Name:
Hydrazine anhydrous
Synonym:
Diamine; Diamide
CAS:
302-01-2
Section 1 - Chemical Product
MSDS Name:Hydrazine anhydrous
Synonym:Diamine; Diamide
Synonym:Diamine; Diamide
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 302-01-2 | Hydrazine | >95 | 206-114-9 |
| Hazard Symbols: T C N Risk Phrases: 10 23/24/25 34 43 45 50/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Toxic by inhalation, in contact with skin and if swallowed. Causes burns. May cause sensitization by skin contact.
May cause cancer. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Cancer suspect agent.
Potential Health Effects
Eye:
May cause irreversible eye injury. Exposure to the vapors or liquid may cause temporary blindness. Causes severe eye irritation and burns.
Skin:
May be fatal if absorbed through the skin. Prolonged and/or repeated contact may cause irritation and/or dermatitis. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Contact with liquid is corrosive and causes severe burns and ulceration. Contact with the skin may dissolve hair.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage.
Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma. Exposure may cause anemia and other blood abnormalities.
Inhalation:
Harmful if inhaled. Irritation may lead to chemical pneumonitis and pulmonary edema. May cause liver and kidney damage. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. Vapors may cause dizziness, nausea, itching, burning, and swelling of the eyes.
Chronic:
Repeated inhalation may cause chronic bronchitis. May cause cancer according to animal studies. Repeated exposure may cause sensitization dermatitis. May cause reproductive and fetal effects.
Flammable. Toxic by inhalation, in contact with skin and if swallowed. Causes burns. May cause sensitization by skin contact.
May cause cancer. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Cancer suspect agent.
Potential Health Effects
Eye:
May cause irreversible eye injury. Exposure to the vapors or liquid may cause temporary blindness. Causes severe eye irritation and burns.
Skin:
May be fatal if absorbed through the skin. Prolonged and/or repeated contact may cause irritation and/or dermatitis. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Contact with liquid is corrosive and causes severe burns and ulceration. Contact with the skin may dissolve hair.
Ingestion:
Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage.
Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma. Exposure may cause anemia and other blood abnormalities.
Inhalation:
Harmful if inhaled. Irritation may lead to chemical pneumonitis and pulmonary edema. May cause liver and kidney damage. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. Vapors may cause dizziness, nausea, itching, burning, and swelling of the eyes.
Chronic:
Repeated inhalation may cause chronic bronchitis. May cause cancer according to animal studies. Repeated exposure may cause sensitization dermatitis. May cause reproductive and fetal effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Autoignition temperature varies based upon contact surface. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May be ignited by heat, sparks, and flame. Vapors may form an explosive mixture with air.
Containers may explode when heated.
Extinguishing Media:
For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Autoignition temperature varies based upon contact surface. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. May be ignited by heat, sparks, and flame. Vapors may form an explosive mixture with air.
Containers may explode when heated.
Extinguishing Media:
For large fires, use water spray, fog, or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Do not get water inside containers. Approach spill from upwind. Use water spray to cool and disperse vapors, protect personnel, and dilute spills to form nonflammable mixtures. Control runoff and isolate discharged material for proper disposal.
Spills/Leaks:
Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Do not get water inside containers. Approach spill from upwind. Use water spray to cool and disperse vapors, protect personnel, and dilute spills to form nonflammable mixtures. Control runoff and isolate discharged material for proper disposal.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep away from heat, sparks and flame.
Use only with adequate ventilation or respiratory protection.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Storage under a nitrogen blanket has been recommended. Isolate from oxidizing materials and acids.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep away from heat, sparks and flame.
Use only with adequate ventilation or respiratory protection.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Storage under a nitrogen blanket has been recommended. Isolate from oxidizing materials and acids.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 302-01-2: United Kingdom, WEL - TWA: 0.02 ppm TWA; 0.03 mg/m3 TWA United Kingdom, WEL - STEL: 0.1 ppm STEL; 0.13 mg/m3 STEL United States OSHA: 1 ppm TWA; 1.3 mg/m3 TWA Belgium - TWA: 0.01 ppm VLE; 0.013 mg/m3 VLE France - VME: 0.1 ppm VME; 0.1 mg/m3 VME Germany: 0.1 ppm TWA; 0.13 mg/m3 TWA Germany: Skin absorber Japan: 0.1 ppm OEL; 0.13 mg/m3 OEL Malaysia: 0.01 ppm TWA; 0.013 mg/m3 TWA Russia: 0.1 mg/m3 TWA Spain: 0.01 ppm VLA-ED; 0.013 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 302-01-2: United Kingdom, WEL - TWA: 0.02 ppm TWA; 0.03 mg/m3 TWA United Kingdom, WEL - STEL: 0.1 ppm STEL; 0.13 mg/m3 STEL United States OSHA: 1 ppm TWA; 1.3 mg/m3 TWA Belgium - TWA: 0.01 ppm VLE; 0.013 mg/m3 VLE France - VME: 0.1 ppm VME; 0.1 mg/m3 VME Germany: 0.1 ppm TWA; 0.13 mg/m3 TWA Germany: Skin absorber Japan: 0.1 ppm OEL; 0.13 mg/m3 OEL Malaysia: 0.01 ppm TWA; 0.013 mg/m3 TWA Russia: 0.1 mg/m3 TWA Spain: 0.01 ppm VLA-ED; 0.013 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: strong odor - ammonia-like
pH: Not available.
