Name:
Isobutyl alcohol
Synonym:
1-Hydroxymethylpropane; Isobutanol; Isopropylcarbinol; 2-Methyl-1-propanol; IBA
CAS:
78-83-1
Section 1 - Chemical Product
MSDS Name:Isobutyl alcohol
Synonym:1-Hydroxymethylpropane; Isobutanol; Isopropylcarbinol; 2-Methyl-1-propanol; IBA
Synonym:1-Hydroxymethylpropane; Isobutanol; Isopropylcarbinol; 2-Methyl-1-propanol; IBA
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 78-83-1 | Isobutyl alcohol | 99 | 201-148-0 |
| Hazard Symbols: XI Risk Phrases: 10 37/38 41 67 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Irritating to respiratory system and skin. Risk of serious damage to eyes. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
May cause severe eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
Aspiration hazard. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause corneal abnormalities and loss of appetite and weight. May cause burning sensation in the chest.
Chronic:
Not available.
Flammable. Irritating to respiratory system and skin. Risk of serious damage to eyes. Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
May cause severe eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
Aspiration hazard. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause corneal abnormalities and loss of appetite and weight. May cause burning sensation in the chest.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid immediately.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective.
Material is lighter than water and a fire may be spread by the use of water. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Dry chemical, alcohol foam, carbon dioxide.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective.
Material is lighter than water and a fire may be spread by the use of water. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Dry chemical, alcohol foam, carbon dioxide.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 78-83-1: United Kingdom, WEL - TWA: 50 ppm TWA; 154 mg/m3 TWA United Kingdom, WEL - STEL: 75 ppm STEL; 231 mg/m3 STEL United States OSHA: 100 ppm TWA; 300 mg/m3 TWA Belgium - TWA: 50 ppm VLE; 154 mg/m3 VLE France - VME: 50 ppm VME; 150 mg/m3 VME Germany: 100 ppm TWA; 310 mg/m3 TWA Japan: 50 ppm OEL; 150 mg/m3 OEL Malaysia: 50 ppm TWA; 152 mg/m3 TWA Netherlands: 50 ppm MAC; 150 mg/m3 MAC Russia: 10 mg/m3 TWA Spain: 50 ppm VLA-ED; 154 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 78-83-1: United Kingdom, WEL - TWA: 50 ppm TWA; 154 mg/m3 TWA United Kingdom, WEL - STEL: 75 ppm STEL; 231 mg/m3 STEL United States OSHA: 100 ppm TWA; 300 mg/m3 TWA Belgium - TWA: 50 ppm VLE; 154 mg/m3 VLE France - VME: 50 ppm VME; 150 mg/m3 VME Germany: 100 ppm TWA; 310 mg/m3 TWA Japan: 50 ppm OEL; 150 mg/m3 OEL Malaysia: 50 ppm TWA; 152 mg/m3 TWA Netherlands: 50 ppm MAC; 150 mg/m3 MAC Russia: 10 mg/m3 TWA Spain: 50 ppm VLA-ED; 154 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless, oily
Odor: mild odor - sweetish odor - slightly musty
pH: Not available.
Vapor Pressure: 10.5 mm Hg @ 25 deg C
Viscosity: 4 cps @ 20 deg C
Boiling Point: 107-108 deg C
Freezing/Melting Point: -108 deg C
Autoignition Temperature: 415 deg C ( 779.00 deg F)
Flash Point: 28 deg C ( 82.40 deg F)
Explosion Limits, lower: 1.7
Explosion Limits, upper: 10.6
Decomposition Temperature: Not available.
Solubility in water: Partially soluble.
Specific Gravity/Density: 0.802
Molecular Formula: C4H10O
Molecular Weight: 74.12
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. May form unstable peroxides.
Conditions to Avoid:
Ignition sources, excess heat, prolonged exposure to air, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures. May form unstable peroxides.
Conditions to Avoid:
Ignition sources, excess heat, prolonged exposure to air, confined spaces.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 78-83-1: NP9625000 LD50/LC50:
CAS# 78-83-1: Inhalation, mouse: LC50 = 15500 mg/m3/2H; Inhalation, rabbit: LC50 = 2630 mg/m3/4H; Inhalation, rat: LC50 = 19200 mg/m3/4H; Oral, mouse: LD50 = 3500 mg/kg; Oral, rabbit: LD50 = 74.1 mg/kg; Oral, rat: LD50 = 2460 mg/kg; Skin, rabbit: LD50 = 3400 mg/kg.
Carcinogenicity:
Isobutyl alcohol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 78-83-1: NP9625000 LD50/LC50:
CAS# 78-83-1: Inhalation, mouse: LC50 = 15500 mg/m3/2H; Inhalation, rabbit: LC50 = 2630 mg/m3/4H; Inhalation, rat: LC50 = 19200 mg/m3/4H; Oral, mouse: LD50 = 3500 mg/kg; Oral, rabbit: LD50 = 74.1 mg/kg; Oral, rat: LD50 = 2460 mg/kg; Skin, rabbit: LD50 = 3400 mg/kg.
Carcinogenicity:
Isobutyl alcohol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: 1430g/L; 96HFish: Fathead Minnow: 1430g/L; 96H
Fish: Fathead Minnow: 1430g/L; 96HFish: Fathead Minnow: 1430g/L; 96H
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: ISOBUTANOL
Hazard Class: 3
UN Number: 1212
Packing Group: III
IMO
Shipping Name: ISOBUTANOL
Hazard Class: 3.3
UN Number: 1212
Packing Group: III
RID/ADR
Shipping Name: ISOBUTANOL
Hazard Class: 3
UN Number: 1212
Packing group: III
USA RQ: CAS# 78-83-1: 5000 lb final RQ; 2270 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 10 Flammable.
R 37/38 Irritating to respiratory system and skin.
R 41 Risk of serious damage to eyes.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 13 Keep away from food, drink and animal feeding
stuffs.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
S 46 If swallowed, seek medical advice immediately
and show this container or label.
WGK (Water Danger/Protection)
CAS# 78-83-1: 1
Canada
CAS# 78-83-1 is listed on Canadas DSL List.
CAS# 78-83-1 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 78-83-1 is listed on the TSCA inventory.
