Name:
Isopropyl Ether 98+% Stabilized with 100-200 ppm BHT
Synonym:
Diisopropyl ether, DIPE, 2-Isopropoxypropan
CAS:
108-20-3
Section 1 - Chemical Product
MSDS Name:Isopropyl Ether 98+% Stabilized with 100-200 ppm BHT
Synonym:Diisopropyl ether, DIPE, 2-Isopropoxypropan
Synonym:Diisopropyl ether, DIPE, 2-Isopropoxypropan
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 108-20-3 | Isopropyl ether | 98.0+ | 203-560-6 |
| Hazard Symbols: F Risk Phrases: 11 19 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. May form explosive peroxides.
Potential Health Effects
Eye:
Causes mild eye irritation.
Skin:
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
Aspiration hazard. May cause irritation of the digestive tract.
Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May cause effects similar to those of acute inhalation.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. May cause narcotic effects in high concentration. May cause drowsiness, unconsciousness, and central nervous system depression.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation may cause effects similar to those of acute inhalation.
Highly flammable. May form explosive peroxides.
Potential Health Effects
Eye:
Causes mild eye irritation.
Skin:
May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
Aspiration hazard. May cause irritation of the digestive tract.
Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May cause effects similar to those of acute inhalation.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. May cause respiratory tract irritation. May cause narcotic effects in high concentration. May cause drowsiness, unconsciousness, and central nervous system depression.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation may cause effects similar to those of acute inhalation.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid if irritation develops or persists. Wash clothing before reuse. Rinse area with large amounts of water for at least 15 minutes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Get medical aid if irritation develops or persists. Wash clothing before reuse. Rinse area with large amounts of water for at least 15 minutes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool.
Vapor may cause flash fire. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water.
Forms peroxides of unknown stability. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam.
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool.
Vapor may cause flash fire. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water.
Forms peroxides of unknown stability. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use only in a well-ventilated area.
Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Loosen closure cautiously before opening. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Store protected from light. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Purge container with nitrogen before resealing. Keep dry. Keep under a nitrogen blanket.
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Flammables-area.
Wash thoroughly after handling. Use only in a well-ventilated area.
Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Loosen closure cautiously before opening. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Store protected from light. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Purge container with nitrogen before resealing. Keep dry. Keep under a nitrogen blanket.
Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: clear, colorless
Odor: Ethereal odor
pH: Not available.
Vapor Pressure: 150 mm Hg @25
Viscosity: 0.38 mPas 25 deg C
Boiling Point: 68 deg C @ 760.00mm Hg
Freezing/Melting Point: 0 deg C
Autoignition Temperature: 443 deg C ( 829.40 deg F)
Flash Point: -29 deg C ( -20.20 deg F)
Explosion Limits, lower: 1.10 vol %
Explosion Limits, upper: 21.00 vol %
Decomposition Temperature:
Solubility in water: 0.9 G/100ML (20C)
Specific Gravity/Density: .7250g/cm3
Molecular Formula: C6H14O
Molecular Weight: 102.18
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Peroxide formation may occur in containers that have been opened and remain in storage. Normally stable; however, on long term storage, materials containing similar functional groups form peroxides of unknown stability. May form explosive peroxides on prolonged storage.
Conditions to Avoid:
Incompatible materials, light, ignition sources, exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, chlorosulfonic acid, nitric acid, propionyl chloride.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, peroxides.
Hazardous Polymerization: Has not been reported.
Peroxide formation may occur in containers that have been opened and remain in storage. Normally stable; however, on long term storage, materials containing similar functional groups form peroxides of unknown stability. May form explosive peroxides on prolonged storage.
