Name:
Guanidine Hydrochloride 99% (Contains 0.2-0.4% SiO2 as Anti-Caking
Synonym:
Guanidine Monohydrochloride; Guanidinium Chloride; Guanidinium Hydrochloride
CAS:
50-01-1
Section 1 - Chemical Product
MSDS Name:Guanidine Hydrochloride 99% (Contains 0.2-0.4% SiO2 as Anti-Caking
Synonym:Guanidine Monohydrochloride; Guanidinium Chloride; Guanidinium Hydrochloride
Synonym:Guanidine Monohydrochloride; Guanidinium Chloride; Guanidinium Hydrochloride
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 50-01-1 | GUANIDINE HYDROCHLORIDE | 99 | 200-002-3 |
| Hazard Symbols: XN Risk Phrases: 22 36/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to eyes and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause minor neurological effects.
Inhalation:
Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
Chronic:
Repeated or prolonged exposure may cause CNS stimulation.
Harmful if swallowed. Irritating to eyes and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause minor neurological effects.
Inhalation:
Dust is irritating to the respiratory tract. The toxicological properties of this substance have not been fully investigated.
Chronic:
Repeated or prolonged exposure may cause CNS stimulation.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide. Use agent most appropriate to extinguish fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide. Use agent most appropriate to extinguish fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section).
Avoid generating dusty conditions. Carefully scoop up and place into appropriate disposal container. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.
Spills/Leaks:
Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section).
Avoid generating dusty conditions. Carefully scoop up and place into appropriate disposal container. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 50-01-1: Netherlands: (listed as rubber solvent (naphtha)): 400 ppm MAC; 1 mg/m3 MAC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 50-01-1: Netherlands: (listed as rubber solvent (naphtha)): 400 ppm MAC; 1 mg/m3 MAC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystalline powder
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 182.50 - 185.50 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.354
Molecular Formula: CH5N3.HCl
Molecular Weight: 95.53
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable. However, may decompose if heated.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, temperatures above 130C.
Incompatibilities with Other Materials:
Strong oxidizing agents, moisture.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable. However, may decompose if heated.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, temperatures above 130C.
Incompatibilities with Other Materials:
Strong oxidizing agents, moisture.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 50-01-1: MF4300000 LD50/LC50:
CAS# 50-01-1: Draize test, rabbit, eye: 81400 ug Moderate; Draize test, rabbit, skin: 500 mg/24H Severe; Oral, mouse: LD50 = 571 mg/kg; Oral, rat: LD50 = 475 mg/kg.
Carcinogenicity:
GUANIDINE HYDROCHLORIDE - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 50-01-1: MF4300000 LD50/LC50:
CAS# 50-01-1: Draize test, rabbit, eye: 81400 ug Moderate; Draize test, rabbit, skin: 500 mg/24H Severe; Oral, mouse: LD50 = 571 mg/kg; Oral, rat: LD50 = 475 mg/kg.
Carcinogenicity:
GUANIDINE HYDROCHLORIDE - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 36/38 Irritating to eyes and skin.
Safety Phrases:
S 22 Do not breathe dust.
WGK (Water Danger/Protection)
CAS# 50-01-1: 1
Canada
CAS# 50-01-1 is listed on Canadas DSL List.
CAS# 50-01-1 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 50-01-1 is listed on the TSCA inventory.
