Name:
Methylamine 2M solution in THF
Synonym:
CAS:
74-89-5
Section 1 - Chemical Product
MSDS Name:Methylamine 2M solution in THF
Synonym:
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 74-89-5 | Methylamine | 6.2 | 200-820-0 |
| Hazard Symbols: XI F+ Risk Phrases: 12 19 36/37/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Extremely flammable. May form explosive peroxides. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Contact with eyes may cause severe irritation, and possible eye burns. Contact may cause ulceration of the conjunctiva and cornea.
Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin irritation. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation.
Chronic:
Prolonged or repeated eye contact may cause conjunctivitis.
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause liver and kidney damage.
Extremely flammable. May form explosive peroxides. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Contact with eyes may cause severe irritation, and possible eye burns. Contact may cause ulceration of the conjunctiva and cornea.
Lachrymator (substance which increases the flow of tears).
Skin:
Causes skin irritation. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation.
Chronic:
Prolonged or repeated eye contact may cause conjunctivitis.
Prolonged or repeated skin contact may cause defatting and dermatitis. May cause liver and kidney damage.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
Vapors can travel to a source of ignition and flash back. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Extremely flammable liquid and vapor. Forms peroxides of unknown stability. Containers may explode in the heat of a fire.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.
Vapors can travel to a source of ignition and flash back. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Extremely flammable liquid and vapor. Forms peroxides of unknown stability. Containers may explode in the heat of a fire.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use water spray to dilute spill to a non-flammable mixture. Remove all sources of ignition. Use a spark-proof tool.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use water spray to dilute spill to a non-flammable mixture. Remove all sources of ignition. Use a spark-proof tool.
Section 7 - HANDLING and STORAGE
Handling:
Use only in a well-ventilated area. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Use only in a chemical fume hood. Prevent build up of vapors to explosive concentration.
Storage:
Keep away from heat, sparks, and flame. Store in a cool place in the original container and protect from sunlight. Flammables-area.
Use only in a well-ventilated area. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Use only in a chemical fume hood. Prevent build up of vapors to explosive concentration.
Storage:
Keep away from heat, sparks, and flame. Store in a cool place in the original container and protect from sunlight. Flammables-area.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 74-89-5: United States OSHA: 10 ppm TWA; 12 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 6.6 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 19 mg/m3 VLE France - VLE: 10 ppm VLE; 12 mg/m3 VLE Germany: 10 ppm TWA; 13 mg/m3 TWA Japan: 10 ppm OEL; 13 mg/m3 OEL Malaysia: 5 ppm TWA; 6.4 mg/m3 TWA Netherlands: 15 ppm STEL; 19 mg/m3 STEL Netherlands: 5 ppm MAC; 6.4 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 5 ppm VLA-ED; 6.5 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 19 mg/m3 VLA-EC CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A NIOSH/MSHA approved or European Standard EN 149 air purifying respirator with an organic vapor cartridge or canister may be permissible under certain circumstances where airborne concentrations are expected.
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 74-89-5: United States OSHA: 10 ppm TWA; 12 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 6.6 mg/m3 VLE Belgium - STEL: 15 ppm VLE; 19 mg/m3 VLE France - VLE: 10 ppm VLE; 12 mg/m3 VLE Germany: 10 ppm TWA; 13 mg/m3 TWA Japan: 10 ppm OEL; 13 mg/m3 OEL Malaysia: 5 ppm TWA; 6.4 mg/m3 TWA Netherlands: 15 ppm STEL; 19 mg/m3 STEL Netherlands: 5 ppm MAC; 6.4 mg/m3 MAC Russia: 1 mg/m3 TWA Spain: 5 ppm VLA-ED; 6.5 mg/m3 VLA-ED Spain: 15 ppm VLA-EC; 19 mg/m3 VLA-EC CAS# 109-99-9: United Kingdom, WEL - TWA: 50 ppm TWA; 150 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 300 mg/m3 STEL United States OSHA: 200 ppm TWA; 590 mg/m3 TWA Belgium - TWA: 200 ppm VLE; 599 mg/m3 VLE Belgium - STEL: 100 ppm VLE; 300 mg/m3 VLE France - VME: 200 ppm VME; 590 mg/m3 VME Germany: 50 ppm TWA; 150 mg/m3 TWA Germany: Skin absorber Japan: 200 ppm OEL; 590 mg/m3 OEL Malaysia: 200 ppm TWA; 590 mg/m3 TWA Netherlands: 100 ppm MAC; 300 mg/m3 MAC Russia: 100 mg/m3 TWA Spain: 50 ppm VLA-ED; 150 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 300 mg/m3 VLA-EC Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A NIOSH/MSHA approved or European Standard EN 149 air purifying respirator with an organic vapor cartridge or canister may be permissible under certain circumstances where airborne concentrations are expected.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: -34 deg C ( -29.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 0.861
Molecular Formula: CH5N
Molecular Weight: 31.06
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Prolonged exposure to air and sunlight may form unstable peroxides.
