Name:
Hydrofluoric Acid (Hydrogen Fluoride liquefied)
Synonym:
Fluohydric Acid, Fluoric Acid
CAS:
7664-39-3
Section 1 - Chemical Product
MSDS Name:Hydrofluoric Acid (Hydrogen Fluoride liquefied)
Synonym:Fluohydric Acid, Fluoric Acid
Synonym:Fluohydric Acid, Fluoric Acid
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 7664-39-3 | Hydrogen fluoride | 99.8 | 231-634-8 |
| Hazard Symbols: T+ C Risk Phrases: 26/27/28 35 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Causes severe burns.Corrosive.
Potential Health Effects
Eye:
Contact with liquid or vapor causes severe burns and possible irreversible eye damage. Solutions as dilute as 2% or lower may cause burns.
Skin:
May be fatal if absorbed through the skin. Causes severe burns with delayed tissue destruction. Substance is rapidly absorbed through the skin. Penetration may continue for several days. Causes severe tissue necrosis and bone destruction. Both liquid and vapor can cause severe burns, which may not be immediately painful or visible. May cause hypocalcemia and death. Solutions as dilute as 2% or lower may cause burns.
Ingestion:
Causes severe digestive tract burns with abdominal pain, vomiting, and possible death. May cause systemic toxic effects on the heart, liver, and kidneys. Ingestion of large amounts of fluoride may cause salivation, nausea, vomiting, abdominal pain, fever, labored breathing. Inorganic fluorides can be harmful. Acute exposure to fluorine compounds can lead to digestive tract burns, and abdominal pain. Contains fluoride. Human fatalities have been reported from acute poisoning.
Inhalation:
May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. May cause pulmonary edema and severe respiratory disturbances. Depletes calcium levels in the body which can lead to hypocalcemia and death.
Chronic:
Chronic inhalation and ingestion may cause chronic fluoride poisoning (fluorosis) characterized by weight loss, weakness, anemia, brittle bones, and stiff joints. Repeated inhalation may cause chronic bronchitis. Prolonged or repeated exposure may cause permanent bone structure abnormalities. Chronic exposure to fluoride compounds may cause systemic toxicity. Repeated inhalation may cause osteofluorosis and permanent respiratory damage. To the best of our knowledge, the chronic toxicity of this substance has not been fully investigated.
Very toxic by inhalation, in contact with skin and if swallowed.
Causes severe burns.Corrosive.
Potential Health Effects
Eye:
Contact with liquid or vapor causes severe burns and possible irreversible eye damage. Solutions as dilute as 2% or lower may cause burns.
Skin:
May be fatal if absorbed through the skin. Causes severe burns with delayed tissue destruction. Substance is rapidly absorbed through the skin. Penetration may continue for several days. Causes severe tissue necrosis and bone destruction. Both liquid and vapor can cause severe burns, which may not be immediately painful or visible. May cause hypocalcemia and death. Solutions as dilute as 2% or lower may cause burns.
Ingestion:
Causes severe digestive tract burns with abdominal pain, vomiting, and possible death. May cause systemic toxic effects on the heart, liver, and kidneys. Ingestion of large amounts of fluoride may cause salivation, nausea, vomiting, abdominal pain, fever, labored breathing. Inorganic fluorides can be harmful. Acute exposure to fluorine compounds can lead to digestive tract burns, and abdominal pain. Contains fluoride. Human fatalities have been reported from acute poisoning.
Inhalation:
May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. May cause pulmonary edema and severe respiratory disturbances. Depletes calcium levels in the body which can lead to hypocalcemia and death.
Chronic:
Chronic inhalation and ingestion may cause chronic fluoride poisoning (fluorosis) characterized by weight loss, weakness, anemia, brittle bones, and stiff joints. Repeated inhalation may cause chronic bronchitis. Prolonged or repeated exposure may cause permanent bone structure abnormalities. Chronic exposure to fluoride compounds may cause systemic toxicity. Repeated inhalation may cause osteofluorosis and permanent respiratory damage. To the best of our knowledge, the chronic toxicity of this substance has not been fully investigated.
Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. If a physician is not immediately available, apply one or two drops of 0.5% tetracaine hydrochloride solution followed by a second irrigation until medical attention arrives. Tetracaine hydrochloride will provide ocular anesthesia for 20 min. to an hour.
Skin:
Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes. Spills of HF should be flushed until medical attention arrives. SPEEDY ACTION IS CRITICAL! GET MEDICAL ATTENTION IMMEDIATELY. If available, after thorough washing (PREFERRED METHOD), a 2.5% calcium gluconate gel should be continuously massaged into the burned area, or the burned area should be immersed in a solution of 0.2% iced aqueous benzethonium chloride.
