Name:
Isopropyl-dimethyl-chlorosilane
Synonym:
2-Propanol; Isopropyl alcohol; IPA
CAS:
67-63-0
Section 1 - Chemical Product
MSDS Name:Isopropyl-dimethyl-chlorosilane
Synonym:2-Propanol; Isopropyl alcohol; IPA
Synonym:2-Propanol; Isopropyl alcohol; IPA
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 67-63-0 | Isopropyl alcohol | 70 % | 200-661-7 |
| Hazard Symbols: F Risk Phrases: 11 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.
Skin:
Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause irritation with pain and stinging, especially if the skin is abraded.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory tract irritation. May cause narcotic effects.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis.
Highly flammable.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.
Skin:
Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause irritation with pain and stinging, especially if the skin is abraded.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory tract irritation. May cause narcotic effects.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower lids. Get medical aid immediately.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Urine acetone test may be helpful in diagnosis.
Antidote: None reported
Skin:
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Urine acetone test may be helpful in diagnosis.
Antidote: None reported
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Containers may explode in the heat of a fire. This chemical poses an explosion hazard. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available.
Upper: Not available.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. Containers may explode in the heat of a fire. This chemical poses an explosion hazard. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available.
Upper: Not available.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.
Spills/Leaks:
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.
Section 7 - HANDLING and STORAGE
Handling:
Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation.
Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Flammables-area.
Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation.
Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements must be followed whenever workplace conditions warrant a respirators use.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements must be followed whenever workplace conditions warrant a respirators use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: Not available.
Odor: Characteristic odor.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: 2.07
Evaporation Rate: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Decomposition Temperature: Not available.
Solubility: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: Not available.
Molecular Weight: Not available.
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. This material may be sensitive to peroxide formation.
Conditions to Avoid:
Ignition sources, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents, acetaldeyde, chlorine, ethylene oxide, acids and isocyanates, hydrogen + palladium, nitroform, oleum, phosgene, potassium t-butoxide, oxygen, trinitromethane, barium perchlorate, tetrafluoroborate, chromium trioxide, sodium dichromate + sulfuric acid, aluminum, and aluminum triisopropoxide. Isopropyl alcohol has been reported to be susceptible to autoxidation and should therefore be considered peroxidizable. It Refer to the NFPA manual for more specific information.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
Stable under normal temperatures and pressures. This material may be sensitive to peroxide formation.
Conditions to Avoid:
Ignition sources, exposure to moist air or water.
Incompatibilities with Other Materials:
Oxidizing agents, acetaldeyde, chlorine, ethylene oxide, acids and isocyanates, hydrogen + palladium, nitroform, oleum, phosgene, potassium t-butoxide, oxygen, trinitromethane, barium perchlorate, tetrafluoroborate, chromium trioxide, sodium dichromate + sulfuric acid, aluminum, and aluminum triisopropoxide. Isopropyl alcohol has been reported to be susceptible to autoxidation and should therefore be considered peroxidizable. It Refer to the NFPA manual for more specific information.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 67-63-0: NT8050000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 67-63-0: Oral, mouse: LD50 = 3600 mg/kg; Oral, rabbit: LD50 = 6410 mg/kg; Oral, rat: LD50 = 5045 mg/kg; Skin, rabbit: LD50 = 12800 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Isopropyl alcohol - IARC: Group 3 carcinogen Water - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
CAS# 67-63-0: NT8050000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 67-63-0: Oral, mouse: LD50 = 3600 mg/kg; Oral, rabbit: LD50 = 6410 mg/kg; Oral, rat: LD50 = 5045 mg/kg; Skin, rabbit: LD50 = 12800 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Isopropyl alcohol - IARC: Group 3 carcinogen Water - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
For further information, contact Fisher Scientific.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
CDG/CPL
IMO
Not regulated as a hazardous material.
IATA
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Canadian TDG
No information available.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F
Risk Phrases:
R 11 Highly flammable.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 67-63-0: 1
CAS# 7732-18-5:
Canada
CAS# 67-63-0 is listed on Canadas DSL/NDSL List.
CAS# 7732-18-5 is listed on Canadas DSL/NDSL List.
WHMIS: Not available.
CAS# 67-63-0 is listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 67-63-0:. OEL-AUSTRALIA:TWA 400 ppm (980 mg/m3);STEL 500 ppm (12
25 mg/m3). OEL-BELGIUM:TWA 400 ppm (985 mg/m3);STEL 500 ppm (1230 mg/m
3). OEL-DENMARK:TWA 200 ppm (490 mg/m3);Skin. OEL-FRANCE:STEL 400 ppm
(980 mg/m3). OEL-GERMANY:TWA 400 ppm (980 mg/m3). OEL-JAPAN:STEL 400 p
pm (980 mg/m3). OEL-THE NETHERLANDS:TWA 400 ppm (980 mg/m3);Skin. OEL-
THE PHILIPPINES:TWA 400 ppm (980 mg/m3). OEL-RUSSIA:STEL 400 ppm (10 m
g/m3). OEL-SWEDEN:TWA 150 ppm (350 mg/m3);STEL 250 ppm (600 mg/m3). OE
L-SWITZERLAND:TWA 400 ppm (980 mg/m3);STEL 800 ppm. OEL-TURKEY:TWA 200
ppm (500 mg/m3). OEL-UNITED KINGDOM:TWA 400 ppm (980 mg/m3);STEL 500
ppm;Skin. OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV. OE
L IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 67-63-0 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
