Name:
Lithium bis(trimethylsilyl)amide 1M solution in THF/cyclohexane
Synonym:
1,1,1,3,3,3-Hexamethyldisilazane Lithium Sal
CAS:
109-99-9
Section 1 - Chemical Product
MSDS Name:Lithium bis(trimethylsilyl)amide 1M solution in THF/cyclohexane
Synonym:1,1,1,3,3,3-Hexamethyldisilazane Lithium Sal
Synonym:1,1,1,3,3,3-Hexamethyldisilazane Lithium Sal
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 109-99-9 | Tetrahydrofuran | <78.29 | 203-726-8 |
| Hazard Symbols: F C Risk Phrases: 11 19 34 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. May form explosive peroxides. Causes burns.Air sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract. Vapors may cause dizziness or suffocation.
Chronic:
None
Highly flammable. May form explosive peroxides. Causes burns.Air sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract. Vapors may cause dizziness or suffocation.
Chronic:
None
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed.
Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Antidote: None reported.
Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
Antidote: None reported.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire.
Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire.
Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Do NOT use water directly on fire. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors.
Section 7 - HANDLING and STORAGE
Handling:
Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. If peroxide formation is suspected, do not open or move container. Avoid contact with air and sunlight. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Unused chemicals should not be returned to the container. Do not distill since this removes peroxide-inhibitors.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Regularly check inhibitor levels to maintain peroxide levels below 1%. Do not break the seal on the container until it is needed. Label the container with the date it was first opened. Long-term storage is not recommended.
Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. If peroxide formation is suspected, do not open or move container. Avoid contact with air and sunlight. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Unused chemicals should not be returned to the container. Do not distill since this removes peroxide-inhibitors.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Regularly check inhibitor levels to maintain peroxide levels below 1%. Do not break the seal on the container until it is needed. Label the container with the date it was first opened. Long-term storage is not recommended.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 110-82-7: United Kingdom, WEL - TWA: 100 ppm TWA; 350 mg/m3 TWA United Kingdom, WEL - STEL: 300 ppm STEL; 1050 mg/m3 STEL United States OSHA: 300 ppm TWA; 1050 mg/m3 TWA Belgium - TWA: 300 ppm VLE; 1045 mg/m3 VLE France - VME: 300 ppm VME; 1050 mg/m3 VME France - VLE: 375 ppm VLE; 1300 mg/m3 VLE Germany: 200 ppm TWA; 700 mg/m3 TWA Japan: 150 ppm OEL; 520 mg/m3 OEL Malaysia: 300 ppm TWA; 1030 mg/m3 TWA Netherlands: 250 ppm MAC; 875 mg/m3 MAC Russia: 80 mg/m3 TWA Spain: 300 ppm VLA-ED; 1050 mg/m3 VLA-ED Spain: 600 ppm VLA-EC; 2100 mg/m3 VLA-EC CAS# 4039-32-1: United Kingdom, WEL - TWA: (listed as silica, amorphous): 6 mg/m3 (inhalable dust); 2.4 mg/m3 TWA (respirable dust) United Kingdom, WEL - STEL: (listed as silica, amorphous): 18 mg/ STEL (inhalable dust); 7.2 mg/m3 STEL (respirable dust) Russia: (listed as silica, amorphous): 1 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC CAS# 110-82-7: United Kingdom, WEL - TWA: 100 ppm TWA; 350 mg/m3 TWA United Kingdom, WEL - STEL: 300 ppm STEL; 1050 mg/m3 STEL United States OSHA: 300 ppm TWA; 1050 mg/m3 TWA Belgium - TWA: 300 ppm VLE; 1045 mg/m3 VLE France - VME: 300 ppm VME; 1050 mg/m3 VME France - VLE: 375 ppm VLE; 1300 mg/m3 VLE Germany: 200 ppm TWA; 700 mg/m3 TWA Japan: 150 ppm OEL; 520 mg/m3 OEL Malaysia: 300 ppm TWA; 1030 mg/m3 TWA Netherlands: 250 ppm MAC; 875 mg/m3 MAC Russia: 80 mg/m3 TWA Spain: 300 ppm VLA-ED; 1050 mg/m3 VLA-ED Spain: 600 ppm VLA-EC; 2100 mg/m3 VLA-EC CAS# 4039-32-1: United Kingdom, WEL - TWA: (listed as silica, amorphous): 6 mg/m3 (inhalable dust); 2.4 mg/m3 TWA (respirable dust) United Kingdom, WEL - STEL: (listed as silica, amorphous): 18 mg/ STEL (inhalable dust); 7.2 mg/m3 STEL (respirable dust) Russia: (listed as silica, amorphous): 1 mg/m3 TWA Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: not available
Odor: None reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: -17 deg C ( 1.40 deg F)
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water: reacts with water.
Specific Gravity/Density: .8150g/cm3
Molecular Formula: C6H18LiNSi2
Molecular Weight: 167.2447
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. On long term storage, substances with similar functional groups form explosive peroxides. Explosive peroxides may form on concentration. Peroxides can be detonated by friction, impact, or heating. Tends to form explosive peroxides; especially when anhydrous. Peroxide formation may occur in containers that have been opened and remain in storage.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen, silicon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures. On long term storage, substances with similar functional groups form explosive peroxides. Explosive peroxides may form on concentration. Peroxides can be detonated by friction, impact, or heating. Tends to form explosive peroxides; especially when anhydrous. Peroxide formation may occur in containers that have been opened and remain in storage.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen, silicon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 109-99-9: LU5950000 CAS# 110-82-7: GU6300000 CAS# 4039-32-1 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 110-82-7: Draize test, rabbit, skin: 1548 mg/2D (Intermittent); Inhalation, mouse: LC50 = 70000 mg/m3/2H; Oral, mouse: LD50 = 813 mg/kg; Oral, rat: LD50 = 12705 mg/kg.
CAS# 4039-32-1.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Cyclohexane - Not listed by ACGIH, IARC, or NTP.
Lithium bis(trimethylsilyl)amide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 109-99-9: LU5950000 CAS# 110-82-7: GU6300000 CAS# 4039-32-1 unlisted.
LD50/LC50:
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
CAS# 110-82-7: Draize test, rabbit, skin: 1548 mg/2D (Intermittent); Inhalation, mouse: LC50 = 70000 mg/m3/2H; Oral, mouse: LD50 = 813 mg/kg; Oral, rat: LD50 = 12705 mg/kg.
CAS# 4039-32-1.
Carcinogenicity:
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Cyclohexane - Not listed by ACGIH, IARC, or NTP.
Lithium bis(trimethylsilyl)amide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.*
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
IMO
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3.2 (8)
UN Number: 2924
Packing Group: II
RID/ADR
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3
UN Number: 2924
Packing group: II
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
USA RQ: CAS# 110-82-7: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 19 May form explosive peroxides.
R 34 Causes burns.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 109-99-9: 1
CAS# 110-82-7: 1
CAS# 4039-32-1: No information available.
Canada
CAS# 109-99-9 is listed on Canadas DSL List.
CAS# 110-82-7 is listed on Canadas DSL List.
CAS# 4039-32-1 is listed on Canadas NDSL List.
CAS# 109-99-9 is listed on Canadas Ingredient Disclosure List.
CAS# 110-82-7 is listed on Canadas Ingredient Disclosure List.
CAS# 4039-32-1 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 109-99-9 is listed on the TSCA inventory.
CAS# 110-82-7 is listed on the TSCA inventory.
CAS# 4039-32-1 is listed on the TSCA inventory.
