Name:
Ethylenediamine Tetraacetic Acid
Synonym:
Acetic acid, (ethylenedinitrilo)tetra-; 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-; Edetic acid; EDTA; EDTA (chelating agent); EDTA acid; Endrate; N,N-1,2-Ethanediylbis(N-(carboxymethyl)glycine); Ethylenediaminetetraacetic acid; E
CAS:
60-00-4
Section 1 - Chemical Product
MSDS Name:Ethylenediamine Tetraacetic Acid
Synonym:Acetic acid, (ethylenedinitrilo)tetra-; 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-; Edetic acid; EDTA; EDTA (chelating agent); EDTA acid; Endrate; N,N-1,2-Ethanediylbis(N-(carboxymethyl)glycine); Ethylenediaminetetraacetic acid; E
Synonym:Acetic acid, (ethylenedinitrilo)tetra-; 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-; Edetic acid; EDTA; EDTA (chelating agent); EDTA acid; Endrate; N,N-1,2-Ethanediylbis(N-(carboxymethyl)glycine); Ethylenediaminetetraacetic acid; E
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 60-00-4 | Ethylenediamine tetraacetic acid | >99 | 200-449-4 |
| Hazard Symbols: XI Risk Phrases: 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. Causes redness and pain.
Skin:
Causes skin irritation. Causes redness and pain.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts can cause hypocalcemic tetany due to formation of calcium complexes. Exposure may cause kidney injury, muscle cramps, bone-marrow depression, and a generalized allergic reaction.
Inhalation:
Causes irritation of the mucous membrane and upper respiratory tract.
Chronic:
May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause kidney damage.
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. Causes redness and pain.
Skin:
Causes skin irritation. Causes redness and pain.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts can cause hypocalcemic tetany due to formation of calcium complexes. Exposure may cause kidney injury, muscle cramps, bone-marrow depression, and a generalized allergic reaction.
Inhalation:
Causes irritation of the mucous membrane and upper respiratory tract.
Chronic:
May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. Chronic exposure may cause kidney damage.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid breathing dust.
Storage:
Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid breathing dust.
Storage:
Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 60-00-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 60-00-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystals
Color: colorless to white
Odor: odorless
pH: Not available.
Vapor Pressure: Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 220 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 240 deg C
Solubility in water: Slightly soluble.
Specific Gravity/Density: 0.86 @ 20C
Molecular Formula: C10H16N2O8
Molecular Weight: 292.25
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Decarboxylates above 150C.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, aluminum, copper, copper alloys, nickel.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Stable at room temperature in closed containers under normal storage and handling conditions. Decarboxylates above 150C.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, aluminum, copper, copper alloys, nickel.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 60-00-4: AH4025000 LD50/LC50:
CAS# 60-00-4: Oral, mouse: LD50 = 30 mg/kg.
Carcinogenicity:
Ethylenediamine tetraacetic acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 60-00-4: AH4025000 LD50/LC50:
CAS# 60-00-4: Oral, mouse: LD50 = 30 mg/kg.
Carcinogenicity:
Ethylenediamine tetraacetic acid - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Channel catfish: LC50 = 129-159 mg/L; 96Hr; UnspecifiedFish: Rainbow trout: LC50 = 340 mg/L; 24Hr; UnspecifiedFish: Bluegill/Sunfish: LC50 = 129-159 mg/L; 96Hr; UnspecifiedFish: Fathead Minnow: 100% Lethal = 750 ppm; 96 Hr; Static bioassayWater flea Daphnia: LC50 > 100 ppm; 96 Hr; Static bioassayIf released to soil, EDTA is expected to complex with trace metals and alkaline earth metals present in the soil, thereby causing an increase in the total solubility of the metals. EDTA may eventually predominate as the Fe(III) chelate in acidic soils and as the Ca chelate in alkaline soils. Biodegradation of EDTA in aerobic soils is the dominant
Fish: Channel catfish: LC50 = 129-159 mg/L; 96Hr; UnspecifiedFish: Rainbow trout: LC50 = 340 mg/L; 24Hr; UnspecifiedFish: Bluegill/Sunfish: LC50 = 129-159 mg/L; 96Hr; UnspecifiedFish: Fathead Minnow: 100% Lethal = 750 ppm; 96 Hr; Static bioassayWater flea Daphnia: LC50 > 100 ppm; 96 Hr; Static bioassayIf released to soil, EDTA is expected to complex with trace metals and alkaline earth metals present in the soil, thereby causing an increase in the total solubility of the metals. EDTA may eventually predominate as the Fe(III) chelate in acidic soils and as the Ca chelate in alkaline soils. Biodegradation of EDTA in aerobic soils is the dominant
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 60-00-4: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 60-00-4: 2
Canada
CAS# 60-00-4 is listed on Canadas DSL List.
CAS# 60-00-4 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 60-00-4 is listed on the TSCA inventory.
