Name:
Formic acid-d2 99+ atom % D (95% in D2O)
Synonym:
Methanoic acid; Hydrogen carboxylic acid; Aminic acid; Formylic acid
CAS:
64-18-6
Section 1 - Chemical Product
MSDS Name:Formic acid-d2 99+ atom % D (95% in D2O)
Synonym:Methanoic acid; Hydrogen carboxylic acid; Aminic acid; Formylic acid
Synonym:Methanoic acid; Hydrogen carboxylic acid; Aminic acid; Formylic acid
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 64-18-6 | Formic acid-d2 | 95 | 213-057-3 |
| Hazard Symbols: C Risk Phrases: 35 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes severe burns.
Potential Health Effects
Eye:
Contact with liquid is corrosive to the eyes and causes severe burns. Lachrymator (substance which increases the flow of tears).
May cause corneal edema, ulceration, and scarring.
Skin:
Causes skin burns. The severity of injury depends on the concentration of the solution and the duration of exposure.
Ingestion:
Causes severe digestive tract burns with abdominal pain, vomiting, and possible death.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Chronic absorption of formic acid may cause damage to the kidneys, which is indicated by albuminuria and hematuria. Chronic skin contact may cause sensitization dermatitis, particularly in workers previously sensitized to formaldehyde.
Causes severe burns.
Potential Health Effects
Eye:
Contact with liquid is corrosive to the eyes and causes severe burns. Lachrymator (substance which increases the flow of tears).
May cause corneal edema, ulceration, and scarring.
Skin:
Causes skin burns. The severity of injury depends on the concentration of the solution and the duration of exposure.
Ingestion:
Causes severe digestive tract burns with abdominal pain, vomiting, and possible death.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Chronic absorption of formic acid may cause damage to the kidneys, which is indicated by albuminuria and hematuria. Chronic skin contact may cause sensitization dermatitis, particularly in workers previously sensitized to formaldehyde.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Hemodialysis should be considered in severe intoxication. Persons with chronic respiratory, skin, kidney, or liver diseases or eye disorders may be at increased risk from exposure to this product.
Antidote: Folic acid may be of benefit by hastening the metabolism of formic acid to carbon dioxide.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do NOT induce vomiting. Get medical aid immediately.
If victim is fully conscious, give a cupful of water. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Hemodialysis should be considered in severe intoxication. Persons with chronic respiratory, skin, kidney, or liver diseases or eye disorders may be at increased risk from exposure to this product.
Antidote: Folic acid may be of benefit by hastening the metabolism of formic acid to carbon dioxide.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water fog, dry chemical, carbon dioxide, or regular foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Contact with metals may evolve flammable hydrogen gas. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water fog, dry chemical, carbon dioxide, or regular foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Large spills may be neutralized with dilute alkaline solutions of soda ash (sodium carbonate, Na2CO3), or lime (calcium oxide, CaO). Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Approach spill from upwind.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Large spills may be neutralized with dilute alkaline solutions of soda ash (sodium carbonate, Na2CO3), or lime (calcium oxide, CaO). Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Approach spill from upwind.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. emsdss may develop pressure upon prolonged storage. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat and flame. Do not breathe vapor or mist.
Storage:
Keep refrigerated. (Store below 4C/39F.) Keep from contact with oxidizing materials. Corrosives area. Do not store in metal containers. Do not store near alkaline substances. Vent periodically. Glacial formic acid will slowly decompose to carbon monoxide at room temperature resulting in increased pressure if containers are sealed or unvented.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. emsdss may develop pressure upon prolonged storage. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat and flame. Do not breathe vapor or mist.
Storage:
Keep refrigerated. (Store below 4C/39F.) Keep from contact with oxidizing materials. Corrosives area. Do not store in metal containers. Do not store near alkaline substances. Vent periodically. Glacial formic acid will slowly decompose to carbon monoxide at room temperature resulting in increased pressure if containers are sealed or unvented.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 64-18-6: United Kingdom, WEL - TWA: 5 ppm TWA; 9.6 mg/m3 TWA United Kingdom, WEL - STEL: 15 ppm STEL; 28.8 mg/m3 STEL United States OSHA: 5 ppm TWA; 9 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 9.5 mg/m3 VLE Belgium - STEL: 10 ppm VLE; 19 mg/m3 VLE France - VLE: 5 ppm VLE; 9 mg/m3 VLE Germany: 5 ppm TWA; 9.5 mg/m3 TWA Japan: 5 ppm OEL; 9.4 mg/m3 OEL Malaysia: 5 ppm TWA; 9.4 mg/m3 TWA Netherlands: 5 ppm MAC; 9 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 5 ppm VLA-ED; 9 mg/m3 VLA-ED Spain: 10 ppm VLA-EC; 18 mg/m3 VLA-EC CAS# 920-42-3: United Kingdom, WEL - TWA: (listed as formic acid): 5 ppm TWA; 9.