Immersion may also be done with 0.13% iced aqueous Benzalkonium chloride. If immersion is not practical, towels should be soaked with one of the aforementioned solutions and used as compresses for the burned area. Ideally compresses should be changed every two minutes.
It is suggested that a certain quantity of either prepared solution or the calcium gluconate be kept on hand at all times. These should be replaced annually if not previously used.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. SPEED IS ESSENTIAL.
A DOCTOR MUST BE NOTIFIED AT ONCE.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
Notes to Physician:
Due to delayed and persistent symptoms, observe patient closely for 48 hours. Prompt action is essential in all cases of contact.
Antidote: Always have calcium gluconate gel on hand. The use of infilitration therapy and intraarterial therapy for hydrofluoric acid burns resulting from concentrations greater than 20% should be made by qualified medical personnel. Calcium gluconate may be administered intravenously slowly to bind to the fluoride ion. This administration needs to be monitored under the supervision of a physician.
Skin:
Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes. Spills of HF should be flushed until medical attention arrives. SPEEDY ACTION IS CRITICAL! GET MEDICAL ATTENTION IMMEDIATELY. If available, after thorough washing (PREFERRED METHOD), a 2.5% calcium gluconate gel should be continuously massaged into the burned area, or the burned area should be immersed in a solution of 0.2% iced aqueous benzethonium chloride.
Immersion may also be done with 0.13% iced aqueous Benzalkonium chloride. If immersion is not practical, towels should be soaked with one of the aforementioned solutions and used as compresses for the burned area. Ideally compresses should be changed every two minutes.
It is suggested that a certain quantity of either prepared solution or the calcium gluconate be kept on hand at all times. These should be replaced annually if not previously used.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. SPEED IS ESSENTIAL.
A DOCTOR MUST BE NOTIFIED AT ONCE.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. SPEED IS ESSENTIAL, OBTAIN MEDICAL AID IMMEDIATELY.
Notes to Physician:
Due to delayed and persistent symptoms, observe patient closely for 48 hours. Prompt action is essential in all cases of contact.
Antidote: Always have calcium gluconate gel on hand. The use of infilitration therapy and intraarterial therapy for hydrofluoric acid burns resulting from concentrations greater than 20% should be made by qualified medical personnel. Calcium gluconate may be administered intravenously slowly to bind to the fluoride ion. This administration needs to be monitored under the supervision of a physician.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Reacts with most metals to form highly flammable hydrogen gas which can form explosive mixtures with air. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Material will react with water and may release flammable and/or toxic gas. Evolves heat when combined with water.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Reacts with most metals to form highly flammable hydrogen gas which can form explosive mixtures with air. Containers may explode in the heat of a fire. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Material will react with water and may release flammable and/or toxic gas. Evolves heat when combined with water.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section).
Neutralize spill with sodium bicarbonate. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust.
Provide ventilation. Material will fume during neutralization.
Approach from upwind position.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section).
Neutralize spill with sodium bicarbonate. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust.
Provide ventilation. Material will fume during neutralization.
Approach from upwind position.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed.
Do not allow contact with water. Use only in a chemical fume hood.
Discard contaminated shoes. Use caution when opening.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal or glass containers.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep container tightly closed.
Do not allow contact with water. Use only in a chemical fume hood.
Discard contaminated shoes. Use caution when opening.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal or glass containers.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 7664-39-3: United Kingdom, OES - TWA: 1.8 ppm TWA (as F); 1.5 mg/m3 TWA (as United Kingdom, OES - STEL: 3 ppm STEL (as F); 2.5 mg/m3 STEL (as United States OSHA: 3 ppm TWA Belgium - STEL: 3 ppm VLE; 2.6 mg/m3 VLE France - VLE: 3 ppm VLE; 2.5 mg/m3 VLE Germany: 3 ppm TWA; 2.5 mg/m3 TWA Germany: Skin absorber Japan: 3 ppm Ceiling; 2.5 mg/m3 Ceiling Malaysia: 3 ppm Ceiling (as F); 2.3 mg/m3 Ceiling (as F) Netherlands: 3.3 ppm STEL; 2.5 mg/m3 STEL (as F) Russia: 0.5 mg/m3 TWA Russia: 0.1 mg/m3 STEL Spain: 1.8 ppm VLA-ED; 1.5 mg/m3 VLA-ED Spain: 3 ppm VLA-EC; 2.5 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits CAS# 7664-39-3: United Kingdom, OES - TWA: 1.8 ppm TWA (as F); 1.5 mg/m3 TWA (as United Kingdom, OES - STEL: 3 ppm STEL (as F); 2.5 mg/m3 STEL (as United States OSHA: 3 ppm TWA Belgium - STEL: 3 ppm VLE; 2.6 mg/m3 VLE France - VLE: 3 ppm VLE; 2.5 mg/m3 VLE Germany: 3 ppm TWA; 2.5 mg/m3 TWA Germany: Skin absorber Japan: 3 ppm Ceiling; 2.5 mg/m3 Ceiling Malaysia: 3 ppm Ceiling (as F); 2.3 mg/m3 Ceiling (as F) Netherlands: 3.3 ppm STEL; 2.5 mg/m3 STEL (as F) Russia: 0.5 mg/m3 TWA Russia: 0.1 mg/m3 STEL Spain: 1.8 ppm VLA-ED; 1.5 mg/m3 VLA-ED Spain: 3 ppm VLA-EC; 2.5 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid below 19.5C
Color: colorless
Odor: penetrating odor - strong odor
pH: <1(Aq.Soln-10g/100ml
Vapor Pressure: 150pKa @ 30 deg C
Viscosity: Not available.
