Name:
o-Phenylenediamine 98%
Synonym:
1,2-Diaminobenzene; 2-Aminoaniline
CAS:
95-54-5
Section 1 - Chemical Product
MSDS Name:o-Phenylenediamine 98%
Synonym:1,2-Diaminobenzene; 2-Aminoaniline
Synonym:1,2-Diaminobenzene; 2-Aminoaniline
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 95-54-5 | 1,2-Phenylenediamine | 98 | 202-430-6 |
| Hazard Symbols: T N Risk Phrases: 20/21 25 36 40 43 50/53 68 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful by inhalation and in contact with skin. Toxic if swallowed.
Irritating to eyes. Limited evidence of a carcinogenic effect. May cause sensitization by skin contact. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Possible risk of irreversible effects.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
May cause irritation of the digestive tract. May cause liver and kidney damage. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed. Overexposure may cause methemoglobinemia.
Inhalation:
Dust is irritating to the respiratory tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobin.
Chronic:
Chronic ingestion may cause liver damage. Prolonged or repeated skin contact may cause dermatitis. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death.
Harmful by inhalation and in contact with skin. Toxic if swallowed.
Irritating to eyes. Limited evidence of a carcinogenic effect. May cause sensitization by skin contact. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Possible risk of irreversible effects.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
May cause irritation of the digestive tract. May cause liver and kidney damage. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed. Overexposure may cause methemoglobinemia.
Inhalation:
Dust is irritating to the respiratory tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, shortness of breath, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobin.
Chronic:
Chronic ingestion may cause liver damage. Prolonged or repeated skin contact may cause dermatitis. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis (bluish skin due to deficient oxygenation of blood), rapid heart rate, unconsciousness and possible death.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood.
Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene Blue depending on the methemoglobin concentration in the blood.
Antidote: Methylene blue, alone or in combination with oxygen is indicated as a treatment in nitrite induced methemoglobinemia.
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode when heated. Combustible material; may burn but does not ignite readily.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, or water spray.
For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode when heated. Combustible material; may burn but does not ignite readily.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, or water spray.
For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels below recommended exposure limits. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHAs eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Crystals
Color: brown yellow, red brown or brown
Odor: acetic odor
pH: Not available.
Vapor Pressure: 0.01 mm Hg @ 25C
Viscosity: Not available.
Boiling Point: 257 deg C
Freezing/Melting Point: 100-103 deg C
Autoignition Temperature: Not applicable.
Flash Point: 110 deg C ( 230.00 deg F)
Explosion Limits, lower: 1.5%
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Slightly soluble.
Specific Gravity/Density: Not available.
Molecular Formula: C6H8N2
Molecular Weight: 108.14
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 95-54-5: SS7875000 LD50/LC50:
CAS# 95-54-5: Inhalation, mouse: LC50 = >91 mg/m3/4H; Inhalation, rat: LC50 = 1873 mg/m3; Oral, mouse: LD50 = 366 mg/kg; Oral, rat: LD50 = 510 mg/kg; Skin, rat: LD50 = >5 gm/kg.
Carcinogenicity:
1,2-Phenylenediamine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 5/15/98 Other:
See actual entry in RTECS for complete information.
CAS# 95-54-5: SS7875000 LD50/LC50:
CAS# 95-54-5: Inhalation, mouse: LC50 = >91 mg/m3/4H; Inhalation, rat: LC50 = 1873 mg/m3; Oral, mouse: LD50 = 366 mg/kg; Oral, rat: LD50 = 510 mg/kg; Skin, rat: LD50 = >5 gm/kg.
Carcinogenicity:
1,2-Phenylenediamine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 5/15/98 Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Ecotoxicity:
Fish: Brown trout: 265mg/L; 96HFish: Fathead Minnow: 44mg/L; 96HFish: Bluegill/Sunfish: 280mg/L; 96HThe product is chemically identically to the natural amino acid L-Serine and can therefore be degraded microbiologically.
Fish: Brown trout: 265mg/L; 96HFish: Fathead Minnow: 44mg/L; 96HFish: Bluegill/Sunfish: 280mg/L; 96HThe product is chemically identically to the natural amino acid L-Serine and can therefore be degraded microbiologically.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: PHENYLENEDIAMINES
Hazard Class: 6.1
UN Number: 1673
Packing Group: III
IMO
Shipping Name: PHENYLENEDIAMINES (O-, M-, P-)
Hazard Class: 6.1
UN Number: 1673
Packing Group: III
RID/ADR
Shipping Name: PHENYLENEDIAMINES
Hazard Class: 6.1
UN Number: 1673
Packing group: III
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 20/21 Harmful by inhalation and in contact with
skin.
R 25 Toxic if swallowed.
R 36 Irritating to eyes.
R 40 Limited evidence of a carcinogenic effect.
R 43 May cause sensitization by skin contact.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
R 68 Possible risk of irreversible effects.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 95-54-5: 3
United Kingdom Occupational Exposure Limits
United Kingdom Maximum Exposure Limits
Canada
CAS# 95-54-5 is listed on Canadas DSL List.
CAS# 95-54-5 is listed on Canadas Ingredient Disclosure List.
Exposure Limits
CAS# 95-54-5: Not available.
US FEDERAL
TSCA
CAS# 95-54-5 is listed on the TSCA inventory.
