Name:
Methyllithium lithium bromide complex 6% solution in diethyl ether
Synonym:
None
CAS:
0-00-0
Section 1 - Chemical Product
MSDS Name:Methyllithium lithium bromide complex 6% solution in diethyl ether
Synonym:None
Synonym:None
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 0-00-0 | Ethyl ether | Balance | 200-467-2 |
| Hazard Symbols: F+ C Risk Phrases: 12 15 17 34 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Extremely flammable. Contact with water liberates extremely flammable gases. Spontaneously flammable in air. Causes burns.Corrosive.Hygroscopic (absorbs moisture from the air).Air sensitive.Light sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Harmful if absorbed through the skin. Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract.
Aspiration hazard. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. Causes gastrointestinal tract burns. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May be harmful if swallowed.
Inhalation:
Causes chemical burns to the respiratory tract. Vapors may cause dizziness or suffocation. May be absorbed through the lungs.
Inhalation may cause irritation of the nose and throat, vomiting, irregular respiration, dizziness, drowsiness, unconsciousness and possible death due to respiratory paralysis.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. May cause kidney damage. Prolonged exposure to high vapor concentrations may cause eye injury.
Extremely flammable. Contact with water liberates extremely flammable gases. Spontaneously flammable in air. Causes burns.Corrosive.Hygroscopic (absorbs moisture from the air).Air sensitive.Light sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Harmful if absorbed through the skin. Causes skin burns.
Ingestion:
May cause severe and permanent damage to the digestive tract.
Aspiration hazard. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. Causes gastrointestinal tract burns. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal. May be harmful if swallowed.
Inhalation:
Causes chemical burns to the respiratory tract. Vapors may cause dizziness or suffocation. May be absorbed through the lungs.
Inhalation may cause irritation of the nose and throat, vomiting, irregular respiration, dizziness, drowsiness, unconsciousness and possible death due to respiratory paralysis.
Chronic:
Prolonged or repeated skin contact may cause defatting and dermatitis. Prolonged or repeated exposure can cause psychic abnormalities such as anxiety, depression and excitability.
Laboratory experiments have resulted in mutagenic effects. May cause kidney damage. Prolonged exposure to high vapor concentrations may cause eye injury.
Section 4 - FIRST AID MEASURES
Eyes: Get medical aid immediately. Do NOT allow victim to rub eyes or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Possible aspiration hazard. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat symptomatically and supportively.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Possible aspiration hazard. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Persons with kidney disease, chronic respiratory disease, liver disease, or skin disease may be at increased risk from exposure to this substance. Alcoholic beverage consumption may enhance the toxic effects of this substance. Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
May react violently or explosively on contact with water. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished. May ignite on contact with water or moist air. May burn rapidly with flare-burning effect.
Extinguishing Media:
Do NOT get water inside containers. Cool containers with flooding quantities of water until well after fire is out. DO NOT USE WATER, CO2, OR FOAM DIRECTLY ON FIRE ITSELF. For large fires, use dry sand, dry chemical, soda ash or lime or withdraw from area and let fire burn. For small fires, use dry chemical, soda ash, lime or dry sand.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Extremely flammable. Material will readily ignite at room temperature. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire.
May form explosive peroxides. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
May react violently or explosively on contact with water. Will be easily ignited by heat, sparks or flame. May re-ignite after fire is extinguished. May ignite on contact with water or moist air. May burn rapidly with flare-burning effect.
Extinguishing Media:
Do NOT get water inside containers. Cool containers with flooding quantities of water until well after fire is out. DO NOT USE WATER, CO2, OR FOAM DIRECTLY ON FIRE ITSELF. For large fires, use dry sand, dry chemical, soda ash or lime or withdraw from area and let fire burn. For small fires, use dry chemical, soda ash, lime or dry sand.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Place under an inert atmosphere. A vapor suppressing foam may be used to reduce vapors. Cover with dry earth, dry sand, or other non-combustible material followed with plastic sheet to minimize spreading and contact with water.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not ingest or inhale. Store protected from light. Handle under an inert atmosphere. Store protected from air. If peroxide formation is suspected, do not open or move container. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Do not store in direct sunlight. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water.
Flammables-area. Keep refrigerated. (Store below 4C/39F.) Do not expose to air. Store protected from moisture. Store protected from light. Store under an inert atmosphere. Keep away from oxidizing agents.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not ingest or inhale. Store protected from light. Handle under an inert atmosphere. Store protected from air. If peroxide formation is suspected, do not open or move container. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store near combustible materials. Do not store in direct sunlight. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from water.
Flammables-area. Keep refrigerated. (Store below 4C/39F.) Do not expose to air. Store protected from moisture. Store protected from light. Store under an inert atmosphere. Keep away from oxidizing agents.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 0-00-0: CAS# 60-29-7: United Kingdom, WEL - TWA: 100 ppm TWA; 310 mg/m3 TWA United Kingdom, WEL - STEL: 200 ppm STEL; 620 mg/m3 STEL United States OSHA: 400 ppm TWA; 1200 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 308 mg/m3 VLE Belgium - STEL: 200 ppm VLE; 616 mg/m3 VLE France - VME: 400 ppm VME; 1200 mg/m3 VME France - VLE: 500 ppm VLE; 1500 mg/m3 VLE Germany: 400 ppm TWA; 1200 mg/m3 TWA Japan: 400 ppm OEL; 1200 mg/m3 OEL Malaysia: 400 ppm TWA; 1210 mg/m3 TWA Netherlands: 200 ppm STEL; 616 mg/m3 STEL Netherlands: 100 ppm MAC; 308 mg/m3 MAC Russia: 300 mg/m3 TWA Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 616 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 0-00-0: CAS# 60-29-7: United Kingdom, WEL - TWA: 100 ppm TWA; 310 mg/m3 TWA United Kingdom, WEL - STEL: 200 ppm STEL; 620 mg/m3 STEL United States OSHA: 400 ppm TWA; 1200 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 308 mg/m3 VLE Belgium - STEL: 200 ppm VLE; 616 mg/m3 VLE France - VME: 400 ppm VME; 1200 mg/m3 VME France - VLE: 500 ppm VLE; 1500 mg/m3 VLE Germany: 400 ppm TWA; 1200 mg/m3 TWA Japan: 400 ppm OEL; 1200 mg/m3 OEL Malaysia: 400 ppm TWA; 1210 mg/m3 TWA Netherlands: 200 ppm STEL; 616 mg/m3 STEL Netherlands: 100 ppm MAC; 308 mg/m3 MAC Russia: 300 mg/m3 TWA Spain: 100 ppm VLA-ED; 308 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 616 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: colorless to yellow - clear to slightly turbid
Odor: None reported.