Conditions to Avoid:
Prolonged exposure to air and sunlight may form unstable peroxides., incompatible materials, light, ignition sources.
Incompatibilities with Other Materials:
Sodium hydroxide, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), potassium hydroxide, bromine, metal halides, acids, bases, acid chlorides, acid anhydrides, chloroformates, oxygen, phosphorus halides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Prolonged exposure to air and sunlight may form unstable peroxides.
Conditions to Avoid:
Prolonged exposure to air and sunlight may form unstable peroxides., incompatible materials, light, ignition sources.
Incompatibilities with Other Materials:
Sodium hydroxide, caustics (e.g. ammonia, ammonium hydroxide, calcium hydroxide, potassium hydroxide, sodium hydroxide), oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), potassium hydroxide, bromine, metal halides, acids, bases, acid chlorides, acid anhydrides, chloroformates, oxygen, phosphorus halides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 74-89-5: PF6300000 CAS# 109-99-9: LU5950000 LD50/LC50:
CAS# 74-89-5: Inhalation, mouse: LC50 = 2400 mg/m3/2H; Inhalation, rat: LC50 = 448 ppm/2.5H; Oral, rat: LD50 = 100 mg/kg.
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
Carcinogenicity:
Methylamine - Not listed by ACGIH, IARC, or NTP.
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Other:
See actual entry in RTECS for complete information.
CAS# 74-89-5: PF6300000 CAS# 109-99-9: LU5950000 LD50/LC50:
CAS# 74-89-5: Inhalation, mouse: LC50 = 2400 mg/m3/2H; Inhalation, rat: LC50 = 448 ppm/2.5H; Oral, rat: LD50 = 100 mg/kg.
CAS# 109-99-9: Inhalation, rat: LC50 = 21000 ppm/3H; Oral, rat: LD50 = 1650 mg/kg.
Carcinogenicity:
Methylamine - Not listed by ACGIH, IARC, or NTP.
Tetrahydrofuran - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Blue-green algae, growth inhibition microcystis=225 mg/L (PH=7); Protozoa, cell multiplication inhibition test=858 mg/L.
(See also Dictionary of Substances and Their Effects 1992).
Blue-green algae, growth inhibition microcystis=225 mg/L (PH=7); Protozoa, cell multiplication inhibition test=858 mg/L.
(See also Dictionary of Substances and Their Effects 1992).
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.*
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
IMO
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3 (8)
UN Number: 2924
Packing Group: II
RID/ADR
Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S.
Hazard Class: 3
UN Number: 2924
Packing group: II
USA RQ: CAS# 74-89-5: 100 lb final RQ; 45.4 kg final RQ
USA RQ: CAS# 109-99-9: 1000 lb final RQ; 454 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F+
Risk Phrases:
R 12 Extremely flammable.
R 19 May form explosive peroxides.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 74-89-5: 2
CAS# 109-99-9: 1
Canada
CAS# 74-89-5 is listed on Canadas DSL List.
CAS# 109-99-9 is listed on Canadas DSL List.
CAS# 74-89-5 is listed on Canadas Ingredient Disclosure List.
CAS# 109-99-9 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 74-89-5 is listed on the TSCA inventory.
CAS# 109-99-9 is listed on the TSCA inventory.
