Name:
N-Nitrosodimethylamine 99+%
Synonym:
Dimethylnitrosamine; Dimethylnitrosoamine; DMN; DMNA; N,N-Dimethylnitrosamine; N-Methyl-N-nitrosomethanamine; N-Nitroso-N,N-dimethylamine; N-Nitrosodimethylamine; NDMA; Nitrosodimethylamine
CAS:
62-75-9
Section 1 - Chemical Product
MSDS Name:N-Nitrosodimethylamine 99+%
Synonym:Dimethylnitrosamine; Dimethylnitrosoamine; DMN; DMNA; N,N-Dimethylnitrosamine; N-Methyl-N-nitrosomethanamine; N-Nitroso-N,N-dimethylamine; N-Nitrosodimethylamine; NDMA; Nitrosodimethylamine
Synonym:Dimethylnitrosamine; Dimethylnitrosoamine; DMN; DMNA; N,N-Dimethylnitrosamine; N-Methyl-N-nitrosomethanamine; N-Nitroso-N,N-dimethylamine; N-Nitrosodimethylamine; NDMA; Nitrosodimethylamine
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 62-75-9 | N-Nitrosodimethylamine | >99 | 200-549-8 |
| Hazard Symbols: T+ N Risk Phrases: 25 26 45 48/25 51/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic if swallowed. Very toxic by inhalation. May cause cancer.
Toxic : danger of serious damage to health by prolonged exposure if swallowed. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Light sensitive.Dangerous for the environment.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
May cause irritation and dermatitis. May cause cyanosis of the extremities.
Ingestion:
May be fatal if swallowed. May cause headache, fever, nausea, abdominal pain, muscle pain and bloody urine.
Inhalation:
Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
Chronic:
Prolonged or repeated exposure may cause changes in the esophagus, ulceration, and bleeding from the small or large intestine.
Toxic if swallowed. Very toxic by inhalation. May cause cancer.
Toxic : danger of serious damage to health by prolonged exposure if swallowed. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Light sensitive.Dangerous for the environment.Cancer suspect agent.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
May cause irritation and dermatitis. May cause cyanosis of the extremities.
Ingestion:
May be fatal if swallowed. May cause headache, fever, nausea, abdominal pain, muscle pain and bloody urine.
Inhalation:
Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.
Chronic:
Prolonged or repeated exposure may cause changes in the esophagus, ulceration, and bleeding from the small or large intestine.
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Induce vomiting only when instructed to do so by a physician.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician:
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Induce vomiting only when instructed to do so by a physician.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Use water spray to keep fire-exposed containers cool. Combustible liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. Use water spray to keep fire-exposed containers cool. Combustible liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Wash area with soap and water. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Spills/Leaks:
Wash area with soap and water. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Store protected from light. Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Do not ingest or inhale. Store protected from light. Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. See 29CFR 1910.1003 for specific regulatory requirements applying to areas containing a listed carcinogen, signs, training, reports, and medical surveillance programs.
Exposure Limits CAS# 62-75-9: United States OSHA: ; (Cancer suspect agent - see 29 CFR 1910.101 Germany: 0.0025 mg/m3 TWA (vulcanization and following working procedures including stora Netherlands: 0.0007 ppm MAC; 0.002 mg/m3 MAC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. See 29CFR 1910.1003 for specific regulatory requirements applying to areas containing a listed carcinogen, signs, training, reports, and medical surveillance programs.
Exposure Limits CAS# 62-75-9: United States OSHA: ; (Cancer suspect agent - see 29 CFR 1910.101 Germany: 0.0025 mg/m3 TWA (vulcanization and following working procedures including stora Netherlands: 0.0007 ppm MAC; 0.002 mg/m3 MAC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Clear liquid
Color: Clear
Odor: characteristic odor
pH: Not available.
Vapor Pressure: 3 mm Hg @ 25 deg C
Viscosity: Low
Boiling Point: 153 deg C @ 774 mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: 61 deg C ( 141.80 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: soluble
Specific Gravity/Density: 1.0060g/cm3
Molecular Formula: C2H6N2O
Molecular Weight: 74.08
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. May decompose on exposure to ultraviolet light.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, ultra violet light.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures. May decompose on exposure to ultraviolet light.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, ultra violet light.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 62-75-9: IQ0525000 LD50/LC50:
CAS# 62-75-9: Inhalation, mouse: LC50 = 57 ppm/4H; Inhalation, rat: LC50 = 78 ppm/4H; Oral, rat: LD50 = 37 mg/kg.
Oral, woman: LDLo = 20 mg/kg/2.5Y. (ulceration and bleeting of small intestine, nausea, Carcinogenicity:
N-Nitrosodimethylamine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 10/1/87 NTP: Suspect carcinogen IARC: Group 2A carcinogen Other:
See actual entry in RTECS for complete information.
CAS# 62-75-9: IQ0525000 LD50/LC50:
CAS# 62-75-9: Inhalation, mouse: LC50 = 57 ppm/4H; Inhalation, rat: LC50 = 78 ppm/4H; Oral, rat: LD50 = 37 mg/kg.
Oral, woman: LDLo = 20 mg/kg/2.5Y. (ulceration and bleeting of small intestine, nausea, Carcinogenicity:
N-Nitrosodimethylamine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 10/1/87 NTP: Suspect carcinogen IARC: Group 2A carcinogen Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
LD50: Rainbow trout, ip: 177 mg/kg/10d.
LD50: Crayfish, male (adult): 2250 mg/kg.
LD50: Rainbow trout, ip: 177 mg/kg/10d.
LD50: Crayfish, male (adult): 2250 mg/kg.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2810
Packing Group: II
IMO
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing Group: II
RID/ADR
Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2810
Packing group: II
USA RQ: CAS# 62-75-9: 10 lb final RQ; 4.54 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 45 May cause cancer.
R 25 Toxic if swallowed.
R 26 Very toxic by inhalation.
R 48/25 Toxic : danger of serious damage to health
by prolonged exposure if swallowed.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 62-75-9: No information available.
Canada
CAS# 62-75-9 is listed on Canadas NDSL List.
CAS# 62-75-9 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 62-75-9 is listed on the TSCA inventory.