mg/m3 TWA United Kingdom, WEL - STEL: (listed as formic acid): 15 ppm STEL; 28.8 mg/m3 STEL United States OSHA: 5 ppm TWA; 9 mg/m3 TWA (listed under Formic acid).
Belgium - TWA: (listed as formic acid): 5 ppm VLE; 9.5 mg/m3 VLE Belgium - STEL: (listed as formic acid): 10 ppm VLE; 19 mg/m3 VLE France - VLE: (listed as formic acid): 5 ppm VLE; 9 mg/m3 VLE Japan: (listed as formic acid): 5 ppm OEL; 9.4 mg/m3 OEL Malaysia: (listed as formic acid): 5 ppm TWA; 9.4 mg/m3 TWA Netherlands: (listed as formic acid): 5 ppm MAC; 9 mg/m3 MAC Russia: (listed as formic acid): 1 mg/m3 TWA Spain: (listed as formic acid): 5 ppm VLA-ED; 9 mg/m3 VLA-ED Spain: (listed as formic acid): 10 ppm VLA-EC; 18 mg/m3 VLA-EC CAS# 7789-20-0: Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield.
Skin:
Wear butyl rubber gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 64-18-6: United Kingdom, WEL - TWA: 5 ppm TWA; 9.6 mg/m3 TWA United Kingdom, WEL - STEL: 15 ppm STEL; 28.8 mg/m3 STEL United States OSHA: 5 ppm TWA; 9 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 9.5 mg/m3 VLE Belgium - STEL: 10 ppm VLE; 19 mg/m3 VLE France - VLE: 5 ppm VLE; 9 mg/m3 VLE Germany: 5 ppm TWA; 9.5 mg/m3 TWA Japan: 5 ppm OEL; 9.4 mg/m3 OEL Malaysia: 5 ppm TWA; 9.4 mg/m3 TWA Netherlands: 5 ppm MAC; 9 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 5 ppm VLA-ED; 9 mg/m3 VLA-ED Spain: 10 ppm VLA-EC; 18 mg/m3 VLA-EC CAS# 920-42-3: United Kingdom, WEL - TWA: (listed as formic acid): 5 ppm TWA; 9.
mg/m3 TWA United Kingdom, WEL - STEL: (listed as formic acid): 15 ppm STEL; 28.8 mg/m3 STEL United States OSHA: 5 ppm TWA; 9 mg/m3 TWA (listed under Formic acid).
Belgium - TWA: (listed as formic acid): 5 ppm VLE; 9.5 mg/m3 VLE Belgium - STEL: (listed as formic acid): 10 ppm VLE; 19 mg/m3 VLE France - VLE: (listed as formic acid): 5 ppm VLE; 9 mg/m3 VLE Japan: (listed as formic acid): 5 ppm OEL; 9.4 mg/m3 OEL Malaysia: (listed as formic acid): 5 ppm TWA; 9.4 mg/m3 TWA Netherlands: (listed as formic acid): 5 ppm MAC; 9 mg/m3 MAC Russia: (listed as formic acid): 1 mg/m3 TWA Spain: (listed as formic acid): 5 ppm VLA-ED; 9 mg/m3 VLA-ED Spain: (listed as formic acid): 10 ppm VLA-EC; 18 mg/m3 VLA-EC CAS# 7789-20-0: Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield.
Skin:
Wear butyl rubber gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless
Odor: pungent odor
pH: 2.38 (0.1M aq soln)
Vapor Pressure: 33.55 mm Hg @ 20 deg C
Viscosity: 1.607mPa @ 25 deg C
Boiling Point: 101 deg C
Freezing/Melting Point: 5.9 deg C
Autoignition Temperature: 434 deg C ( 813.20 deg F)
Flash Point: 69 deg C ( 156.20 deg F)
Explosion Limits, lower: 18 vol %
Explosion Limits, upper: 57 vol %
Decomposition Temperature: Not available.
Solubility in water: Soluble.