Boiling Point: 19.5 deg C
Freezing/Melting Point: -83 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 975kg/m3 @ 14C
Molecular Formula: HF
Molecular Weight: 20.0054
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Metals.
Incompatibilities with Other Materials:
Glass, concrete and other silicon-bearing materials will yield silicon tetrafluoride. Pressure build up from this process has been known to blow up glass containers., Carbonates, sulfides, and cyanides will yield toxic gases such as carbon dioxide, hydrogen sulfide, and hydrogen cyanide. Alkalis, some oxides, fluorine and other water-reactive materials will cause strong exothermic reactions that can be violent., Reacts with most common metals to produce hydrogen gas. Is corrosive to many materials including leather, rubber, and many organics., Substance is incompatible with over 35 specific chemicals. Please refer to the NFPA Fire Protection Guide for specifics..
Hazardous Decomposition Products:
Hydrogen fluoride gas, fluoride fumes.
Hazardous Polymerization: Has not been reported.
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Metals.
Incompatibilities with Other Materials:
Glass, concrete and other silicon-bearing materials will yield silicon tetrafluoride. Pressure build up from this process has been known to blow up glass containers., Carbonates, sulfides, and cyanides will yield toxic gases such as carbon dioxide, hydrogen sulfide, and hydrogen cyanide. Alkalis, some oxides, fluorine and other water-reactive materials will cause strong exothermic reactions that can be violent., Reacts with most common metals to produce hydrogen gas. Is corrosive to many materials including leather, rubber, and many organics., Substance is incompatible with over 35 specific chemicals. Please refer to the NFPA Fire Protection Guide for specifics..
Hazardous Decomposition Products:
Hydrogen fluoride gas, fluoride fumes.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 7664-39-3: MW7875000 LD50/LC50:
CAS# 7664-39-3: Inhalation, mouse: LC50 = 342 ppm/1H; Inhalation, mouse: LC50 = 5000 mg/m3/5M; Inhalation, mouse: LC50 = 270 mg/m3/60M; Inhalation, rat: LC50 = 1276 ppm/1H; Inhalation, rat: LC50 = 1100 mg/m3/60M.
Not available.
Carcinogenicity:
Hydrogen fluoride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 7664-39-3: MW7875000 LD50/LC50:
CAS# 7664-39-3: Inhalation, mouse: LC50 = 342 ppm/1H; Inhalation, mouse: LC50 = 5000 mg/m3/5M; Inhalation, mouse: LC50 = 270 mg/m3/60M; Inhalation, rat: LC50 = 1276 ppm/1H; Inhalation, rat: LC50 = 1100 mg/m3/60M.
Not available.
Carcinogenicity:
Hydrogen fluoride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish (fresh water) 60 ppm lethal (time period not specified).
Fish (fresh water) 60 ppm lethal (time period not specified).
Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: HYDROGEN FLUORIDE, ANHYDROUS
Hazard Class: 8
UN Number: 1052
Packing Group: II
IMO
Shipping Name: HYDROGEN FLUORIDE, ANHYDROUS
Hazard Class: 8
UN Number: 1052
Packing Group: II
RID/ADR
Shipping Name: HYDROGEN FLUORIDE, ANHYDROUS
Hazard Class: 8,6
UN Number: 1052
Packing group:
USA RQ: CAS# 7664-39-3: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ C
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 35 Causes severe burns.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 7664-39-3: 1
Canada
CAS# 7664-39-3 is listed on Canadas DSL List.
CAS# 7664-39-3 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 7664-39-3 is listed on the TSCA inventory.
