Name:
Methyl iodide
Synonym:
Iodomethane
CAS:
74-88-4
Section 1 - Chemical Product
MSDS Name:Methyl iodide
Synonym:Iodomethane
Synonym:Iodomethane
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 74-88-4 | Iodomethane | >98 | 200-819-5 |
| Hazard Symbols: T Risk Phrases: 21 23/25 37/38 40 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful in contact with skin. Toxic by inhalation and if swallowed.
Irritating to respiratory system and skin. Limited evidence of a carcinogenic effect.Light sensitive.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause effects similar to those for inhalation exposure.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation. Animal studies have reported the development of tumors.
Harmful in contact with skin. Toxic by inhalation and if swallowed.
Irritating to respiratory system and skin. Limited evidence of a carcinogenic effect.Light sensitive.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause effects similar to those for inhalation exposure.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Chronic inhalation may cause effects similar to those of acute inhalation. Animal studies have reported the development of tumors.
Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
POISON material. If inhaled, get medical aid immediately. Remove victim to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
POISON material. If inhaled, get medical aid immediately. Remove victim to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Substance is noncombustible.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Evacuate unnecessary personnel.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Evacuate unnecessary personnel.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Do not breathe vapor. Use only with adequate ventilation or respiratory protection.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Do not breathe vapor. Use only with adequate ventilation or respiratory protection.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 74-88-4: United Kingdom, WEL - TWA: 2 ppm TWA; 12 mg/m3 TWA United Kingdom, WEL - STEL: 6 ppm STEL; 36 mg/m3 STEL United States OSHA: 5 ppm TWA; 28 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 12 mg/m3 VLE France - VME: 2 ppm VME; 12 mg/m3 VME Germany: 0.3 ppm TWA; 2 mg/m3 TWA Germany: Skin absorber Malaysia: 2 ppm TWA; 12 mg/m3 TWA Netherlands: 2 ppm MAC; 10 mg/m3 MAC Spain: 2 ppm VLA-ED; 12 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 74-88-4: United Kingdom, WEL - TWA: 2 ppm TWA; 12 mg/m3 TWA United Kingdom, WEL - STEL: 6 ppm STEL; 36 mg/m3 STEL United States OSHA: 5 ppm TWA; 28 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 12 mg/m3 VLE France - VME: 2 ppm VME; 12 mg/m3 VME Germany: 0.3 ppm TWA; 2 mg/m3 TWA Germany: Skin absorber Malaysia: 2 ppm TWA; 12 mg/m3 TWA Netherlands: 2 ppm MAC; 10 mg/m3 MAC Spain: 2 ppm VLA-ED; 12 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: clear, colorless to pale yellow
Odor: Sweet, ethereal
pH: Not available.
Vapor Pressure: 375 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 42.5 deg C @ 760 mm Hg
Freezing/Melting Point: -66 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature: 270 deg C
Solubility in water: 14 g/1000 ml @ 20C
Specific Gravity/Density: 2.28 @ 20C
Molecular Formula: CH3I
Molecular Weight: 141.94
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. May discolor on exposure to light. Turns reddish-brown on exposure to light.
Conditions to Avoid:
Light, moisture, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen iodide, iodide.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures. May discolor on exposure to light. Turns reddish-brown on exposure to light.
Conditions to Avoid:
Light, moisture, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen iodide, iodide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 74-88-4: PA9450000 LD50/LC50:
CAS# 74-88-4: Dermal, guinea pig: LD50 = 800 mg/kg; Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg Severe; Inhalation, mouse: LC50 = 5 gm/m3/57M-C; Inhalation, mouse: LC50 = 5000 mg/m3/57M; Inhalation, rat: LC50 = 1300 mg/m3/4H; Oral, rat: LD50 = 76 mg/kg.
Not available.
Carcinogenicity:
Iodomethane - California: carcinogen, initial date 4/1/88 Other:
See actual entry in RTECS for complete information.
CAS# 74-88-4: PA9450000 LD50/LC50:
CAS# 74-88-4: Dermal, guinea pig: LD50 = 800 mg/kg; Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg Severe; Inhalation, mouse: LC50 = 5 gm/m3/57M-C; Inhalation, mouse: LC50 = 5000 mg/m3/57M; Inhalation, rat: LC50 = 1300 mg/m3/4H; Oral, rat: LD50 = 76 mg/kg.
Not available.
Carcinogenicity:
Iodomethane - California: carcinogen, initial date 4/1/88 Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: METHYL IODIDE
Hazard Class: 6.1
UN Number: 2644
Packing Group:
IMO
Shipping Name: METHYL IODIDE
Hazard Class: 6.1
UN Number: 2644
Packing Group: I
RID/ADR
Shipping Name: METHYL IODIDE
Hazard Class: 6.1
UN Number: 2644
Packing group: I
USA RQ: CAS# 74-88-4: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 21 Harmful in contact with skin.
R 23/25 Toxic by inhalation and if swallowed.
R 37/38 Irritating to respiratory system and skin.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 38 In case of insufficient ventilation, wear
suitable respiratory equipment.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 74-88-4: 2
Canada
CAS# 74-88-4 is listed on Canadas DSL List.
CAS# 74-88-4 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 74-88-4 is listed on the TSCA inventory.
