Name:
Hydrazine hydrate 100% (Hydrazine 64%)
Synonym:
None
CAS:
302-01-2
Section 1 - Chemical Product
MSDS Name:Hydrazine hydrate 100% (Hydrazine 64%)
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 302-01-2 | Hydrazine | 64 | 206-114-9 |
| Hazard Symbols: T C N Risk Phrases: 23/24/25 34 43 45 50/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Causes burns. May cause sensitization by skin contact. May cause cancer.
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Corrosive.Air sensitive.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye burns. Effects may be delayed. May cause temporary blindness. May cause visual impairment.
Skin:
Causes skin burns. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Toxic in contact with skin. Substance is readily absorbed through the skin.
Ingestion:
Poison by ingestion. May cause liver and kidney damage. Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma. Exposure may cause anemia and other blood abnormalities.
Inhalation:
Effects may be delayed. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). May cause liver and kidney damage. Causes chemical burns to the respiratory tract. May cause lung damage. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Toxic if inhaled. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. May cause respiratory sensitization.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated exposure may cause adverse reproductive effects. Repeated inhalation may cause chronic bronchitis. May cause fetal effects. Repeated exposure may cause sensitization dermatitis.
Toxic by inhalation, in contact with skin and if swallowed. Causes burns. May cause sensitization by skin contact. May cause cancer.
Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Corrosive.Air sensitive.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye burns. Effects may be delayed. May cause temporary blindness. May cause visual impairment.
Skin:
Causes skin burns. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Toxic in contact with skin. Substance is readily absorbed through the skin.
Ingestion:
Poison by ingestion. May cause liver and kidney damage. Causes digestive tract burns with immediate pain, swelling of the throat, convulsions, and possible coma. Exposure may cause anemia and other blood abnormalities.
Inhalation:
Effects may be delayed. May cause cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). May cause liver and kidney damage. Causes chemical burns to the respiratory tract. May cause lung damage. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Toxic if inhaled. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. May cause respiratory sensitization.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
Prolonged or repeated exposure may cause adverse reproductive effects. Repeated inhalation may cause chronic bronchitis. May cause fetal effects. Repeated exposure may cause sensitization dermatitis.
Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Antidote: None reported.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Antidote: None reported.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Combustible liquid. Containers may explode when heated.
Powerful reducing agent.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Combustible liquid. Containers may explode when heated.
Powerful reducing agent.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool. Provide ventilation. Place under an inert atmosphere.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool. Provide ventilation. Place under an inert atmosphere.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Handle under an inert atmosphere. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Use only with adequate ventilation.
Storage:
Keep away from sources of ignition. Do not store in direct sunlight.
Keep refrigerated. (Store below 4C/39F.) Store in a tightly closed container. Corrosives area. Do not expose to air. Store under an inert atmosphere.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Handle under an inert atmosphere. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Use only with adequate ventilation.
Storage:
Keep away from sources of ignition. Do not store in direct sunlight.
Keep refrigerated. (Store below 4C/39F.) Store in a tightly closed container. Corrosives area. Do not expose to air. Store under an inert atmosphere.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Use only under a chemical fume hood.
Exposure Limits CAS# 302-01-2: United Kingdom, WEL - TWA: 0.02 ppm TWA; 0.03 mg/m3 TWA United Kingdom, WEL - STEL: 0.1 ppm STEL; 0.13 mg/m3 STEL United States OSHA: 1 ppm TWA; 1.3 mg/m3 TWA Belgium - TWA: 0.01 ppm VLE; 0.013 mg/m3 VLE France - VME: 0.1 ppm VME; 0.1 mg/m3 VME Germany: 0.1 ppm TWA; 0.13 mg/m3 TWA Germany: Skin absorber Japan: 0.1 ppm OEL; 0.13 mg/m3 OEL Malaysia: 0.01 ppm TWA; 0.013 mg/m3 TWA Russia: 0.1 mg/m3 TWA Spain: 0.01 ppm VLA-ED; 0.013 mg/m3 VLA-ED CAS# 7732-18-5: CAS# 7803-57-8: Japan: 0.21 mg/m3 OEL CAS# 10217-52-4: Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Use only under a chemical fume hood.