Vapor Pressure: 10 mm Hg @ 20 deg C
Viscosity: 0.90
Boiling Point: 113 deg C
Freezing/Melting Point: 1.4 deg C
Autoignition Temperature: 270 deg C ( 518.00 deg F)
Flash Point: 38 deg C ( 100.40 deg F)
Explosion Limits, lower: 2.9%
Explosion Limits, upper: 98%
Decomposition Temperature: Not available.
Solubility in water: Soluble.
Specific Gravity/Density: 1.01 (water=1)
Molecular Formula: N2H4
Molecular Weight: 32.05
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Thermally unstable.
Conditions to Avoid:
Light, ignition sources, moisture, temperatures above 150C.
Incompatibilities with Other Materials:
Substance is highly reactive reducing agent. Incompatible with oxidizing agents (including air), acids, and some metal oxides and metals. Substance may spontaneously ignite in air when in contact with porous materials. Ignites on contact with dinitrogen oxide and tetroxide, hydrogen peroxide, tetryl, and nitric acid. Explodes on contact with dicyanofurazan, n-halomides, potassium, silver compounds, sodium hydroxide, titanium compounds, and trioxygen difluoride. Explosive compounds may result from contact with air, chloromethylnitrobenzene, lithium perchlorate, metal salts, methanol + nitromethane, sodium , and sodium perchlorate. Also incompatible with barium oxide or calcium oxide, benzeneseleninic acid or anhydride, calcium, carbon dioxide + stainless steel, 1-chloro-2,4-dinitrobenzene, cotton waste + heavy metals, (difluoroamino)difluoroacetonitrile, iodine pentoxide, rust, ruthenium(III) oxide, thiocarbonyl azide thiocyanate, Hazardous Decomposition Products:
Oxides of nitrogen, ammonia and/or derivatives.
Hazardous Polymerization: Has not been reported.
Thermally unstable.
Conditions to Avoid:
Light, ignition sources, moisture, temperatures above 150C.
Incompatibilities with Other Materials:
Substance is highly reactive reducing agent. Incompatible with oxidizing agents (including air), acids, and some metal oxides and metals. Substance may spontaneously ignite in air when in contact with porous materials. Ignites on contact with dinitrogen oxide and tetroxide, hydrogen peroxide, tetryl, and nitric acid. Explodes on contact with dicyanofurazan, n-halomides, potassium, silver compounds, sodium hydroxide, titanium compounds, and trioxygen difluoride. Explosive compounds may result from contact with air, chloromethylnitrobenzene, lithium perchlorate, metal salts, methanol + nitromethane, sodium , and sodium perchlorate. Also incompatible with barium oxide or calcium oxide, benzeneseleninic acid or anhydride, calcium, carbon dioxide + stainless steel, 1-chloro-2,4-dinitrobenzene, cotton waste + heavy metals, (difluoroamino)difluoroacetonitrile, iodine pentoxide, rust, ruthenium(III) oxide, thiocarbonyl azide thiocyanate, Hazardous Decomposition Products:
Oxides of nitrogen, ammonia and/or derivatives.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 302-01-2: MU7175000 LD50/LC50:
CAS# 302-01-2: Dermal, guinea pig: LD50 = 190 mg/kg; Inhalation, mouse: LC50 = 252 ppm/4H; Inhalation, mouse: LC50 = 1000 mg/m3/2H; Inhalation, mouse: LC50 = 320 mg/m3/4H; Inhalation, rat: LC50 = 570 ppm/4H; Inhalation, rat: LC50 = 130 mg/m3/2H; Oral, mouse: LD50 = 59 mg/kg; Oral, mouse: LD50 = 59 mg/kg; Oral, rat: LD50 = 60 mg/kg; Oral, rat: LD50 = 60 mg/kg; Skin, rabbit: LD50 = 91 mg/kg.
Carcinogenicity:
Hydrazine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2B carcinogen Other:
See actual entry in RTECS for complete information.
CAS# 302-01-2: MU7175000 LD50/LC50:
CAS# 302-01-2: Dermal, guinea pig: LD50 = 190 mg/kg; Inhalation, mouse: LC50 = 252 ppm/4H; Inhalation, mouse: LC50 = 1000 mg/m3/2H; Inhalation, mouse: LC50 = 320 mg/m3/4H; Inhalation, rat: LC50 = 570 ppm/4H; Inhalation, rat: LC50 = 130 mg/m3/2H; Oral, mouse: LD50 = 59 mg/kg; Oral, mouse: LD50 = 59 mg/kg; Oral, rat: LD50 = 60 mg/kg; Oral, rat: LD50 = 60 mg/kg; Skin, rabbit: LD50 = 91 mg/kg.
Carcinogenicity:
Hydrazine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2B carcinogen Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Rainbow trout (fresh water) 146ppm/0.5H (Lethal) Guppy (hard water): LC50 = 3.85mg/L/96H Guppy (soft water): LC50 = 0.61mg/L/96H Bluegill sunfish: LC50 = 1.08mg/L/96H
Rainbow trout (fresh water) 146ppm/0.5H (Lethal) Guppy (hard water): LC50 = 3.85mg/L/96H Guppy (soft water): LC50 = 0.61mg/L/96H Bluegill sunfish: LC50 = 1.08mg/L/96H
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 302-01-2: 1 lb final RQ; 0.454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T C N
Risk Phrases:
R 45 May cause cancer.
R 10 Flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 34 Causes burns.
R 43 May cause sensitization by skin contact.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 302-01-2: 3
Canada
CAS# 302-01-2 is listed on Canadas DSL List.
CAS# 302-01-2 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 302-01-2 is listed on the TSCA inventory.
