Name:
Methylamine 2m solution in methanol
Synonym:
CAS:
67-56-1
Section 1 - Chemical Product
MSDS Name:Methylamine 2m solution in methanol
Synonym:
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 67-56-1 | Methanol | 93.8% | 200-659-6 |
| Hazard Symbols: T F Risk Phrases: 11 23/24/25 36/37/38 39/23/24/25 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Highly flammable. Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Toxic : danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause painful sensitization to light. Lachrymator (substance which increases the flow of tears).
Skin:
Causes moderate skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion:
May be fatal or cause blindness if swallowed. Cannot be made non-poisonous. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause cardiopulmonary system effects.
Inhalation:
May cause adverse central nervous system effects including headache, convulsions, and possible death. May cause visual impairment and possible permanent blindness. Causes irritation of mucous membrane.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. Chronic exposure may cause reproductive disorders and teratogenic effects. Laboratory experiments have resulted in mutagenic effects.
Highly flammable. Toxic by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Toxic : danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
Potential Health Effects
Eye:
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause painful sensitization to light. Lachrymator (substance which increases the flow of tears).
Skin:
Causes moderate skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion:
May be fatal or cause blindness if swallowed. Cannot be made non-poisonous. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause cardiopulmonary system effects.
Inhalation:
May cause adverse central nervous system effects including headache, convulsions, and possible death. May cause visual impairment and possible permanent blindness. Causes irritation of mucous membrane.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. Chronic exposure may cause reproductive disorders and teratogenic effects. Laboratory experiments have resulted in mutagenic effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Effects may be delayed. Ethanol may inhibit methanol metabolism.
Treat symptomatically and supportively.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Effects may be delayed. Ethanol may inhibit methanol metabolism.
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Vapors may be heavier than air.
They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Use flooding quantities of water as spray.
Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Vapors may be heavier than air.
They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Use flooding quantities of water as spray.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Use water spray to disperse the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Spills/Leaks:
Use water spray to disperse the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Do not use combustible materials such as sawdust. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.
Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 67-56-1: United Kingdom, WEL - TWA: 200 ppm TWA; 266 mg/m3 TWA United Kingdom, WEL - STEL: 250 ppm STEL; 333 mg/m3 STEL United States OSHA: 200 ppm TWA; 260 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 266 mg/m3 VLE Belgium - STEL: 250 ppm VLE; 333 mg/m3 VLE France - VME: 200 ppm VME; 260 mg/m3 VME France - VLE: 1000 ppm VLE; 1300 mg/m3 VLE Germany: 200 ppm TWA; 270 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 260 mg/m3 OEL Malaysia: 200 ppm TWA; 262 mg/m3 TWA Netherlands: 200 ppm MAC; 260 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 200 ppm VLA-ED; 266 mg/m3 VLA-ED Spain: 250 ppm VLA-EC; 333 mg/m3 VLA-EC CAS# 74-89-5: United States OSHA: 10 ppm TWA; 12 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 6.6 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 19 mg/m3 VLE France - VLE: 10 ppm VLE; 12 mg/m3 VLE Germany: 10 ppm TWA; 13 mg/m3 TWA Japan: 10 ppm OEL; 13 mg/m3 OEL Malaysia: 5 ppm TWA; 6.4 mg/m3 TWA Netherlands: 15 ppm STEL; 19 mg/m3 STEL Netherlands: 5 ppm MAC; 6.4 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 5 ppm VLA-ED; 6.5 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 19 mg/m3 VLA-EC Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 67-56-1: United Kingdom, WEL - TWA: 200 ppm TWA; 266 mg/m3 TWA United Kingdom, WEL - STEL: 250 ppm STEL; 333 mg/m3 STEL United States OSHA: 200 ppm TWA; 260 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 266 mg/m3 VLE Belgium - STEL: 250 ppm VLE; 333 mg/m3 VLE France - VME: 200 ppm VME; 260 mg/m3 VME France - VLE: 1000 ppm VLE; 1300 mg/m3 VLE Germany: 200 ppm TWA; 270 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 260 mg/m3 OEL Malaysia: 200 ppm TWA; 262 mg/m3 TWA Netherlands: 200 ppm MAC; 260 mg/m3 MAC Russia: 5 mg/m3 TWA Spain: 200 ppm VLA-ED; 266 mg/m3 VLA-ED Spain: 250 ppm VLA-EC; 333 mg/m3 VLA-EC CAS# 74-89-5: United States OSHA: 10 ppm TWA; 12 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 6.6 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 19 mg/m3 VLE France - VLE: 10 ppm VLE; 12 mg/m3 VLE Germany: 10 ppm TWA; 13 mg/m3 TWA Japan: 10 ppm OEL; 13 mg/m3 OEL Malaysia: 5 ppm TWA; 6.4 mg/m3 TWA Netherlands: 15 ppm STEL; 19 mg/m3 STEL Netherlands: 5 ppm MAC; 6.4 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 5 ppm VLA-ED; 6.5 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 19 mg/m3 VLA-EC Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: unpleasant odor
pH: Not available.
