Name:
o-Toluidine 99%
Synonym:
2-Aminotoluene; 2-Methylaniline; 2-Methylbenzamin
CAS:
95-53-4
Section 1 - Chemical Product
MSDS Name:o-Toluidine 99%
Synonym:2-Aminotoluene; 2-Methylaniline; 2-Methylbenzamin
Synonym:2-Aminotoluene; 2-Methylaniline; 2-Methylbenzamin
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | emsds | EINECS# |
| 95-53-4 | o-Toluidine | 99% | 202-429-0 |
| Hazard Symbols: T N Risk Phrases: 23/25 36 45 50 |
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation and if swallowed. Irritating to eyes. May cause cancer. Very toxic to aquatic organisms.Light sensitive.Air sensitive.
Potential Health Effects
Eye:
Causes severe eye irritation. Causes redness and pain.
Skin:
Causes mild skin irritation. May be absorbed through the skin.
Causes symptoms similar to those of inhalation.
Ingestion:
Poison by ingestion. May cause effects similar to those for inhalation exposure. May cause headache.
Inhalation:
Causes cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Toxic if inhaled. May cause drowsiness, unconsciousness, and central nervous system depression.
Chronic:
May cause kidney injury. Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Toxic by inhalation and if swallowed. Irritating to eyes. May cause cancer. Very toxic to aquatic organisms.Light sensitive.Air sensitive.
Potential Health Effects
Eye:
Causes severe eye irritation. Causes redness and pain.
Skin:
Causes mild skin irritation. May be absorbed through the skin.
Causes symptoms similar to those of inhalation.
Ingestion:
Poison by ingestion. May cause effects similar to those for inhalation exposure. May cause headache.
Inhalation:
Causes cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood). Toxic if inhaled. May cause drowsiness, unconsciousness, and central nervous system depression.
Chronic:
May cause kidney injury. Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood).
Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid immediately. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid immediately. Wash mouth out with water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Combustible liquid.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Combustible liquid.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Provide ventilation.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Provide ventilation.
Section 7 - HANDLING and STORAGE
Handling:
Use only in a well-ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Keep under a nitrogen blanket. Poison room locked.
Use only in a well-ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Keep under a nitrogen blanket. Poison room locked.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 95-53-4: United Kingdom, WEL - TWA: 0.2 ppm TWA; 0.89 mg/m3 TWA United Kingdom, WEL - STEL: 0.6 ppm STEL; 2.67 mg/m3 STEL United States OSHA: 5 ppm TWA; 22 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 8.9 mg/m3 VLE France - VME: 2 ppm VME; 9 mg/m3 VME Germany: 0.5 mg/m3 TWA Germany: Skin absorber Japan: 1 ppm OEL; 4.4 mg/m3 OEL Malaysia: 2 ppm TWA; 8.8 mg/m3 TWA Russia: 1 mg/m3 TWA Russia: 0.5 mg/m3 STEL Spain: 0.2 ppm VLA-ED; 0.89 mg/m3 VLA-ED Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 95-53-4: United Kingdom, WEL - TWA: 0.2 ppm TWA; 0.89 mg/m3 TWA United Kingdom, WEL - STEL: 0.6 ppm STEL; 2.67 mg/m3 STEL United States OSHA: 5 ppm TWA; 22 mg/m3 TWA Belgium - TWA: 2 ppm VLE; 8.9 mg/m3 VLE France - VME: 2 ppm VME; 9 mg/m3 VME Germany: 0.5 mg/m3 TWA Germany: Skin absorber Japan: 1 ppm OEL; 4.4 mg/m3 OEL Malaysia: 2 ppm TWA; 8.8 mg/m3 TWA Russia: 1 mg/m3 TWA Russia: 0.5 mg/m3 STEL Spain: 0.2 ppm VLA-ED; 0.89 mg/m3 VLA-ED Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Clear liquid
Color: yellow - light brown
Odor: amine-like
pH: Not available.
Vapor Pressure: 0.2 mbar @ 20 deg C
Viscosity: mPas 20 deg C
Boiling Point: 199 - 200 deg C @ 760.00mm Hg
Freezing/Melting Point: -23 deg C
Autoignition Temperature: 480 deg C ( 896.00 deg F)
Flash Point: 85 deg C ( 185.00 deg F)
Explosion Limits, lower: 1.50 vol %
Explosion Limits, upper: 7.50 vol %
Decomposition Temperature: >200 deg C
Solubility in water: 1.5 G/100ML (25C)
Specific Gravity/Density: 1.0040g/cm3
Molecular Formula: CH3C6H4NH2
Molecular Weight: 107.15
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 95-53-4: XU2975000 LD50/LC50:
CAS# 95-53-4: Draize test, rabbit, eye: 750 ug/24H Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = 862 ppm/4H; Oral, mouse: LD50 = 520 mg/kg; Oral, rabbit: LD50 = 840 mg/kg; Oral, rat: LD50 = 670 mg/kg; Skin, rabbit: LD50 = 3250 uL/kg.
Carcinogenicity:
o-Toluidine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2A carcinogen Other:
See actual entry in RTECS for complete information.
CAS# 95-53-4: XU2975000 LD50/LC50:
CAS# 95-53-4: Draize test, rabbit, eye: 750 ug/24H Severe; Draize test, rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = 862 ppm/4H; Oral, mouse: LD50 = 520 mg/kg; Oral, rabbit: LD50 = 840 mg/kg; Oral, rat: LD50 = 670 mg/kg; Skin, rabbit: LD50 = 3250 uL/kg.
Carcinogenicity:
o-Toluidine - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 1/1/88 NTP: Suspect carcinogen IARC: Group 2A carcinogen Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Other No information available.
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Shipping Name: TOLUIDINES, LIQUID
Hazard Class: 6.1
UN Number: 1708
Packing Group: II
IMO
Shipping Name: TOLUIDINES, LIQUID
Hazard Class: 6.1
UN Number: 1708
Packing Group: II
RID/ADR
Shipping Name: TOLUIDINES, LIQUID
Hazard Class: 6.1
UN Number: 1708
Packing group: II
USA RQ: CAS# 95-53-4: 100 lb final RQ; 45.4 kg final RQ
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 45 May cause cancer.
R 23/25 Toxic by inhalation and if swallowed.
R 36 Irritating to eyes.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 95-53-4: 3
Canada
CAS# 95-53-4 is listed on Canadas DSL List.
CAS# 95-53-4 is listed on Canadas Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 95-53-4 is listed on the TSCA inventory.