Exposure Limits CAS# 302-01-2: United Kingdom, WEL - TWA: 0.02 ppm TWA; 0.03 mg/m3 TWA United Kingdom, WEL - STEL: 0.1 ppm STEL; 0.13 mg/m3 STEL United States OSHA: 1 ppm TWA; 1.3 mg/m3 TWA Belgium - TWA: 0.01 ppm VLE; 0.013 mg/m3 VLE France - VME: 0.1 ppm VME; 0.1 mg/m3 VME Germany: 0.1 ppm TWA; 0.13 mg/m3 TWA Germany: Skin absorber Japan: 0.1 ppm OEL; 0.13 mg/m3 OEL Malaysia: 0.01 ppm TWA; 0.013 mg/m3 TWA Russia: 0.1 mg/m3 TWA Spain: 0.01 ppm VLA-ED; 0.013 mg/m3 VLA-ED CAS# 7732-18-5: CAS# 7803-57-8: Japan: 0.21 mg/m3 OEL CAS# 10217-52-4: Personal Protective Equipment Eyes: Wear chemical splash goggles and face shield.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: strong odor - ammonia-like
pH: Strong Base
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 118 deg C
Freezing/Melting Point: -51.7 deg C
Autoignition Temperature: Not available.
Flash Point: 75 deg C ( 167.00 deg F)
Explosion Limits, lower: 3.5%
Explosion Limits, upper: 99.99%
Decomposition Temperature: Not available.
Solubility in water: Miscible in water.
Specific Gravity/Density: Not available.
Molecular Formula: H4N2.H2O
Molecular Weight: 50.06
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable. However becomes unstable if dehydrated.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess heat, temperatures above 100C.
Incompatibilities with Other Materials:
Oxidizing agents, acids, alkali metals, copper, glass, halogens, iron, nitric acid, nitrites, perchlorates, sodium hydroxide, zinc, potassium, hydrogen peroxide, sodium, lead, dinitrogen tetraoxide, molybdenum(IV) oxide, mercuric oxide, organic matter, metal salts, stannous chloride, 2,4-Dinitrochlorobenzene, thiocyanates, rust, metal oxides.
Hazardous Decomposition Products:
Nitrogen oxides, ammonia and/or derivatives, hydrogen gas.
Hazardous Polymerization: Has not been reported.
Stable. However becomes unstable if dehydrated.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess heat, temperatures above 100C.
Incompatibilities with Other Materials:
Oxidizing agents, acids, alkali metals, copper, glass, halogens, iron, nitric acid, nitrites, perchlorates, sodium hydroxide, zinc, potassium, hydrogen peroxide, sodium, lead, dinitrogen tetraoxide, molybdenum(IV) oxide, mercuric oxide, organic matter, metal salts, stannous chloride, 2,4-Dinitrochlorobenzene, thiocyanates, rust, metal oxides.
Hazardous Decomposition Products:
Nitrogen oxides, ammonia and/or derivatives, hydrogen gas.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 302-01-2: MU7175000 CAS# 7732-18-5: ZC0110000 CAS# 7803-57-8: MV8050000 CAS# 10217-52-4: MV4590000 LD50/LC50:
CAS# 302-01-2: Dermal, guinea pig: LD50 = 190 mg/kg; Inhalation, mouse: LC50 = 252 ppm/4H; Inhalation, mouse: LC50 = 1000 mg/m3/2H; Inhalation, mouse: LC50 = 320 mg/m3/4H; Inhalation, rat: LC50 = 570 ppm/4H; Inhalation, rat: LC50 = 130 mg/m3/2H; Oral, mouse: LD50 = 59 mg/kg; Oral, mouse: LD50 = 59 mg/kg; Oral, rat: LD50 = 60 mg/kg; Oral, rat: LD50 = 60 mg/kg; Skin, rabbit: LD50 = 91 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 7803-57-8: Oral, mouse: LD50 = 83 mg/kg; Oral, rabbit: LD50 = 55 mg/kg; Oral, rat: LD50 = 129 mg/kg.