Vapor Pressure: 2.07Psi @20 deg C
Viscosity: Not available.
Boiling Point: 40 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 7 deg C ( 44.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 0.785
Molecular Formula: CH5N
Molecular Weight: 31.06
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to moist air or water.
Incompatibilities with Other Materials:
Magnesium, reducing agents, acid chlorides, alkali metals, acid anhydrides, acids, oxidizing agents, phosphorus halides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to moist air or water.
Incompatibilities with Other Materials:
Magnesium, reducing agents, acid chlorides, alkali metals, acid anhydrides, acids, oxidizing agents, phosphorus halides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 67-56-1: PC1400000 CAS# 74-89-5: PF6300000 LD50/LC50:
CAS# 67-56-1: Draize test, rabbit, eye: 40 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, rabbit: LC50 = 81000 mg/m3/14H; Inhalation, rat: LC50 = 64000 ppm/4H; Oral, mouse: LD50 = 7300 mg/kg; Oral, rabbit: LD50 = 14200 mg/kg; Oral, rat: LD50 = 5600 mg/kg; Skin, rabbit: LD50 = 15800 mg/kg.
CAS# 74-89-5: Inhalation, mouse: LC50 = 2400 mg/m3/2H; Inhalation, rat: LC50 = 448 ppm/2.5H; Oral, rat: LD50 = 100 mg/kg.
Carcinogenicity:
Methanol - Not listed by ACGIH, IARC, or NTP.
Methylamine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 67-56-1: PC1400000 CAS# 74-89-5: PF6300000 LD50/LC50:
CAS# 67-56-1: Draize test, rabbit, eye: 40 mg Moderate; Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, rabbit: LC50 = 81000 mg/m3/14H; Inhalation, rat: LC50 = 64000 ppm/4H; Oral, mouse: LD50 = 7300 mg/kg; Oral, rabbit: LD50 = 14200 mg/kg; Oral, rat: LD50 = 5600 mg/kg; Skin, rabbit: LD50 = 15800 mg/kg.
CAS# 74-89-5: Inhalation, mouse: LC50 = 2400 mg/m3/2H; Inhalation, rat: LC50 = 448 ppm/2.5H; Oral, rat: LD50 = 100 mg/kg.
Carcinogenicity:
Methanol - Not listed by ACGIH, IARC, or NTP.
Methylamine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Goldfish (fresh water), 250 ppm/11H, death.
Aquatic toxicity rating: TLm 96 >1000 ppm.
LC50(48hr) trout 8000 mg/l LC50(24hr) brine shrimp 10000 mg/l EC50(30min) Photobacterium phophoreum 51000-320000ppm, microtox test (Kaiser, K.L.E. et al. Water Pollut.Res.J.Can.1991, 26(3), 361-431) Bioaccummulation. Bioconcentration factor for golden ide<10 (Freitag, D. et al. Chemosphere 1985, 14, 1589-1616).
Goldfish (fresh water), 250 ppm/11H, death.
Aquatic toxicity rating: TLm 96 >1000 ppm.
LC50(48hr) trout 8000 mg/l LC50(24hr) brine shrimp 10000 mg/l EC50(30min) Photobacterium phophoreum 51000-320000ppm, microtox test (Kaiser, K.L.E. et al. Water Pollut.Res.J.Can.1991, 26(3), 361-431) Bioaccummulation. Bioconcentration factor for golden ide<10 (Freitag, D. et al. Chemosphere 1985, 14, 1589-1616).
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.*
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
IMO
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
RID/ADR
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3
UN Number: 2924
Packing group: II
USA RQ: CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ
USA RQ: CAS# 74-89-5: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T F
Risk Phrases:
R 11 Highly flammable.
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 39/23/24/25 Toxic : danger of very serious
irreversible effects through inhalation, in contact
with skin and if swallowed.
Safety Phrases:
S 7 Keep container tightly closed.
S 16 Keep away from sources of ignition - No
smoking.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 67-56-1: 1
CAS# 74-89-5: 2
Canada
CAS# 67-56-1 is listed on Canadas DSL List.
CAS# 74-89-5 is listed on Canadas DSL List.
CAS# 67-56-1 is listed on Canadas Ingredient Disclosure List.
CAS# 74-89-5 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 67-56-1 is listed on the TSCA inventory.
CAS# 74-89-5 is listed on the TSCA inventory.