pH: Not available.
Vapor Pressure: 570 mbar @ 20 C
Viscosity: 0.245 cP @ 20C
Boiling Point: 34.6 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: -28 deg C ( -18.40 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Slightly soluble.
Specific Gravity/Density: 0.8100g/cm3
Molecular Formula: CH3BrLi2
Molecular Weight: 108.82
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Prolonged exposure to air and sunlight may form unstable peroxides.
Conditions to Avoid:
Incompatible materials, light, ignition sources, dust generation, exposure to air, excess heat, strong acids, strong oxidants, exposure to moist air or water, oxidizers.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, bases, bromine trifluoride, chlorine trifluoride, halogens, nitric acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen peroxide, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate, moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid, peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide, peroxides.
Hazardous Polymerization: Has not been reported.
Prolonged exposure to air and sunlight may form unstable peroxides.
Conditions to Avoid:
Incompatible materials, light, ignition sources, dust generation, exposure to air, excess heat, strong acids, strong oxidants, exposure to moist air or water, oxidizers.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, bases, bromine trifluoride, chlorine trifluoride, halogens, nitric acid, permanganates, silver perchlorate, sodium peroxide, sulfur, sulfuric acid, hydrogen peroxide, ozone, bromine, chromyl chloride, fluorine nitrate, nitrosyl perchlorate, bromine pentafluoride, perchloric acid, chromic anhydride, interhalogens, chlorine, uranyl nitrate, moisture, air, iodine heptafluoride, boron triazide, wood pulp extracts + heat, acetyl peroxide, bromoazide, potassium peroxide, triethyl or trimethyl aluminum + air, lithium aluminum hydride, thiotriazyl perchlorate, nitryl perchlorate, permanganic acid, peroxodisulfuric acid, iodine (VII) oxide, sulfonyl chloride, liquid air.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide, peroxides.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 0-00-0 unlisted.
CAS# 60-29-7: KI5775000 LD50/LC50:
Not available.
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, mouse: LD50 = 1760 mg/kg; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 60-29-7: Dermal, rat: LD50 > 20 Carcinogenicity:
Methyllithium lithium bromide complex - Not listed by ACGIH, IARC, or NTP.
Ethyl ether - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 0-00-0 unlisted.
CAS# 60-29-7: KI5775000 LD50/LC50:
Not available.
CAS# 60-29-7: Draize test, rabbit, eye: 100 mg Moderate; Inhalation, mouse: LC50 = 31000 ppm/30M; Oral, mouse: LD50 = 1760 mg/kg; Oral, rat: LD50 = 1215 mg/kg; Skin, rabbit: LD50 = >20 mL/kg.
CAS# 60-29-7: Dermal, rat: LD50 > 20 Carcinogenicity:
Methyllithium lithium bromide complex - Not listed by ACGIH, IARC, or NTP.
Ethyl ether - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; CAS# 60-29-7: Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; CAS# 60-29-7: Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; CAS# 60-29-7: Microtox testCAS# 60-29-7: If ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Fish: Fathead Minnow: LC50 = 2600 mg/L; 96 Hr; CAS# 60-29-7: Flow-through bioassayFish: Bluegill/Sunfish: LC50 >10000 mg/L; 96 Hr; CAS# 60-29-7: Static bioassayBacteria: Phytobacterium phosphoreum: EC50 = 5625 mg/L; 15 min; CAS# 60-29-7: Microtox testCAS# 60-29-7: If ethyl ether is released to soil, it will be subject to volatilization. It will be expected to exhibit high mobility in soil and, therefore, it may leach to groundwater. If ethyl ether is released to water, it will not be expected to significantly adsorb to sediment or suspended particulate matter, bioconcentrate in aquatic organisms or hydrolyze.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing Group:
IMO
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing Group: I
RID/ADR
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2
UN Number: 2445
Packing group: I
USA RQ: CAS# 60-29-7: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F+ C
Risk Phrases:
R 12 Extremely flammable.
R 15 Contact with water liberates extremely
flammable gases.
R 17 Spontaneously flammable in air.
R 34 Causes burns.
Safety Phrases:
S 6A Keep under nitrogen.
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static
discharges.
S 43B In case of fire, use fire-fighting equipment
on basis of sodium chloride, sodium bicarbonate (never
use water).
WGK (Water Danger/Protection)
CAS# 0-00-0: No information available.
CAS# 60-29-7: 1
Canada
CAS# 60-29-7 is listed on Canadas DSL List.
CAS# 0-00-0 is not listed on Canadas Ingredient Disclosure List.
CAS# 60-29-7 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 0-00-0 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 60-29-7 is listed on the TSCA inventory.
