Name:
Glycidol tech.
Synonym:
2,3-Epoxy-1-propanol; 3-Hydroxy-1,2-epoxypropane; Oxiranemethanol; 3-Hydroxypropylene oxide; Epihydrin alcohol; 2,3-Epoxypropanol; Glycidyl alcohol; Methanol, oxiranyl-
CAS:
556-52-5
Section 1 - Chemical Product
MSDS Name:Glycidol tech.
Synonym:2,3-Epoxy-1-propanol; 3-Hydroxy-1,2-epoxypropane; Oxiranemethanol; 3-Hydroxypropylene oxide; Epihydrin alcohol; 2,3-Epoxypropanol; Glycidyl alcohol; Methanol, oxiranyl-
Synonym:2,3-Epoxy-1-propanol; 3-Hydroxy-1,2-epoxypropane; Oxiranemethanol; 3-Hydroxypropylene oxide; Epihydrin alcohol; 2,3-Epoxypropanol; Glycidyl alcohol; Methanol, oxiranyl-
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 556-52-5 | Glycidol | 100 | 209-128-3 |
| Hazard Symbols: T Risk Phrases: 21/22 23 36/37/38 45 60 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful in contact with skin and if swallowed. Toxic by inhalation.
Irritating to eyes, respiratory system and skin. May cause cancer.
May impair fertility.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Causes skin irritation. Substance is rapidly absorbed through the skin. May be harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Inhalation of vapors causes irritation of the mucous membranes. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
Chronic:
May cause cancer according to animal studies. Repeated exposure may cause sensitization dermatitis. Repeated exposure may cause allergic respiratory reaction (asthma). May cause reproductive and fetal effects.
Harmful in contact with skin and if swallowed. Toxic by inhalation.
Irritating to eyes, respiratory system and skin. May cause cancer.
May impair fertility.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Causes skin irritation. Substance is rapidly absorbed through the skin. May be harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
Harmful if inhaled. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Inhalation of vapors causes irritation of the mucous membranes. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.
Chronic:
May cause cancer according to animal studies. Repeated exposure may cause sensitization dermatitis. Repeated exposure may cause allergic respiratory reaction (asthma). May cause reproductive and fetal effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Combustible liquid and vapor.
Extinguishing Media:
Do NOT use water directly on fire. Use dry chemical, carbon dioxide, or alcohol-resistant foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Combustible liquid and vapor.
Extinguishing Media:
Do NOT use water directly on fire. Use dry chemical, carbon dioxide, or alcohol-resistant foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wash area with soap and water.
Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wash area with soap and water.
Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep away from heat and flame.
Storage:
Keep away from heat and flame. Keep refrigerated. (Store below 4C/39F.) Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep away from heat and flame.
Storage:
Keep away from heat and flame. Keep refrigerated. (Store below 4C/39F.) Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 556-52-5: United States OSHA: 50 ppm TWA; 150 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 6.2 mg/m3 VLE France - VME: 25 ppm VME; 75 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Malaysia: 2 ppm TWA; 6.1 mg/m3 TWA Russia: 5 mg/m3 TWA Spain: 2 ppm VLA-ED; 6.2 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 556-52-5: United States OSHA: 50 ppm TWA; 150 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 6.2 mg/m3 VLE France - VME: 25 ppm VME; 75 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Malaysia: 2 ppm TWA; 6.1 mg/m3 TWA Russia: 5 mg/m3 TWA Spain: 2 ppm VLA-ED; 6.2 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: 0.9 mbar @ 25 C
Viscosity: Not available.
Boiling Point: 160-161 deg C @ 760 mm Hg
Freezing/Melting Point: -54 deg C
Autoignition Temperature: 415 deg C ( 779.00 deg F)
Flash Point: 71 deg C ( 159.80 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 167 deg C
Solubility in water: Soluble.
Specific Gravity/Density: 1.11 @ 20C/4C
Molecular Formula: C3H6O2
Molecular Weight: 74.08
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
May decompose on exposure to moist air or water.
Conditions to Avoid:
Ignition sources, excess heat.
Incompatibilities with Other Materials:
Metals, strong oxidizing agents, strong acids, bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported.
May decompose on exposure to moist air or water.
Conditions to Avoid:
Ignition sources, excess heat.
Incompatibilities with Other Materials:
Metals, strong oxidizing agents, strong acids, bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 556-52-5: UB4375000 LD50/LC50:
CAS# 556-52-5: Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 558 mg/3D Moderate; Draize test, rabbit, skin: 100 mg/24H Moderate; Inhalation, mouse: LC50 = 450 ppm/4H; Inhalation, rat: LC50 = 580 ppm/8H; Oral, mouse: LD50 = 431 mg/kg; Oral, rat: LD50 = 420 mg/kg; Skin, rabbit: LD50 = 1980 mg/kg.
Carcinogenicity:
Glycidol - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 7/1/90 NTP: Suspect carcinogen IARC: Group 2A carcinogen Other:
See actual entry in RTECS for complete information.
CAS# 556-52-5: UB4375000 LD50/LC50:
CAS# 556-52-5: Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 558 mg/3D Moderate; Draize test, rabbit, skin: 100 mg/24H Moderate; Inhalation, mouse: LC50 = 450 ppm/4H; Inhalation, rat: LC50 = 580 ppm/8H; Oral, mouse: LD50 = 431 mg/kg; Oral, rat: LD50 = 420 mg/kg; Skin, rabbit: LD50 = 1980 mg/kg.
Carcinogenicity:
Glycidol - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 7/1/90 NTP: Suspect carcinogen IARC: Group 2A carcinogen Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
IMO
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: III
RID/ADR
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing group: III
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 45 May cause cancer.
R 21/22 Harmful in contact with skin and if
swallowed.
R 23 Toxic by inhalation.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 60 May impair fertility.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 556-52-5: 1
Canada
CAS# 556-52-5 is listed on Canadas DSL List.
CAS# 556-52-5 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 556-52-5 is listed on the TSCA inventory.
