Name:
N-Methylpyrrolidinone extra dry water
Synonym:
2-Pyrrolidinone, 1-methyl-; N-Methylpyrrolidinone; N-Methyl-2-pyrrolidinone; 1-Methyl-5-pyrrolidinone; N-Methylpyrrolidone; N-Methyl-alpha-pyrrolidone; N-Methyl-2-pyrrolidone; 1-Methyl-2-pyrrolidone; M-Pyrol; NMP
CAS:
872-50-4
Section 1 - Chemical Product
MSDS Name:N-Methylpyrrolidinone extra dry water
Synonym:2-Pyrrolidinone, 1-methyl-; N-Methylpyrrolidinone; N-Methyl-2-pyrrolidinone; 1-Methyl-5-pyrrolidinone; N-Methylpyrrolidone; N-Methyl-alpha-pyrrolidone; N-Methyl-2-pyrrolidone; 1-Methyl-2-pyrrolidone; M-Pyrol; NMP
Synonym:2-Pyrrolidinone, 1-methyl-; N-Methylpyrrolidinone; N-Methyl-2-pyrrolidinone; 1-Methyl-5-pyrrolidinone; N-Methylpyrrolidone; N-Methyl-alpha-pyrrolidone; N-Methyl-2-pyrrolidone; 1-Methyl-2-pyrrolidone; M-Pyrol; NMP
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 872-50-4 | N-Methylpyrrolidinone | >99.5 | 212-828-1 |
| Hazard Symbols: XI Risk Phrases: 36/38 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes and skin.Hygroscopic.Light sensitive.
Potential Health Effects
Eye:
Causes moderate eye irritation. May cause temporary corneal clouding.
Skin:
Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth. Inhalation of vapors in confined spaces or when hot may cause drowsiness, dizziness, headache, nausea, or lung irritation.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects.
Irritating to eyes and skin.Hygroscopic.Light sensitive.
Potential Health Effects
Eye:
Causes moderate eye irritation. May cause temporary corneal clouding.
Skin:
Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation:
Causes respiratory tract irritation. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth. Inhalation of vapors in confined spaces or when hot may cause drowsiness, dizziness, headache, nausea, or lung irritation.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Skin:
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Containers may explode when heated. Toxic oxides of nitrogen may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use extinguishing media most appropriate for the surrounding fire. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Containers may explode when heated. Toxic oxides of nitrogen may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use extinguishing media most appropriate for the surrounding fire. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Store protected from light. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Store protected from light. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Personal Protective Equipment Eyes: Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Personal Protective Equipment Eyes: Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR ??1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirators use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Appearance: clear, colorless
Odor: mild odor, amine-like
pH: 7.7-8.0 (100g/l aq.
Vapor Pressure: 0.3 mm Hg @ 20C
Viscosity: 1.65 cp @ 25 C
Boiling Point: 202 deg C @ 760 mmHg
Freezing/Melting Point: -24 deg C
Autoignition Temperature: 346 deg C ( 654.80 deg F)
Flash Point: 91 deg C ( 195.80 deg F)
Explosion Limits, lower: 1.3%
Explosion Limits, upper: 9.5%
Decomposition Temperature: Not available.
Solubility in water: Miscible.
Specific Gravity/Density: 1.028
Molecular Formula: C5H9NO
Molecular Weight: 99.13
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Light sensitive.
Conditions to Avoid:
Light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Chlorinating agents, sulfur, carbon disulfide, strong acids, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Stable at room temperature in closed containers under normal storage and handling conditions. Light sensitive.
Conditions to Avoid:
Light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Chlorinating agents, sulfur, carbon disulfide, strong acids, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 872-50-4: UY5790000 LD50/LC50:
CAS# 872-50-4: Draize test, rabbit, eye: 100 mg Moderate; Oral, mouse: LD50 = 5130 mg/kg; Oral, rat: LD50 = 3914 mg/kg; Skin, rabbit: LD50 = 8 gm/kg.
Carcinogenicity:
N-Methylpyrrolidinone - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
CAS# 872-50-4: UY5790000 LD50/LC50:
CAS# 872-50-4: Draize test, rabbit, eye: 100 mg Moderate; Oral, mouse: LD50 = 5130 mg/kg; Oral, rat: LD50 = 3914 mg/kg; Skin, rabbit: LD50 = 8 gm/kg.
Carcinogenicity:
N-Methylpyrrolidinone - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Rainbow trout: LC50 = 5104 mg/L; 96 Hr; UnspecifiedFish: Fathead Minnow: LC50 = 4518.27 mg/L; 96 Hr; UnspecifiedFish: Bluegill/Sunfish: LC50 = 5656 mg/L; 96 Hr; UnspecifiedWater flea Daphnia: LC50 = 3135 mg/L; 96 Hr; Unspecified1-Methyl-2-pyrrolidinone is expected to show very high soil mobility and slowly volatilize from dry soil to the atmosphere, but it is not expected to significantly volatilize from moist soil.
This product will biodegrade in water under aerobic conditions after a short lag period. Estimated BCF value = 0.16. This value suggest that this substance is not expected to significantly bioconcentrate
Fish: Rainbow trout: LC50 = 5104 mg/L; 96 Hr; UnspecifiedFish: Fathead Minnow: LC50 = 4518.27 mg/L; 96 Hr; UnspecifiedFish: Bluegill/Sunfish: LC50 = 5656 mg/L; 96 Hr; UnspecifiedWater flea Daphnia: LC50 = 3135 mg/L; 96 Hr; Unspecified1-Methyl-2-pyrrolidinone is expected to show very high soil mobility and slowly volatilize from dry soil to the atmosphere, but it is not expected to significantly volatilize from moist soil.
This product will biodegrade in water under aerobic conditions after a short lag period. Estimated BCF value = 0.16. This value suggest that this substance is not expected to significantly bioconcentrate
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/38 Irritating to eyes and skin.
Safety Phrases:
S 41 In case of fire and/or explosion do not breathe
fumes.
WGK (Water Danger/Protection)
CAS# 872-50-4: 1
United Kingdom Occupational Exposure Limits
CAS# 872-50-4: OES-United Kingdom, TWA 25 ppm TWA; 103 mg/m3 TWA
CAS# 872-50-4: OES-United Kingdom, STEL 75 ppm STEL; 309 mg/m3 STEL
Canada
CAS# 872-50-4 is listed on Canadas DSL List.
CAS# 872-50-4 is not listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 872-50-4: OEL-DENMARK:TWA 100 ppm (400 mg/m3)
OEL-GERMANY:TWA 100 ppm (400 mg/m3)
OEL-THE NETHERLANDS:TWA 100 ppm (400 mg/m3)
OEL-RUSSIA:STEL 100 mg/m3
OEL-SWITZERLAND:TWA 200 ppm (400 mg/m3)
OEL-UNITED KINGDOM:TWA 100 ppm (400 mg/m3)
US FEDERAL
TSCA
CAS# 872-50-4 is listed on the TSCA inventory.
