Name:
Nicotine sulfate 40% aqueous solution
Synonym:
L-1-Methyl-2-(3-pyridyl)pyrrolidine sulfate; (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine sulfate
CAS:
65-30-5
Section 1 - Chemical Product
MSDS Name:Nicotine sulfate 40% aqueous solution
Synonym:L-1-Methyl-2-(3-pyridyl)pyrrolidine sulfate; (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine sulfate
Synonym:L-1-Methyl-2-(3-pyridyl)pyrrolidine sulfate; (S)-3-(1-Methyl-2-pyrrolidinyl)pyridine sulfate
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 65-30-5 | Nicotine sulfate | 40 | 200-606-7 |
| Hazard Symbols: T+ N Risk Phrases: 26/27/28 51/53 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be fatal if absorbed through the skin.
Ingestion:
May be fatal if swallowed. May cause irritation of the digestive tract. May cause central nervous system stimulation.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation. May cause lung damage.
Chronic:
Adverse reproductive effects have been reported in animals. May cause lung damage.
Very toxic by inhalation, in contact with skin and if swallowed.
Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be fatal if absorbed through the skin.
Ingestion:
May be fatal if swallowed. May cause irritation of the digestive tract. May cause central nervous system stimulation.
Inhalation:
Harmful if inhaled. May cause respiratory tract irritation. May cause lung damage.
Chronic:
Adverse reproductive effects have been reported in animals. May cause lung damage.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Remove all contaminated clothing immediately.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes. Remove all contaminated clothing immediately.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Use extinguishing media appropriate to the surrounding fire. Substance is noncombustible.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Do NOT use straight streams of water. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use water spray, fog or regular foam. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Use extinguishing media appropriate to the surrounding fire. Substance is noncombustible.
Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated.
Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Do NOT use straight streams of water. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use water spray, fog or regular foam. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 65-30-5: Russia: 0.1 mg/m3 TWA CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 65-30-5: Russia: 0.1 mg/m3 TWA CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHAs 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Viscous liquid
Color: brown
Odor: sulfurous odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density: 1.15 @ 20C
Molecular Formula: C10H14N2.0.5H2SO4
Molecular Weight: 211.27
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Extreme temperatures.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported
Stable under normal temperatures and pressures.
Conditions to Avoid:
Extreme temperatures.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Has not been reported
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 65-30-5: QS9625000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 65-30-5: Inhalation, rat: LC50 = 22 mg/m3; Oral, mouse: LD50 = 8550 ug/kg; Oral, rat: LD50 = 50 mg/kg; Skin, rabbit: LD50 = 50 mg/kg; Skin, rat: LD50 = 285 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Nicotine sulfate - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
CAS# 65-30-5: QS9625000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 65-30-5: Inhalation, rat: LC50 = 22 mg/m3; Oral, mouse: LD50 = 8550 ug/kg; Oral, rat: LD50 = 50 mg/kg; Skin, rabbit: LD50 = 50 mg/kg; Skin, rat: LD50 = 285 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Nicotine sulfate - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: NICOTINE SULPHATE SOLUTION
Hazard Class: 6.1
UN Number: 1658
Packing Group: II
IMO
Shipping Name: NICOTINE SULPHATE SOLUTION
Hazard Class: 6.1
UN Number: 1658
Packing Group: II
RID/ADR
Shipping Name: NICOTINE SULPHATE SOLUTION
Hazard Class: 6.1
UN Number: 1658
Packing group: II
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 13 Keep away from food, drink and animal feeding
stuffs.
S 28A After contact with skin, wash immediately with
plenty of water.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 65-30-5: No information available.
CAS# 7732-18-5: No information available.
Canada
CAS# 65-30-5 is listed on Canadas DSL List.
CAS# 7732-18-5 is listed on Canadas DSL List.
CAS# 65-30-5 is not listed on Canadas Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 65-30-5 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.
