Name:
Ethylenediaminetetraacetic acid tetrasodium salt DNase RNase and
Synonym:
Tetrasodium ethylenediaminetetraacetate; Calsol; Celon E; Versene; Tetrine; Sodium edetate; Edetate sodium; EDTA tetrasodium
CAS:
64-02-8
Section 1 - Chemical Product
MSDS Name:Ethylenediaminetetraacetic acid tetrasodium salt DNase RNase and
Synonym:Tetrasodium ethylenediaminetetraacetate; Calsol; Celon E; Versene; Tetrine; Sodium edetate; Edetate sodium; EDTA tetrasodium
Synonym:Tetrasodium ethylenediaminetetraacetate; Calsol; Celon E; Versene; Tetrine; Sodium edetate; Edetate sodium; EDTA tetrasodium
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 64-02-8 | Nitrilotriacetic acid (NTA) | <0.1 | 205-355-7 |
| Hazard Symbols: XI Risk Phrases: 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Not available.
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid breathing dust.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Aqueous solutions cannot be stored in aluminum, carbon steel, copper, copper alloys, zinc or nickel containers.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid breathing dust.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Aqueous solutions cannot be stored in aluminum, carbon steel, copper, copper alloys, zinc or nickel containers.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 64-02-8: CAS# 139-13-9: CAS# 10378-23-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 64-02-8: CAS# 139-13-9: CAS# 10378-23-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Powder
Color: white
Odor: none reported
pH: 10.7-11.7 (5% soln)
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not applicable.
Freezing/Melting Point: > 300 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 400 deg C
Solubility in water: Soluble.
Specific Gravity/Density: Not available.
Molecular Formula: C10H12N2O8Na4
Molecular Weight: 380.17
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation, Corrosive to aluminum in aqueous solution..
Incompatibilities with Other Materials:
Metals, strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia.
Hazardous Polymerization: Will not occur.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Dust generation, Corrosive to aluminum in aqueous solution..
Incompatibilities with Other Materials:
Metals, strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 64-02-8: AH5075000 CAS# 139-13-9: AJ0175000 CAS# 10378-23-1 unlisted.
LD50/LC50:
CAS# 64-02-8: Draize test, rabbit, eye: 1900 ug; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Moderate.
CAS# 139-13-9: Oral, mouse: LD50 = 3160 mg/kg; Oral, rat: LD50 = 1100 mg/kg.
CAS# 10378-23-1.
Carcinogenicity:
Tetrasodium EDTA anhydrous - Not listed by ACGIH, IARC, or NTP.
Nitrilotriacetic acid (NTA) - California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2B carcinogen Tetrasodium ethylenediaminetetraacetate dihydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 64-02-8: AH5075000 CAS# 139-13-9: AJ0175000 CAS# 10378-23-1 unlisted.
LD50/LC50:
CAS# 64-02-8: Draize test, rabbit, eye: 1900 ug; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/24H Moderate.
CAS# 139-13-9: Oral, mouse: LD50 = 3160 mg/kg; Oral, rat: LD50 = 1100 mg/kg.
CAS# 10378-23-1.
Carcinogenicity:
Tetrasodium EDTA anhydrous - Not listed by ACGIH, IARC, or NTP.
Nitrilotriacetic acid (NTA) - California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2B carcinogen Tetrasodium ethylenediaminetetraacetate dihydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Catfish (tap water) 129 ppm/96H.
Catfish (tap water) 129 ppm/96H.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 64-02-8: 2
CAS# 139-13-9: 2
CAS# 10378-23-1: No information available.
Canada
CAS# 64-02-8 is listed on Canadas DSL List.
CAS# 139-13-9 is listed on Canadas DSL List.
CAS# 64-02-8 is not listed on Canadas Ingredient Disclosure List.
CAS# 139-13-9 is listed on Canadas Ingredient Disclosure List.
CAS# 10378-23-1 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 64-02-8 is listed on the TSCA inventory.
CAS# 139-13-9 is listed on the TSCA inventory.
CAS# 10378-23-1 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
