Name:
Ethylene glycol monomethyl ether
Synonym:
Methyl Cellosolve; Ethylene glycol methyl ether; EGME; 2-Methoxyethanol; 2-ME
CAS:
109-86-4
Section 1 - Chemical Product
MSDS Name:Ethylene glycol monomethyl ether
Synonym:Methyl Cellosolve; Ethylene glycol methyl ether; EGME; 2-Methoxyethanol; 2-ME
Synonym:Methyl Cellosolve; Ethylene glycol methyl ether; EGME; 2-Methoxyethanol; 2-ME
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 109-86-4 | Ethylene glycol monomethyl ether | >98 | 203-713-7 |
| Hazard Symbols: T Risk Phrases: 10 20/21/22 60 61 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Harmful by inhalation, in contact with skin and if swallowed. May impair fertility. May cause harm to the unborn child.
Potential Health Effects
Eye:
May cause transient corneal injury. Causes redness and pain.
Skin:
May be harmful if absorbed through the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause effects similar to those of acute inhalation. Ingestion of large amounts may cause CNS depression.
Inhalation:
Causes respiratory tract irritation. May cause liver and kidney damage. May cause anemia. May cause drowsiness, unconsciousness, and central nervous system depression. Central nervous system effects may include confusion, ataxia (failure of muscular coordination), vertigo, tinnitus, weakness, disorientation, lethargy, drowsiness, and finally coma. Vapors may cause dizziness or suffocation.
Chronic:
Prolonged or repeated exposure may cause adverse reproductive effects. Chronic exposure may cause effects similar to those of acute exposure.
Flammable. Harmful by inhalation, in contact with skin and if swallowed. May impair fertility. May cause harm to the unborn child.
Potential Health Effects
Eye:
May cause transient corneal injury. Causes redness and pain.
Skin:
May be harmful if absorbed through the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. May cause effects similar to those of acute inhalation. Ingestion of large amounts may cause CNS depression.
Inhalation:
Causes respiratory tract irritation. May cause liver and kidney damage. May cause anemia. May cause drowsiness, unconsciousness, and central nervous system depression. Central nervous system effects may include confusion, ataxia (failure of muscular coordination), vertigo, tinnitus, weakness, disorientation, lethargy, drowsiness, and finally coma. Vapors may cause dizziness or suffocation.
Chronic:
Prolonged or repeated exposure may cause adverse reproductive effects. Chronic exposure may cause effects similar to those of acute exposure.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. May form explosive peroxides. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. May form explosive peroxides. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Keep under a nitrogen blanket. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Containers should be dated when opened and tested periodically for the presence of peroxides. Should crystals form in a peroxidizable liquid, peroxidation may have occurred and the product should be considered extremely dangerous. In this instance, the container should only be opened remotely by professionals. All peroxidizable substances should be stored away from heat and light and be protected from ignition sources.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 109-86-4: United Kingdom, WEL - TWA: 5 ppm TWA; 16 mg/m3 TWA United Kingdom, WEL - STEL: 15 ppm STEL; 48 mg/m3 STEL United States OSHA: 25 ppm TWA; 80 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 16 mg/m3 VLE France - VME: 5 ppm VME; 16 mg/m3 VME Germany: 5 ppm TWA; 16 mg/m3 TWA Germany: Skin absorber Japan: 5 ppm OEL; 16 mg/m3 OEL Malaysia: 5 ppm TWA; 16 mg/m3 TWA Netherlands: 0.3 ppm MAC; 1 mg/m3 MAC Spain: 5 ppm VLA-ED; 16 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 109-86-4: United Kingdom, WEL - TWA: 5 ppm TWA; 16 mg/m3 TWA United Kingdom, WEL - STEL: 15 ppm STEL; 48 mg/m3 STEL United States OSHA: 25 ppm TWA; 80 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 16 mg/m3 VLE France - VME: 5 ppm VME; 16 mg/m3 VME Germany: 5 ppm TWA; 16 mg/m3 TWA Germany: Skin absorber Japan: 5 ppm OEL; 16 mg/m3 OEL Malaysia: 5 ppm TWA; 16 mg/m3 TWA Netherlands: 0.3 ppm MAC; 1 mg/m3 MAC Spain: 5 ppm VLA-ED; 16 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: mild odor - ethereal odor
pH: Not available.