CAS# 10217-52-4: Inhalation, rat: LC50 = 80 mg/m3; Oral, mouse: LD50 = 83 mg/kg; Oral, rabbit: LD50 = 55 mg/kg; Oral, rat: LD50 = 129 mg/kg.
Carcinogenicity:
Hydrazine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2B carcinogen Water - Not listed by ACGIH, IARC, or NTP.
Hydrazine monohydrate - Not listed by ACGIH, IARC, or NTP.
Hydrazine hydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 302-01-2: MU7175000 CAS# 7732-18-5: ZC0110000 CAS# 7803-57-8: MV8050000 CAS# 10217-52-4: MV4590000 LD50/LC50:
CAS# 302-01-2: Dermal, guinea pig: LD50 = 190 mg/kg; Inhalation, mouse: LC50 = 252 ppm/4H; Inhalation, mouse: LC50 = 1000 mg/m3/2H; Inhalation, mouse: LC50 = 320 mg/m3/4H; Inhalation, rat: LC50 = 570 ppm/4H; Inhalation, rat: LC50 = 130 mg/m3/2H; Oral, mouse: LD50 = 59 mg/kg; Oral, mouse: LD50 = 59 mg/kg; Oral, rat: LD50 = 60 mg/kg; Oral, rat: LD50 = 60 mg/kg; Skin, rabbit: LD50 = 91 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
CAS# 7803-57-8: Oral, mouse: LD50 = 83 mg/kg; Oral, rabbit: LD50 = 55 mg/kg; Oral, rat: LD50 = 129 mg/kg.
CAS# 10217-52-4: Inhalation, rat: LC50 = 80 mg/m3; Oral, mouse: LD50 = 83 mg/kg; Oral, rabbit: LD50 = 55 mg/kg; Oral, rat: LD50 = 129 mg/kg.
Carcinogenicity:
Hydrazine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2B carcinogen Water - Not listed by ACGIH, IARC, or NTP.
Hydrazine monohydrate - Not listed by ACGIH, IARC, or NTP.
Hydrazine hydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
European carp: LC50 = 1.48mg/L (unknown time) Zebra fish: LC50 = 3.18mg/L (unknown time) Roach: LC50 = 0.85mg/L (unknown time)
European carp: LC50 = 1.48mg/L (unknown time) Zebra fish: LC50 = 3.18mg/L (unknown time) Roach: LC50 = 0.85mg/L (unknown time)
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: HYDRAZINE, AQUEOUS SOLUTION
Hazard Class: 8 (6.1)
UN Number: 2030
Packing Group: II
IMO
Shipping Name: HYDRAZINE, AQUEOUS SOLUTION
Hazard Class: 8 (6.1)
UN Number: 2030
Packing Group: II
RID/ADR
Shipping Name: HYDRAZINE, AQUEOUS SOLUTION
Hazard Class: 8
UN Number: 2030
Packing group: II
USA RQ: CAS# 302-01-2: 1 lb final RQ; 0.454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T C N
Risk Phrases:
R 45 May cause cancer.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 34 Causes burns.
R 43 May cause sensitization by skin contact.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 302-01-2: 3
CAS# 7732-18-5: No information available.
CAS# 7803-57-8: 3
CAS# 10217-52-4: No information available.
Canada
CAS# 302-01-2 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 302-01-2 is listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 7803-57-8 is not listed on Canadas Ingredient Disclosure List.
CAS# 10217-52-4 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 302-01-2 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 7803-57-8 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
CAS# 10217-52-4 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
