MSDS Name:n-Butyllithium 2.6M solution in toluene
Synonym:

EMERGENCY OVERVIEW
Highly flammable. Reacts violently with water liberating extremely flammable gases. Spontaneously flammable in air. Causes severe burns.
Harmful by inhalation. Possible risk of harm to the unborn child.
Vapours may cause drowsiness and dizziness.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Harmful if inhaled. Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Material can spontaneously ignite (pyrophoric) when exposed to air at normal or slightly elevated temperatures. Water Reactive. Material will react with water and may release a flammable and/or toxic gas.
Extinguishing Media:
DO NOT USE WATER! Do NOT use water, carbon dioxide, or foam. Smother with dry sand, dry clay, dry ground limestone (CaCO3), or use approved Class D extinguishers.

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Do not expose spill to water.

Handling:
Do not allow water to get into the container because of violent reaction. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Do not allow contact with water. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place.
Store in a tightly closed container. Flammables-area. Corrosives area. Water free area. Store under nitrogen.

Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 108-88-3: United Kingdom, WEL - TWA: 50 ppm TWA; 191 mg/m3 TWA United Kingdom, WEL - STEL: 150 ppm STEL; 574 mg/m3 STEL United States OSHA: 200 ppm TWA; 300 ppm Ceiling Belgium - TWA: 50 ppm VLE; 191 mg/m3 VLE France - VME: 100 ppm VME; 375 mg/m3 VME France - VLE: 150 ppm VLE; 550 mg/m3 VLE Germany: 50 ppm TWA; 190 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 188 mg/m3 OEL Malaysia: 50 ppm TWA; 188 mg/m3 TWA Netherlands: 40 ppm MAC; 150 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 191 mg/m3 VLA-ED CAS# 109-72-8: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Physical State: Liquid
Color: light yellow
Odor: solvent odor
pH: ca 7
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: vigorous reaction
Specific Gravity/Density: 0.860
Molecular Formula: C4H9Li
Molecular Weight: 64.06

Chemical Stability:
Powder or liquid is pyrophoric. Air sensitive. Reacts violently with water. Moisture sensitive. Light sensitive.
Conditions to Avoid:
Incompatible materials, ignition sources, exposure to air, exposure to moist air or water, direct sunlight..
Incompatibilities with Other Materials:
Contact with water liberates highly flammable gases., oxidizing agents, acids, alcohols, carbon dioxide, oxygen, hydrogen, organic halides.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, butane, lithium oxide.
Hazardous Polymerization: Has not been reported

RTECS#:
CAS# 108-88-3: XS5250000 CAS# 109-72-8 unlisted.
LD50/LC50:
CAS# 108-88-3: Draize test, rabbit, eye: 870 ug Mild; Draize test, rabbit, eye: 2 mg/24H Severe; Draize test, rabbit, skin: 435 mg Mild; Draize test, rabbit, skin: 500 mg Moderate; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 400 ppm/24H; Inhalation, mouse: LC50 = 30000 mg/m3/2H; Inhalation, mouse: LC50 = 19900 mg/m3/7H; Inhalation, mouse: LC50 = 10000 mg/m3; Inhalation, rat: LC50 = 49 gm/m3/4H; Oral, rat: LD50 = 636 mg/kg; Skin, rabbit: LD50 = 14100 uL/kg.
CAS# 109-72-8.
Carcinogenicity:
Toluene - Not listed by ACGIH, IARC, or NTP.
Butyl lithium - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Dispose of in a manner consistent with federal, state, and local regulations.

IATA
Shipping Name: LITHIUM ALKYLS (forbidden to ship via cargo or pas
senger aircraft).
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing Group: I
IMO
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing Group: I
RID/ADR
Shipping Name: LITHIUM ALKYLS
Hazard Class: 4.2 (4.3)
UN Number: 2445
Packing group: I
USA RQ: CAS# 108-88-3: 1000 lb final RQ; 454 kg final RQ

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: F C
Risk Phrases:
R 11 Highly flammable.
R 14/15 Reacts violently with water liberating
extremely flammable gases.
R 17 Spontaneously flammable in air.
R 20 Harmful by inhalation.
R 35 Causes severe burns.
R 63 Possible risk of harm to the unborn child.
R 67 Vapours may cause drowsiness and dizziness.
Safety Phrases:
S 6A Keep under nitrogen.
S 16 Keep away from sources of ignition - No
smoking.
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 33 Take precautionary measures against static
discharges.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 43B In case of fire, use fire-fighting equipment
on basis of sodium chloride, sodium bicarbonate (never
use water).
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
CAS# 109-72-8: 2
Canada
CAS# 108-88-3 is listed on Canadas DSL List.
CAS# 109-72-8 is listed on Canadas DSL List.
CAS# 108-88-3 is listed on Canadas Ingredient Disclosure List.
CAS# 109-72-8 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 108-88-3 is listed on the TSCA inventory.
CAS# 109-72-8 is listed on the TSCA inventory.