Conditions to Avoid:
Incompatible materials, light, ignition sources, exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, chlorosulfonic acid, nitric acid, propionyl chloride.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, peroxides.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 108-20-3: TZ5425000 LD50/LC50:
CAS# 108-20-3: Inhalation, mouse: LC50 = 131 gm/m3; Inhalation, rabbit: LC50 = 121 gm/m3; Inhalation, rat: LC50 = 162 gm/m3; Oral, rat: LD50 = 8470 mg/kg; Skin, rabbit: LD50 = 20 mL/kg.
Carcinogenicity:
Isopropyl ether - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.
CAS# 108-20-3: TZ5425000 LD50/LC50:
CAS# 108-20-3: Inhalation, mouse: LC50 = 131 gm/m3; Inhalation, rabbit: LC50 = 121 gm/m3; Inhalation, rat: LC50 = 162 gm/m3; Oral, rat: LD50 = 8470 mg/kg; Skin, rabbit: LD50 = 20 mL/kg.
Carcinogenicity:
Isopropyl ether - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 91.7 mg/L; 96 Hr.; Flow-throughFish: Bluegill/Sunfish: LC50 = 6600-7000 mg/L; 96 Hr.; UnspecifiedFish: Goldfish: LC50 = 380 mg/L; 24 Hr.; Modified ASTMD1345Bacteria: Phytobacterium phosphoreum: EC50 = 500 mg/L; 5 Minutes; Microtox testWater danger/protection: WGK 1 Fathead minnow (Pimephales promelas) LC50: 91.7 mg/l/96hr
Fish: Fathead Minnow: LC50 = 91.7 mg/L; 96 Hr.; Flow-throughFish: Bluegill/Sunfish: LC50 = 6600-7000 mg/L; 96 Hr.; UnspecifiedFish: Goldfish: LC50 = 380 mg/L; 24 Hr.; Modified ASTMD1345Bacteria: Phytobacterium phosphoreum: EC50 = 500 mg/L; 5 Minutes; Microtox testWater danger/protection: WGK 1 Fathead minnow (Pimephales promelas) LC50: 91.7 mg/l/96hr
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: DIISOPROPYL ETHER
Hazard Class: 3
UN Number: 1159
Packing Group: II
IMO
Shipping Name: DIISOPROPYL ETHER
Hazard Class: 3.1
UN Number: 1159
Packing Group: II
RID/ADR
Shipping Name: DIISOPROPYL ETHER
Dangerous Goods Code: 3(3B)
UN Number: 1159
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F
Risk Phrases:
R 11 Highly flammable.
R 19 May form explosive peroxides.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 108-20-3: 1
United Kingdom Occupational Exposure Limits
CAS# 108-20-3: OES-United Kingdom, TWA 250 ppm TWA; 1060 mg/m3 TWA
CAS# 108-20-3: OES-United Kingdom, STEL 310 ppm STEL; 1310 mg/m3
STEL
Canada
CAS# 108-20-3 is listed on Canadas DSL List.
CAS# 108-20-3 is listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 108-20-3: OEL-AUSTRALIA:TWA 250 ppm (1050 mg/m3);STEL 310 ppm (13
20 mg/m3)
OEL-BELGIUM:TWA 250 ppm (1040 mg/m3);STEL 310 ppm (1300 mg/m3)
OEL-DENMARK:TWA 250 ppm (1050 mg/m3)
OEL-FRANCE:TWA 250 ppm (1050 mg/m3)
OEL-GERMANY:TWA 500 ppm (2100 mg/m3)
OEL-THE NETHERLANDS:TWA 250 ppm (1050 mg/m3) JAN9
OEL-THE PHILIPPINES:TWA 500 ppm (2100 mg/m3) JAN9
OEL-POLAND:TWA 1000 mg/m3
OEL-RUSSIA:STEL 100 mg/m3
OEL-SWITZERLAND:TWA 250 ppm (1050 mg/m3)
OEL-TURKEY:TWA 500 ppm (2100 mg/m3)
OEL-UNITED KINGDOM:TWA 250 ppm (1050 mg/m3);STEL 310 ppm
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 108-20-3 is listed on the TSCA inventory.
