND:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3)
OEL-FRANCE:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3)
OEL-GERMANY:TWA 400 ppm (1200 mg/m3)
OEL-HUNGARY:TWA 300 mg/m3;STEL 600 mg/m3;Skin
OEL-JAPAN:TWA 400 ppm (1200 mg/m3)
OEL-THE NETHERLANDS:TWA 400 ppm (1200 mg/m3) JAN9
OEL-THE PHILIPPINES:TWA 400 ppm (1200 mg/m3) JAN9
OEL-POLAND:TWA 300 mg/m3
OEL-RUSSIA:TWA 400 ppm;STEL 300 mg/m3
OEL-SWEDEN:TWA 400 ppm (1200 mg/m3);STEL 500 ppm (1500 mg/m3)
OEL-SWITZERLAND:TWA 400 ppm (1200 mg/m3);STEL 800 ppm
OEL-TURKEY:TWA 400 ppm (1200 mg/m3)
OEL-UNITED KINGDOM:TWA 400 ppm (1200 mg/m3);STEL 500 ppm
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
CAS# 128-37-0: OEL-AUSTRALIA:TWA 10 mg/m3
OEL-BELGIUM:TWA 10 mg/m3
OEL-FINLAND:TWA 10 mg/m3;STEL 20 mg/m3;Skin
OEL-FRANCE:TWA 10 mg/m3
OEL-THE NETHERLANDS:TWA 10 mg/m3
OEL-SWITZERLAND:TWA 10 mg/m3
OEL-UNITED KINGDOM:TWA 10 mg/m3
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 60-29-7 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 128-37-0 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 7732-18-5 is not listed on the TSCA inventory.
It is for research and development use only.