Vapor Pressure: 9.5 mm Hg @ 25 deg C
Viscosity: 1.98 cps @ 20 deg C
Boiling Point: 124 deg C @ 760 mm Hg
Freezing/Melting Point: -85 deg C
Autoignition Temperature: 285 deg C ( 545.00 deg F)
Flash Point: 38 deg C ( 100.40 deg F)
Explosion Limits, lower: 1.8 vol %
Explosion Limits, upper: 19.8 vol %
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: .9600 g/ml
Molecular Formula: C3H8O2
Molecular Weight: 76.09
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
Light, ignition sources, exposure to air, heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, alkalies.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
Light, ignition sources, exposure to air, heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, alkalies.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 109-86-4: KL5775000 LD50/LC50:
CAS# 109-86-4: Draize test, rabbit, eye: 97 mg; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 483 mg/24H Mild; Inhalation, mouse: LC50 = 1480 ppm/7H; Inhalation, rat: LC50 = 1500 ppm/7H; Oral, mouse: LD50 = 2560 mg/kg; Oral, mouse: LD50 = 2800 mg/kg; Oral, rabbit: LD50 = 890 mg/kg; Oral, rat: LD50 = 2370 mg/kg; Oral, rat: LD50 = 2460 mg/kg; Skin, rabbit: LD50 = 1280 mg/kg; Skin, rabbit: LD50 = 2000 mg/kg.
Inhalation, rat: LC50 = 1500 ppm/7H = 1984 ppm/4H (calculated).
LDLo: 3380 mg/kg (RTECS).
Carcinogenicity:
Ethylene glycol monomethyl ether - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 109-86-4: KL5775000 LD50/LC50:
CAS# 109-86-4: Draize test, rabbit, eye: 97 mg; Draize test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 483 mg/24H Mild; Inhalation, mouse: LC50 = 1480 ppm/7H; Inhalation, rat: LC50 = 1500 ppm/7H; Oral, mouse: LD50 = 2560 mg/kg; Oral, mouse: LD50 = 2800 mg/kg; Oral, rabbit: LD50 = 890 mg/kg; Oral, rat: LD50 = 2370 mg/kg; Oral, rat: LD50 = 2460 mg/kg; Skin, rabbit: LD50 = 1280 mg/kg; Skin, rabbit: LD50 = 2000 mg/kg.
Inhalation, rat: LC50 = 1500 ppm/7H = 1984 ppm/4H (calculated).
LDLo: 3380 mg/kg (RTECS).
Carcinogenicity:
Ethylene glycol monomethyl ether - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Rainbow trout: LC50 = 15,520 mg/L; 96 Hr.; 12 degrees CFish: Bluegill/Sunfish: LC50 = 10,000 mg/L; 96 Hr.; Static Condition, 23 degrees C
Fish: Rainbow trout: LC50 = 15,520 mg/L; 96 Hr.; 12 degrees CFish: Bluegill/Sunfish: LC50 = 10,000 mg/L; 96 Hr.; Static Condition, 23 degrees C
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ETHYLENE GLYCOL MONOMETHYL ETHER
Hazard Class: 3
UN Number: 1188
Packing Group: III
IMO
Shipping Name: ETHYLENE GLYCOL MONOMETHYL ETHER
Hazard Class: 3.3
UN Number: 1188
Packing Group: III
RID/ADR
Shipping Name: ETHYLENE GLYCOL MONOMETHYL ETHER
Hazard Class: 3
UN Number: 1188
Packing group: III
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 61 May cause harm to the unborn child.
R 10 Flammable.
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 60 May impair fertility.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 109-86-4: 1
Canada
CAS# 109-86-4 is listed on Canadas DSL List.
CAS# 109-86-4 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-86-4 is listed on the TSCA inventory.
