Name:
Hexadecyltrimethylammonium bromide
Synonym:
Cetrimide; Cetrimonium bromide; Palmityltrimethylammonium bromide; N,N,N-Trimethyl-1-hexadecanaminium bromide; Cetyltrimethylammonium bromide
CAS:
57-09-0
Section 1 - Chemical Product
MSDS Name:Hexadecyltrimethylammonium bromide
Synonym:Cetrimide; Cetrimonium bromide; Palmityltrimethylammonium bromide; N,N,N-Trimethyl-1-hexadecanaminium bromide; Cetyltrimethylammonium bromide
Synonym:Cetrimide; Cetrimonium bromide; Palmityltrimethylammonium bromide; N,N,N-Trimethyl-1-hexadecanaminium bromide; Cetyltrimethylammonium bromide
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 57-09-0 | Hexadecyltrimethylammonium bromide | >99 | 200-311-3 |
| Hazard Symbols: XN Risk Phrases: 22 37 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to respiratory system.
Potential Health Effects
Eye:
May cause severe eye irritation. May result in corneal injury.
Skin:
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be absorbed through the skin. May cause severe irritation and possible burns.
Ingestion:
Harmful if swallowed. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
Inhalation:
Causes respiratory tract irritation. May cause burns to the respiratory tract. May cause cardiac abnormalities. May cause Central Nervous System Effects characterized by apathy, mental confusion, blurred vision, and tremors.
Chronic:
Repeated exposure may cause sensitization dermatitis.
Harmful if swallowed. Irritating to respiratory system.
Potential Health Effects
Eye:
May cause severe eye irritation. May result in corneal injury.
Skin:
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be absorbed through the skin. May cause severe irritation and possible burns.
Ingestion:
Harmful if swallowed. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
Inhalation:
Causes respiratory tract irritation. May cause burns to the respiratory tract. May cause cardiac abnormalities. May cause Central Nervous System Effects characterized by apathy, mental confusion, blurred vision, and tremors.
Chronic:
Repeated exposure may cause sensitization dermatitis.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Carefully scoop up and place into appropriate disposal container. Provide ventilation.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Carefully scoop up and place into appropriate disposal container. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get on skin or in eyes. Do not ingest or inhale.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get on skin or in eyes. Do not ingest or inhale.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 57-09-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Nitrile or Neoprene gloves are recommended.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 57-09-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Nitrile or Neoprene gloves are recommended.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: white
Odor: none reported
pH: Not available.
Vapor Pressure: Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 470 deg F
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 470 F
Solubility in water: 10% in water.
Specific Gravity/Density: Not available.
Molecular Formula: C19H42BrN
Molecular Weight: 364.2047
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable. However, may decompose if heated.
Conditions to Avoid:
Incompatible materials, dust generation, temperatures above 150C.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Stable. However, may decompose if heated.
Conditions to Avoid:
Incompatible materials, dust generation, temperatures above 150C.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 57-09-0: BQ7875000 LD50/LC50:
CAS# 57-09-0: Draize test, rabbit, eye: 450 mg Severe; Oral, rat: LD50 = 410 mg/kg.
Carcinogenicity:
Hexadecyltrimethylammonium bromide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 57-09-0: BQ7875000 LD50/LC50:
CAS# 57-09-0: Draize test, rabbit, eye: 450 mg Severe; Oral, rat: LD50 = 410 mg/kg.
Carcinogenicity:
Hexadecyltrimethylammonium bromide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 37 Irritating to respiratory system.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 57-09-0: 3
Canada
CAS# 57-09-0 is listed on Canadas DSL List.
CAS# 57-09-0 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 57-09-0 is listed on the TSCA inventory.