Specific Gravity/Density: 1.27 @ 20C
Molecular Formula: CD2O2
Molecular Weight: 48.04
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Keep refrigerated. Formic acid may decompose to carbon monoxide and water or carbon dioxide and hydrogen gas. These decomposition products develop pressure.
Conditions to Avoid:
Ignition sources, excess heat, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, aluminum, finely powdered metals, sulfuric acid, hydrogen peroxide, nitromethane, carbon steel, furfuryl alcohol.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen gas, formaldehyde.
Hazardous Polymerization: Will not occur.
Keep refrigerated. Formic acid may decompose to carbon monoxide and water or carbon dioxide and hydrogen gas. These decomposition products develop pressure.
Conditions to Avoid:
Ignition sources, excess heat, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, aluminum, finely powdered metals, sulfuric acid, hydrogen peroxide, nitromethane, carbon steel, furfuryl alcohol.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen gas, formaldehyde.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 64-18-6: LQ4900000 CAS# 920-42-3 unlisted.
CAS# 7789-20-0: ZC0230000 LD50/LC50:
CAS# 64-18-6: Draize test, rabbit, eye: 122 mg Severe; Inhalation, mouse: LC50 = 6200 mg/m3/15M; Inhalation, rat: LC50 = 15 gm/m3/15M; Oral, mouse: LD50 = 700 mg/kg; Oral, rat: LD50 = 1100 mg/kg.
CAS# 920-42-3.
CAS# 7789-20-0.
Carcinogenicity:
Formic acid - Not listed by ACGIH, IARC, or NTP.
Formic acid-d2 - Not listed by ACGIH, IARC, or NTP.
Water-d2 - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 64-18-6: LQ4900000 CAS# 920-42-3 unlisted.
CAS# 7789-20-0: ZC0230000 LD50/LC50:
CAS# 64-18-6: Draize test, rabbit, eye: 122 mg Severe; Inhalation, mouse: LC50 = 6200 mg/m3/15M; Inhalation, rat: LC50 = 15 gm/m3/15M; Oral, mouse: LD50 = 700 mg/kg; Oral, rat: LD50 = 1100 mg/kg.
CAS# 920-42-3.
CAS# 7789-20-0.
Carcinogenicity:
Formic acid - Not listed by ACGIH, IARC, or NTP.
Formic acid-d2 - Not listed by ACGIH, IARC, or NTP.
Water-d2 - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Bluegill/Sunfish: LC50 = 5000 mg/L; 24 Hr; UnspecifiedWater flea Daphnia: EC50 = 34 mg/L; 48 Hr; UnspecifiedIn natural water it has been shown to adsorb to sediment and would probably also biodegrade. Bioconcentration in aquatic organisms is not important.
In the atmosphere, formic acid would be scavenged by rain and dissolve in cloud water where it reacts with dissolved hydroxyl radicals. It also reacts in the vapor phase with hydroxyl radicals (half-life 36 days).
Fish: Bluegill/Sunfish: LC50 = 5000 mg/L; 24 Hr; UnspecifiedWater flea Daphnia: EC50 = 34 mg/L; 48 Hr; UnspecifiedIn natural water it has been shown to adsorb to sediment and would probably also biodegrade. Bioconcentration in aquatic organisms is not important.
In the atmosphere, formic acid would be scavenged by rain and dissolve in cloud water where it reacts with dissolved hydroxyl radicals. It also reacts in the vapor phase with hydroxyl radicals (half-life 36 days).
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FORMIC ACID
Hazard Class: 8
UN Number: 1779
Packing Group: II
IMO
Shipping Name: FORMIC ACID
Hazard Class: 8
UN Number: 1779
Packing Group: II
RID/ADR
Shipping Name: FORMIC ACID
Hazard Class: 8
UN Number: 1779
Packing group: II
USA RQ: CAS# 64-18-6: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 35 Causes severe burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 64-18-6: 1
CAS# 920-42-3: No information available.
CAS# 7789-20-0: No information available.
Canada
CAS# 64-18-6 is listed on Canadas DSL List.
CAS# 7789-20-0 is listed on Canadas DSL List.
CAS# 64-18-6 is listed on Canadas Ingredient Disclosure List.
CAS# 920-42-3 is not listed on Canadas Ingredient Disclosure List.
CAS# 7789-20-0 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 64-18-6 is listed on the TSCA inventory.
CAS# 920-42-3 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 7789-20-0 is listed on the TSCA inventory.
