Name:
Isoamyl nitrite 97% stabilized with 0.2% anhydrous sodium carbonate
Synonym:
Isopentyl nitrite; 3-Methylbutyl nitrite; Vaporole; 3-Methylbutanol nitrite; Nitrous acid, 3-methylbutyl ester
CAS:
110-46-3
Section 1 - Chemical Product
MSDS Name:Isoamyl nitrite 97% stabilized with 0.2% anhydrous sodium carbonate
Synonym:Isopentyl nitrite; 3-Methylbutyl nitrite; Vaporole; 3-Methylbutanol nitrite; Nitrous acid, 3-methylbutyl ester
Synonym:Isopentyl nitrite; 3-Methylbutyl nitrite; Vaporole; 3-Methylbutanol nitrite; Nitrous acid, 3-methylbutyl ester
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 110-46-3 | Isoamyl nitrite | 97 | 203-770-8 |
| Hazard Symbols: XN F Risk Phrases: 11 20/22 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Harmful by inhalation and if swallowed.Light sensitive.Air sensitive.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
May cause skin irritation. May be absorbed through the skin in harmful amounts. May cause allergic contact dermatitis.
Ingestion:
Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed. This product contains nitrite which may cause methemoglobinemia.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation.
Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. This product contains nitrite which may cause methemoglobinemia. Inhalation causes anoxia due to the formation of methemoglobin and hematuria.
Chronic:
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death.
Highly flammable. Harmful by inhalation and if swallowed.Light sensitive.Air sensitive.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
May cause skin irritation. May be absorbed through the skin in harmful amounts. May cause allergic contact dermatitis.
Ingestion:
Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed. This product contains nitrite which may cause methemoglobinemia.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation.
Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. This product contains nitrite which may cause methemoglobinemia. Inhalation causes anoxia due to the formation of methemoglobin and hematuria.
Chronic:
May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood.
Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood.
Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Liquid will float and may reignite on the surface of water. Flammable liquid and vapor. Containers may explode when heated. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire.
Extinguishing Media:
Dry chemical, alcohol foam, carbon dioxide.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Liquid will float and may reignite on the surface of water. Flammable liquid and vapor. Containers may explode when heated. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire.
Extinguishing Media:
Dry chemical, alcohol foam, carbon dioxide.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation. Keep unnecessary and unprotected personnel away.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation. Keep unnecessary and unprotected personnel away.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with air and sunlight. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Keep under a nitrogen blanket. Refrigerator/flammables.
Store protected from moisture. Store protected from light and air.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with air and sunlight. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed container. Keep under a nitrogen blanket. Refrigerator/flammables.
Store protected from moisture. Store protected from light and air.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 110-46-3: CAS# 497-19-8: Russia: 5 mg/m3 TWA Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 110-46-3: CAS# 497-19-8: Russia: 5 mg/m3 TWA Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear light yellow
Odor: penetrating odor - fruity odor
pH: Not applicable.
Vapor Pressure: 35 mbar @ 20 deg C
Viscosity: Not available.
Boiling Point: 98 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: 210 deg C ( 410.00 deg F)
Flash Point: 10 deg C ( 50.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Practically insoluble in water.
Specific Gravity/Density: 0.88 @ 20C
Molecular Formula: C5H11NO2
Molecular Weight: 117.15
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Unstable. May decompose on exposure to moist air or water.
Decomposes on exposure to air and light.
Conditions to Avoid:
High temperatures, light, ignition sources, moisture, exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, alcohols, alkalies, bromides, antipyrine, potassium iodide, Attacks metals in the presence of moisture., ferrous salts.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Unstable. May decompose on exposure to moist air or water.
Decomposes on exposure to air and light.
Conditions to Avoid:
High temperatures, light, ignition sources, moisture, exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong reducing agents, alcohols, alkalies, bromides, antipyrine, potassium iodide, Attacks metals in the presence of moisture., ferrous salts.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 110-46-3: NT0187500 CAS# 497-19-8: VZ4050000 LD50/LC50:
CAS# 110-46-3: Inhalation, mouse: LC50 = 1430 ppm/30M; Inhalation, rat: LC50 = 716 ppm/4H; Oral, mouse: LD50 = 852 mg/kg; Oral, rat: LD50 = 505 mg/kg.
CAS# 497-19-8: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 50 mg Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 1200 mg/m3/2H; Inhalation, rat: LC50 = 2300 mg/m3/2H; Oral, mouse: LD50 = 6600 mg/kg; Oral, mouse: LD50 = 6600 mg/kg; Oral, rat: LD50 = 4090 mg/kg.
Carcinogenicity:
Isoamyl nitrite - Not listed by ACGIH, IARC, or NTP.
Sodium carbonate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 110-46-3: NT0187500 CAS# 497-19-8: VZ4050000 LD50/LC50:
CAS# 110-46-3: Inhalation, mouse: LC50 = 1430 ppm/30M; Inhalation, rat: LC50 = 716 ppm/4H; Oral, mouse: LD50 = 852 mg/kg; Oral, rat: LD50 = 505 mg/kg.
CAS# 497-19-8: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 50 mg Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, mouse: LC50 = 1200 mg/m3/2H; Inhalation, rat: LC50 = 2300 mg/m3/2H; Oral, mouse: LD50 = 6600 mg/kg; Oral, mouse: LD50 = 6600 mg/kg; Oral, rat: LD50 = 4090 mg/kg.
Carcinogenicity:
Isoamyl nitrite - Not listed by ACGIH, IARC, or NTP.
Sodium carbonate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: AMYL NITRITE
Hazard Class: 3
UN Number: 1113
Packing Group: II
IMO
Shipping Name: AMYL NITRITE
Hazard Class: 3.2
UN Number: 1113
Packing Group: II
RID/ADR
Shipping Name: AMYL NITRITES
Hazard Class: 3
UN Number: 1113
Packing group: II
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN F
Risk Phrases:
R 11 Highly flammable.
R 20/22 Harmful by inhalation and if swallowed.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 24 Avoid contact with skin.
S 46 If swallowed, seek medical advice immediately
and show this container or label.
WGK (Water Danger/Protection)
CAS# 110-46-3: 2
CAS# 497-19-8: 1
Canada
CAS# 110-46-3 is listed on Canadas DSL List.
CAS# 497-19-8 is listed on Canadas DSL List.
CAS# 110-46-3 is not listed on Canadas Ingredient Disclosure List.
CAS# 497-19-8 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 110-46-3 is listed on the TSCA inventory.
CAS# 497-19-8 is listed on the TSCA inventory.
